查询词典 manner of expression

Incubation of the yeast cell with various concentrations of the estrogenic compounds led to expression of the reporter gene product GFP in a dose dependent manner.

该酵母细胞经不同浓度的雌激素类化合物作用后，发现GFP的表达量与此类受试物具有明显的剂量效应关系。

RESULTS: The kwoninone has an could significantly inhibit fibroblastic proliferation, growth and expression of TGF-β1 in concentration-dependent manner.

结果：苦参素能明显抑制成纤维细胞增殖及TGF-β1的表达，并呈剂量依靠性。

During embryonic development, Hox proteins can interact with different cofactors and regulate downstream gene expression in a tissue specific manner.

在胚胎发育过程中，Hox蛋白实现时间特异性及组织特异性基因表达调控功能的机制之一是与不同的辅助因子相结合。

Results: When the concentrations of artemisinin were 1×10^(-4), 1×10^(-5) and 1×10^(-6)mol/L, the growth of cells was inhibited remarkably in a dose-dependent manner. Fluorescence staining showed obvious apoptosis, such as karyopyknosis and agglutination. RT-PCR assay shows the expression of Caspase-3. Artemisinin could lead to the decrease of mitochondrial cytochrome c concentration, which in turn lead to the increase of cytoplasmic cytochrome c concentration.

结果：青蒿素的浓度为1×10^(-4)，1×10^(-5)，1×10^(-6)mol/L时，细胞生长受到显著抑制，并呈剂量依赖性；Hoechst33342/PI双荧光染色可观察到明显的核浓缩、凝集等细胞凋亡表现；RT-PCR检测到Caspase-3的表达；Western-blot检测1×10^(-5)mol/L药物处理细胞后线粒体细胞色素C表达水平下调，细胞浆出现明显细胞色素C蛋白条带。

Results HE staining showed that sulindac could inhibit the growth of tumor cells, with the morphological presentations as apoptosis and necrosis including pyknosis, karyorrhexis and chromatin crescent formation, etc. By electron microscopy, cells also had apoptotic characteristics including chromatin crescent formation and apoptotic body. Immunohistochemistry and Western-blot assay results showed that 48 hours after sulindac administration, the expression of NF-κB, bcl-2 and bax gradually decreased, while the level of bax protein gradually increased, in a dose dependence manner.

结果 苏木精－伊红染色检测结果显示舒林酸抑制肿瘤细胞生长，肿瘤细胞出现核固缩、核碎裂、染色质边集等凋亡及坏死的形态学表现；电镜下可看到染色质边集、凋亡小体；免疫组化、Western-blot结果显示舒林酸作用48 h后人胃癌SGC-7901细胞NF-κB、bcl-2表达逐渐下降，bax表达逐渐上升，具有剂量依赖性。

Results showed that nitroprusside inhibited Expression of VCAM-1 protein and mRNA in a dose-and time-dependent manner.

结果表示：一氧化氮抑制IL-1α诱发的内皮细胞粘附分子VCAM-1的基因表达水平其作用呈浓度及时间依赖性。

In vitro, K-ras mutation ASODN could apparently inhibit the growth of Patu 8988 cells （ in a certain degree of dose-dependent and time-dependent manner）,induce apoptosis and decrease the expression of K-ms protein and K-ras mRNA in contrast with SODN, RODN and control groups.

针对K-ras基因第12密码子点突变的反义寡核苷酸可明显抑制人胰腺癌Patu 8988细胞生长，促进细胞凋亡，其机制可能是通过下调K-ras蛋白和K—ras mRNA表达而起作用。

RESULTS: HE stained cells were fusiform-shaped with pseudopodia, round or oval nucleus. The cytoplasm was blue after stained with the toluidine blue. The immunohistochemical test revealed that there existed positive expression of type Ⅰ collagen in the cells. In the presence of 10% calf serum, IGF-Ⅰ significantly improved cell proliferative activity in a dose-dependent manner within effective dose range.

结果：苏木精－伊红染色细胞多为梭形，有伪足伸出，细胞核为圆形或椭圆形；甲苯胺蓝染色，胞浆为深蓝色；免疫细胞学方法检测表明纤维环细胞有Ⅰ型胶原表达；在体积分数为0.1的血清条件下，胰岛素样生长因子Ⅰ能提高细胞的增殖活性，并且在有效浓度范围内呈剂量效应关系。

Results IL-6 significantly increased the expression of SAA in 3T3-L1 adipocytes in a dose- and time-dependent manner.

结果 TNF-a能显著促进3T3-L1脂肪细胞SAA的表达，并呈剂量和时间依赖方式。

Kinase activity assay method was used to estimate the activity of caspase-3 in the cells. RESULTS: Compared with control group and SOND group, in ASODN groups, the expression of survivin mRNA and protein were obviously weaken, apoptosis rate and caspase-3 activity apparently increased, cells growth was inhibited. In each ASODN group, the effect above-mentioned has time- and concentration-dependent manner.

结果： 转染ASODN各组OS-732细胞survivin mRNA和蛋白表达均明显弱于空白对照组、SODN组；细胞凋亡率显著增加，细胞生长相应受抑，caspase-3活性显著提高；上述效应在ASODN各组存在一定的时间浓度依赖性；而SODN各组与空白对照组间各项指标均无明显差异。

Cable dampener cannot be rolled up but must be hung over the cable.

缆帆不能被卷起，必须保证处于展开状态

"This skylark is a present from my master," he says.

"这只云雀是我主人献上的礼物。"他说。