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The results showed that methamidophos inhibited the growth and activity of bacteria, Actinomyces and Azotobacter at different degree, but stimulated the growth of fungi; the results also showed that soil respiration and ammonification was stimulated, however, soil nitrogen fixation, nitrification and Fe-reduction was inhibited.

结果表明,甲胺磷对细菌、放线菌和固氮菌群的生长具有不同程度的抑制作用,而对真菌却有一定的刺激效应;土壤的呼吸作用、氨化作用增强,自生固氮能力、硝化作用以及铁离子价数转换作用减弱。

The pH value in soil was significantly increased in litter aqueous extract of four decomposition stages. The NH+4-N concentration was significantly decreased in soil amended with litter aqueous extract of 10-day decomposition which promoted the growth of Aerobic azotobacter and Ammonifier but inhibited the growth of Aerobic cellulose-decomposer. Available phosphorus concentration was significantly increased and phenolic acid content was significantly decreased in soil amended with litter aqueous extract of 60-day decomposition which inhibited the growth of Aerobic azotobacter but promoted the growth of Aerobic cellulose-decomposer.

不同分解时间的凋落物浸提液均造成了土壤pH值的显著升高;分解10d的凋落物浸提液对土壤铵态氮的含量具有显著的降低作用,对土壤好气性自生固氮菌和氨化细菌的生长均具有显著的促进作用,而对好气性纤维素分解菌的生长具有抑制作用;分解60d的凋落物浸提液显著地降低了土壤酚酸含量,对土壤有效磷含量具有显著的升高作用,对好气性自生固氮菌的生长具有抑制作用,而对好气性纤维素分解菌的生长具有促进作用。

The antibacterial activities of most of fractions were similar to the pomegranate peel extract.(7) Respiratory inhibition experiment showed that the respiration of thallus was inhibited mainly through the hexose monophosphate pathway, which leaded to be short of NADPH, and induced metabolic function dysfunction. Growth curve assay showed that the pomegranate peel extract inhibited cytodieresis in logarithmic growth phase. After exposure to the pomegranate peel extract, bacterial protein was analyzed by SDS-PAGE. The results showed that protein synthesis was inhibited, especially for large molecular weight protein.

7呼吸抑制试验结果表明,石榴果皮提取物主要是通过抑制HMP途径,导致还原力NADPH缺乏,引起代谢功能障碍,达到抑菌的目的;加药组和正常组金黄色葡萄球菌生长曲线的对比结果表明,石榴果皮提取物能够抑制金黄色葡萄球菌对数生长期的菌体分裂;SDS-聚丙烯酰胺凝胶电泳分析表明,石榴果皮提取物能够抑制菌细胞蛋白合成,尤其对菌体内大分子量蛋白作用最明显。

The effect of genistein (0.8 mg/kg) was partially inhibited by L-NAME, or by sodium orthovanadate (50 μg/kg), a potent inhibitor of protein tyrosine phosphatase;(2) genistein also decreased the PP of renal vascular bed in a dose-dependent manner and the effect of genistein was completely inhibited by pretreatment with sodium orthovanadate, but unaffected by L-NAME; and (3) genistein decreased the PP of mesenteric vascular bed in a dose-dependent manner, an effect which was partially inhibited by sodium orthovanadate, but unaffected by L-NAME.

GST的这一效应可被L-硝基精氨酸甲酯部分阻断,预先注射蛋白酪氨酸磷酸酶抑制剂正钒酸钠(50 μg/kg),可部分抑制GST (0.8 mg/kg)引起的效应;(2)向肾血管灌注环路中直接注射 GST 也可剂量依赖性地降低肾动脉的灌流压,预先注射正钒酸钠可完全抑制GST引起的效应,而L-NAME对此效应没有影响;(3)肠系膜血管灌流环路中注射GST可剂量依赖性地降低其灌流压,这一效应可被正钒酸钠部分抑制,而L-NAME对此无影响。

The effect of genistein (0.8 mg/kg) was partially inhibited by L-NAME, or by sodium orthovanadate (50 μg/kg), a potent inhibitor of protein tyrosine phosphatase;(2) Genistein also decreased the PP of renal vascular bed in a dose-dependent manner. The effect of genistein was completely inhibited by pretreatment with sodium orthovanadate, but unaffected by L-NAME;(3) Genistein decreased the PP of mesenteric vascular bed in a dose-dependent manner, an effect which was partially inhibited by sodium orthovanadate, but unaffected by L-NAME.

GST的这一效应可被L-硝基精氨酸甲酯部分阻断,预先注射蛋白酪氨酸磷酸酶抑制剂正钒酸钠(50 μg/kg),可部分抑制GST (0.8 mg/kg)引起的效应;(2)向肾血管灌注环路中直接注射 GST 也可剂量依赖性地降低肾动脉的灌流压,预先注射正钒酸钠可完全抑制GST引起的效应,而L-NAME对此效应没有影响;(3)肠系膜血管灌流环路中注射GST可剂量依赖性地降低其灌流压,这一效应可被正钒酸钠部分抑制,而L-NAME对此无影响。

The HE activity was almost completely inhibited by SBTI, p-APMSF, bestatin and NEM, greatly inhibited by ovomucoid, TLCK, IAM, chymostatin and PMSF, and slightly inhibited by pepstatin A, TPCK, LBTI and leupeptin. And these results imply that HE is most probably a trypsin-type serine protease.

抑制剂对其酶活性的影响结果显示,该孵化酶的活性几乎可被SBTI、p-APMSF、Bestatin和NEM所完全抑制,被ovomucoid、TLCK、IAM、chymostatin和PMSF所强烈抑制,而对pepstatin A、TPCK、LBTI和leupeptin不敏感,表明该酶极可能是一种属于胰蛋白酶类型的丝氨酸蛋白酶。

The results showed that the activities of extracellular pectin methyltrans-eliminase, pectinase, extracellular C1 and proteinase were activated by asarum essential oils; the activities of pectin methylgalactuionase and intracellular C1 were activated at first, then inhibited and activated again; the activities of intracellular pectin methyltrans-eliminase were mostly inhibited; the activities of Cx were entirely inhibited by asarum essential oils, the percentage of inhibition was in proportion to the asarum essential oil concentration.

结果表明:辽细辛精油对胞外PMTE酶、果胶总酶、胞外C1酶和蛋白酶表现为激活作用,对PMG酶和胞内C1酶则表现为先激活后抑制再激活作用,对胞内PMTE酶主要表现为抑制作用;对Cx酶表现为完全的抑制作用,且酶活抑制率与精油浓度成正比。

RESULTS:(1) ET-1 could increase total protein production, surface area, ERKs activity and [Ca2+]i in cultured cardiomyocyte in dose-dependent manner at concentrations ranging from 10-9 to 10-7 mol/L. And this effect could be abolished by BQ123, an antagonist of ETA receptor, partly inhibited by PTX, but not by BQ788, an antagonist of ETB receptor.(2)The activation of ERKs and the increase of [Ca2+]i induced by ET-1 were obviously inhibited by PD98059, a selective ERKs kinase inhibitor, and nifedipine, a calcium channel blocker, respectively. Both antagonists partially inhibited ET-1-stimulated cardiomyocyte hypertrophic response.(3) Staurosporine, a selective PKC inhibitor, could inhibit ET-1-stimulated cardiomyocyte hypertrophic response and increase of [Ca2+]i, but not affect the activation of ERKs.

结果: ①ET-1浓度依赖性增加新生大鼠心肌细胞蛋白质含量和心肌细胞表面积、ERKs活性及[Ca2+]i浓度,以上作用可被ETA受体拮抗剂BQ123所完全抑制,被百日咳毒素部分抑制,而ETB受体拮抗剂BQ788则无效;②ERKs激酶特异性抑制剂PD98059可完全抑制ET-1激活ERKs的作用,钙通道拮抗剂硝苯地平可明显抑制ET-1介导的[Ca2+]i浓度增加,但二者皆仅部分抑制ET-1介导的心肌细胞肥大反应;③蛋白激酶C选择性抑制剂staurosporine并不能明显抑制ET-1介导的ERKs激活,但可抑制ET-1介导的的[Ca2+]i浓度增加及心肌细胞肥大反应。

Cd inhibited the absorption of Mg and Mn in roots. However, Cd could stimulate the absorption of Fe in roots. Moreover, Cd inhibited the absorption and utilization Mg, Mn and Fe in leaves. 4. Cd inhibited the photosynthesis of Populus clones. Cd showed no significant inhibition to net photosynthesis rate, stomal conductivity and transpiration rate versus the control, under 10μM Cd treatment.

Cd胁迫还对杨树光合作用产生影响,低浓度Cd对杨树光合速率无影响,中高浓度Cd对杨树净光合速率、气孔导度和蒸腾速率等具有抑制作用,而且随着处理时间的延长和Cd胁迫浓度的提高而逐渐加大。

Hexokinse is inhibited by glucose 6-phosphate which builds up after PFKis inhibited.Pyruvate kinase is activated by fructose 1,6-bisphosphate but allosterically inhibited by ATP and alanine. Like PFK,it is also regulated hormonally by glucagon.

己糖既没被 PFK 受到抑制后积累的葡萄糖 6-磷酸激活,但受到 ATP 和丙氨酸的别构抑制;像 PFK 一样,它也受到胰高血糖素的调节。

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He is the most remarkable man that I have ever known.

他是我知道的人中最值得注意的人。

Increased appearance of lymphocele was noticed in patients with diabetic nephropathy, congenital malformations of the urinary tract, and inflammatory diseases, including glomerulopathy and extraglomerular ones, after high-voltage radiotherapy and after removal of the renal graft.

经过高压放射疗法和切除移植肾后,在糖尿病肾病患者、泌尿系统先天性畸形患者和炎症患者身上发现淋巴囊肿有所增加,包括肾小球病和球外疾病等。

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