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Methods selective and limited minimally invasive debridement under arthroscope was applied to 54 patients with osteoarthritis of knee joint; hyperplasia of inflammatory synovial membrane and abrasion of anterior cruciate ligament were chipped or vaporized with radiofrequency, the corpus liberum were taken out, cartilage was scoured into certain shape; excision or partial excision were performed to hyperplastic intercondyloid spine, osteophyma and menisci; intercondyloid fossa was formed.results 45 cases were followed up for an average of 18 months (from 6 months to 24 months); the clinical symptoms of most cases released obviously and the joint function improved.conclusions minimally invasive debridement under arthroscope can effectively release oa symptoms, improve joint function and raise the quality of life.

对54例膝关节骨性关节炎患者进行关节镜下选择性、有限化微创清理术。手术内容包括刨削或射频汽化增生的炎性滑膜组织和前交叉韧带磨损、游离体取出、软骨打磨成形、增生髁间棘切除、部分骨赘切除、半月板部分切除、髁间窝成形。结果随诊45例,平均18个月(6~24月),大多数患者临床症状明显缓解,关节功能改善。结论关节镜微创清理术可有效缓解oa症状,改善关节功能,提高生活质量。骨关节炎;膝关节;关节镜检查

Methods: 37 patients with complex upper urinary lithangiuria with pyonephrosis were selected during November 2002 to July 2007. 8 cases were treated with transurethral ureteroscope lithotripsy followed by tube internal drainage, while 29 cases were treated with minimally invasive percutaneous nephrolithotomy. After 714 days, minimally invasive percutaneous nephrolithotomy was employed for the second therapy.

选择2002年11月~2007年7月复杂上尿路结石合并脓肾患者37例,采用经尿道输尿管镜取石后置管内引流8例,微创经皮肾造瘘外引流29例,术后7~14 d后,2期行微创经皮肾镜治疗复杂肾结石。

Results There were three morphological types of BM metastasis of NB, microinvasive, moderately invasive and diffusely invasive pattern. CgA/NSE immunohistochemical staining was needed fur confirming the metastatic neuroblastic cells in microinvasion.

结果 神经母细胞瘤骨髓转移表现为微小浸润、中度浸润和弥漫浸润三种形式,主要根据骨髓造血组织与肿瘤成分的比例和分布而定,其中微小浸润常需行CgA/NSE免疫组化染色辅助诊断。

All the LOH on 〓 and 〓 was observed in invasive ductal carcino- ma, carcinoma simplex, medulary carcinoma and scirrhous carcino- ma, no deletions at these sites were observed in any invasive lobular carcinoma and others. These results imply an etiological difference.P53 gene is a hot point gene in the occurrence and development of breast, cancer. PCR-SSCP analysis was performed to detect P53 gene point mutation in the region between exon 5 and 8, 5 of 12 (41. 6%) stage I breast cancer patients contain mutation of P53, 3 of 5 patients were accompanied by 〓 deletion. These results suggested that point mutation and allelic loss of P53 gene are two vi- tal genetic events in earlier stage of breast tumorigenesis.

我们还发现,〓和〓位点LOH均分布在乳腺浸润性导管癌、单纯癌、髓样癌及硬癌中,在浸润性小叶癌和某些特殊类型乳腺癌中全部为LOH阴性,上述位点LOH可能与某些组织学类型乳腺癌的发生有关。P53基因是乳腺癌形成过程中的一个热点基因,本研究对12例Ⅰ期乳腺癌组织标本中P53基因热点区域第5、6、7、8外显子点突变进行了测定,发现41.6%(5/12)的病人有P53基因一个或多个点突变,其中3例同时伴有〓位点LOH,表明P53基因点突变和等位基因缺失是发生在乳腺癌形成早期的一个重要遗传学事件。

Methods: The method of immunohistochemistry was used to study the expression of CD44v6 protein in the cases, including 10 normal cervix, 15 dysplasia, 16 squamocellular carcinoma in situ , 1 adenocarcinoma in situ , 27 invasive squamocellular carcinoma, and 15 invasive adenocarcinom...

用免疫组化法检测 10例正常宫颈上皮、15例宫颈上皮不典型增生、16例宫颈原位鳞癌、1例宫颈原位腺癌、2 7例宫颈浸润鳞癌、15例宫颈浸润腺癌中CD44v6蛋白的表达,实验结果以图像处理与分析系统进行半定量处理后进行统计分析。

The invasive and migratory potential of M0 M and M cells in vitro and in viva were observed by Boyden chamber and by inoculation into nude mice and, simultaneously, correlation between the expression of Tiam 1 acid the invasive and migratory potential of gastric cancer cells was analysed.

应用裸鼠接种法观察M0,M,M细胞的在体成瘤及转移能力。

Ultrasound and scintigraphy are non-invasive methods used to detect urinary extravasation. Reconstructed CT ureteropyelography has also been employed for the detection of urinary extravasation after renal transplantation. MRI imaging can show the renal function of the transplanted kidney and the extravasation. MRI is an effective non-invasive alternative for the diagnosis of urinary extravasation after renal transplantation especially when ultrasound and scintigraphy are inconclusive.

超音波及核子医学检查是诊断肾脏移植后尿液外漏的非侵袭性的方法,MRI 可以明确的侦测尿液外漏,而且可以知道移植的肾脏是否有功能,这能决定是否需要及是否值得再一次手术,所以MRI 是另一个可以有效且非侵袭性检查,在超音波及核子医学检查没有明确诊断时,可以帮助诊断。

HIFU (High Intensity Focused Ultrasound) therapy system, is a non-invasive and minimally-invasive device recently developed for clinical treatment of tumors. Ultrasound beams from an extracorporeal transducer penetrates the overlying tussue, and then focuses on and ablates the target tumor within the body.

高强聚焦超声刀(High Intensity Focused Ultrasound, HIFU),是一种新型的现代无创、微创治疗高科技设备,通过体外照射治疗机体内部实体肿瘤。

Subsequent surgical excisions were available in 20/33 pure FEA and in 10/11 FEA+ADH: of the 20 patients with pure FEA on CNB, none had either ductal carcinoma in situ or invasive carcinoma in their excisional biopsy, whereas 3/10 (30%) FEA+ADH on CNB showed, at subsequent surgery, more advanced lesions (2 ductal carcinoma in situ, 1 invasive carcinoma).

我们得到了20/33例单纯性FEA和10/11例FEA+ADH随后的大体手术切除资料:20例单纯性FEA大体切除标本中,无一例发现有导管原位癌或浸润性癌;而那10例FEA+ADH的大体标本中有3例(30%)发现高级病变(2例导管原位癌、1例浸润性癌)。

Treating tibial plateau fractures with MIPO has little obstructe in environment of fracture healing through minimally invasive,has fortes of minimally invasive,firm of internal fixations,low rate of infection,high rate of fracture healing,can reduce the complications,fit principle of biologic fixation.

MIPO在治疗胫骨平台骨折时以微创来提供尽可能少受干扰的骨折愈合环境,具有创伤小、固定确实、感染率低、骨折愈合率高等优点,减少了并发症的发生,符合生物学固定的原理。

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