查询词典 laudanosine

The present study determined the effect of laudanosine on the minimum alveolar concentration of halothane and the influence of different inhaled anesthetics on the plasma concentration-seizure effect relationship for laudanosine in rabbits.

本文研究了Laudanosine在家兔中的药物代谢动力学及其对家兔氟烷MAC的影响，观察了几种常用吸入麻醉剂对家兔Laudanosine致惊厥血浆阈浓度的影响。

To determine the effect of anesthetic agents on the plasma concentration of laudanosine that produces seizure activity, the author administered laudanosine by i. v. infusion to rabbits with 7 different regimens.

家兔按Wagner氏双速率法静脉点滴Laudanosine溶液使血浆浓度达200，400，800ng/ml左右时，其氟烷MAC较对照（1.08±0.28%）分别增高8，22和30%左右，但无惊厥体征或脑电变化出现。

Plasma levels of atracurium and laudanosine were determined by high-performance liquid chromatography and the concentra- tion-time data were analized pharmacokinetically and pharma- codynamically with software package of MCPKP and Sheiner's principle respectively.

本文以高效液相色谱法测定血浆阿屈宁和Laudanosine浓度，分别以MCPKP软件和Sheiner氏药物效应学模型行药物代谢动力学和药物效应动力学分析。

Caco-2 cell monolayer ; papaverine ; laudanosine ; cepharanthine ; intestinal absorption ; apparent permeability coefficient

Caco-2细胞单层；罂粟碱； N-甲基四氢罂粟碱；头花千金藤碱；肠吸收；表观渗透系数

Although the clinical experience and the results of animal experiments indicate that the adminis- tration of atracurium at recommended doese is unlikely to result in laudanosine concentrations capable of producing seizure activity, Hennis et al found that at a plasma concentration below that causing convulsions, laudanosine "awaken"dogs lightly anesthetized with halothane.

临床病人应用常用剂量阿屈宁后，血浆Laudanosine选低于使动物发生惊厥所需的浓度，数百万例应用阿屈宁的病人中也未见有因代谢生成之Laudanosine而发生惊厥体征或脑电征象者。可以认为，阿屈宁的临床应用是不会因Laudanosine的生成而引起惊厥的。

Data of plasma concentration vs. time after an i. v. bolus dose of laudanosine could be fitted to a two-compartment pharmacokinetic model. Laudanosine infusion incereased halo- thane MAC values in rabbits.

家兔单次静脉注射Laudanosine后，其血浆浓度对时间关系符合开放型二室药物代谢动力学模型，各主要参数为〓，〓16.9min，〓，〓和Cl=41.9±6.7ml/kg·min。

But in the course of internationalization, they meet with misunderstanding and puzzlement.

许多企业已经意识到了这一点，但在国际化的进程中，仍存在一些误区与困惑。

Inorder toaccomplish this goal as quickly as possible, we'll beteamingup with anexperienced group of modelers, skinners, and animatorswhosenames willbe announced in the coming weeks.

为了尽快实现这个目标，我们在未来数周内将公布与一些有经验的模型、皮肤、动画制作小组合作。