查询词典 inhibit from

Result: It has been found out that the fat-soluble nonsaponified extract from Temminck et Schlegel and the alcoholic extract from Syngnathus acus have cytotoxic activities.The nonsaponified extract from Temminck et Schlegel can inhibit the grouth of cancer cell strains KB,Hela,PAA,K562,and Bcap37,and the alcoholic extract from Syngnathus acus can inhibit the growth of cancer cell strin KB,But Bloch shows no apparent anticancer activity.

结果：尖海龙的95%乙醇提取物对KB细胞的生长具有抑制作用，并呈量效关系；粗吻海龙的脂溶性非皂化物具有不同程度的抑制人癌细胞株KB，Hela，Bcap37，K562，PAA细胞的作用，并有明显的量效关系；拟海龙的各提取物未见有明显的抑制肿瘤细胞生长的作用。

And Bauhinia purpurea could inhibit vibrio. And the extracts, extrated with petroleum ether from leaves of Melia azedarach L. and Bauhinia purpurea can inhibit Vibrio parahaemolyticus, too. The remainder extracts of Mangifera indica Linn.showed strong inhibition effect on Vibrio tubiashii. While the extracts of Eriobotrya japonica showed no inhibition effect.

结果 夹竹桃叶、芒果叶、苦楝叶和羊蹄甲叶4种中草药乙酸乙酯萃取部分对供试弧菌有很好的抑菌作用；苦楝叶和羊蹄甲叶石油醚萃取部分对副溶血弧菌有抑菌作用；芒果叶的水溶性部分对塔氏弧菌有很强的抑菌作用；枇杷叶提取物对4株弧菌均无抑制作用。

Parthenolide is extract from feverfew, it's main component is sesquiterpene, it is commanly used in west country and is mainly used to therapy skin infection, rheumatic disorder, migraine. But recent research indicate that parthenolide can regulate many pathway of signal in the cell, inhibit the cyclooxygenase, TNF-α, interleukin-1 expression induced by lipopolysaccharide in macrophage, inhibit the iNOS expression in human monocyt, inhibit the activity of NF-κB in Hela cell, inhibit the growth of tumor cell and can relieve the myocardial ischemical reperfusion injury and so on. But the invention research about the effection of parthenolide on the VSMC is very rare in the world, so we do some research about the effection of inhibition of parthenpolide on the proliferation of VSMC and the signal transduction mechanism.

小白菊内酯(parthenolide，又名Sesquiterpene lactone)是艾叶菊属黑叶母菊的提取物，主要成分是倍半萜烯内酯，西方国家较为常用，主要用于治疗皮肤感染、风湿病和偏头痛，但近年来发现小白菊内酯能调控细胞内多种信号途径，如抑制巨噬细胞中脂多糖诱导的Cox，肿瘤坏死因子α和白细胞介素-1的表达，能抑制人单核细胞中iNOS的表达，能抑制Hela细胞中NF-κB的活性，抑制肿瘤细胞的生长，同时能减轻心肌缺血再灌注损伤等，但小白菊内酯在VSMC中的干预研究目前国内外非常罕见，为了确切评价小白菊内酯对血管平滑肌细胞增殖的抑制作用及相关的信号转导机制，我们进行了一些研究。

Wenxin capsule can promote endolethial cells releasing CO and synthesing 〓, enhance activity of HO, induce angiectasis through activating guanylic cyclase and adenglate cyclate of intracellar of vessel smooth muscle cell to enhance content of intracellar cGMP and AMP. 3. Wenxin capsule can inhibit releasing of platelet activiting factor 〓 which inhibit platelet aggregation and have antithrombosis function. 4. Wenxin capsule can promote activity of t-PA, reduce activity of PAI-1, strengthen fibrinolytic function, therefore inhibit fibrin disposition. 5. Wenxin capsule can inhibit synthesis of smooth muscle cellular DNA. Its function don't kill it directly but prevent transformation from period Go to peried S. 6. Wenxin capsule is an effective prescription of anti-coronary atherosclerosis atherosis. The results of image pattern analysis tastifies that area of lipid plaque in treating group reduce 54% and 58% in contrast with that in control group. The results of light, electro- microscopy show that structure of endolethial cell and smooth muscle cell in treating group is more integral than that in control group.

其作用机制之一是由于该药具有良好的调脂降脂作用，其不仅能明显降低血清LDL-c及升高HDL-c含量，且能有效阻止TC沉积于血管壁，从而保护内皮细胞结构完整；此外，温心胶囊尚具有明显的抗氧化作用，该药不仅能明显降低血浆LPO含量，且能提高SOD活性，同时其对血红素在细胞内代谢的调节作用也参与了抗氧化过程。2 温心胶囊能明显促进内皮细胞释放CO及合成〓，提高HO活性，通过激活血管平滑肌细胞内鸟苷酸环化酶及腺苷酸环化酶引起细胞内cGMP、AMP浓度增加而引起血管舒张。3 温心胶囊能明显抑制血小板激活因子〓的释放，从而抑制血小板聚集，抗血栓形成。4 温心胶囊能明显提高t-PA活性，降低PAI-1活性，增强纤溶功能，从而抑制纤维蛋白沉积。5 温心胶囊能明显抑制平滑肌细胞DNA合成，其抑制作用不是直接杀伤抑制，而是阻止细胞由Go期向S期转化。6 温心胶囊是抗冠状动脉粥样硬化的有效制剂，图象分析结果证实，该药治疗组脂斑面积比对照组缩小了54％和58％，光电镜结果显示内皮细胞及平滑肌细胞结构较为完整。

Research for the antiseptic and fresh-keeping technique indicates that, the 500-fold antiseptic of 75%Tuobujing can effectively inhibit Dothiorella ribis from growing and the 200 mg.L-1 antibiotic of Qingdameisu and 160 mg.L-1 strepotmycin can effectively inhibit Pesudomonas vesicularis from growing.

防腐保鲜措施的研究表明，杀菌剂以75%托布津500倍液抑制多主小穴壳菌生长的效果最好，抗生素以庆大霉素2 000 mg/L和链霉素160 mg/L抑制泡囊假单胞杆菌生长效果最好。

With 〓H-TdR incorporation and cell count, we found that AdM could inhibit DNA synthesis and the proliferation of VSMCs from SHR. With semiquantitative RT-PCR analysis, we found that AdM mRNA level was lowerer in kidney and VSMCs from SHR than those from WKY.

应用〓H-TdR掺入和细胞计数发现，AdM可以抑制培养的自发性高血压大鼠VSMCs的DNA合成和细胞增殖；应用半定量RT-PCR分析发现，在自发性高血压大鼠的肾和VSMCs中，AdM mRNA水平较低。

Results:(1) FSN can inhibit secondary joints swelling and multi-arthritis evidently, improve the whole condition of rats; at the same time, it can also lighten the synovial inflammation and hyperplasia of lesion joints distinctly, and prevent the joint cartilage and bone from destruction; the collective efficiency of FSN is better than TWP.(2) FSN can raise AA rats low LTT of spleen to normal nearly, remedy the disorder of Th / Ts and Thl / Th2 cells balance in peripheral blood, restrain exorbitant TNF- a ? IL-1 produced by PM O , thereof exert anti-inflammatory and immunoregulation effect.(3) Inside the lesion joints, FSN can depress abnormal hyper-expression of TNF- a mRNA and NF-kB in synovial tissues, as well as advance the expression of Caspase-3 (a proteolytic enzyme of apoptosis), reduce synovial immflamination and proliferation.(4) FSN can lower the expression of VEGF in synovial tissue,reduce neogenetic veins, so inhibit the growth of pannus tissue and the damage of cartilage and bone by that.(5) The above effect of FSN are in proportion to its dosage.Conclusions: FSN has inhibitory effects on symptom and condition of experimental RA, which is better than TWP as a whole.

结果：(1)FSN有明显的抗炎作用，可显著抑制AA大鼠足跖肿胀与多关节炎，改善大鼠的全身情况，同时明显减轻病变关节滑膜炎症与增生，防止关节软骨及骨质的破坏，其综合作用优于TWP；(2)FSN还能使AA大鼠低下的脾LTT恢复至接近正常，纠正外周血中T细胞亚群Th／Ts及Th1／Th2平衡紊乱，抑制大鼠PHφ过高的TNF-α、IL-1分泌，而发挥抗炎和免疫调节作用；(3)在病变关节局部，FSN能显著抑制AA大鼠滑膜细胞异常增高的TNF-αmRNA的表达，降低滑膜组织中NF-kB表达，并增加凋亡蛋白酶Caspase-3表达，从而抑制滑膜的炎症与增殖；(4)FSN还可下调滑膜组织中VEGF表达，减少血管新生，由此抑制血管翳的形成及其对软骨和软骨下骨的侵蚀；(5)FSN的上述作用皆呈现一定的量效依赖关系，高剂量组作用优于低剂量组。

Deduced by the proportion of typical sterile plants and normal fertile plants in segregative generations derived from WA zhenqiuA/6078 that:I gene could inhibit the expression of Rf gene completely by the heterozygosity of 1 pair of Rf in genotype;and only reduce the expression of Rf genes with two heterozygous Rf genes in genotype ;but it would never inhibit the expression of Rf genes if the genotype included 3 pairs of heterozygous Rf genes. When Rf gene was homozygous,the / gene could not inhibit the expression of it.

根据认叭真秋刀6078各衍生分离世代中典型不育株和正常可育株所占比例推断：基因型中仅包含1对杂合的Rf基因时，I对Rf的表达起完全抑制作用；基因型中包含2对杂合的Rf基因时，I仅对Rf的表达起削弱作用；当基因型中包含3对杂合的对基因时，I对Rf的表达不起抑制作用；I对纯合位点的Rf的表达不起抑制作用。

CO2 can inhibit the proliferation and promote the apoptosis of the endometrial cancer cells with distending pressure from 40 mmHg to 100 mmHg. The higher the pressure is, the more obviously CO2 can inhibit the proliferation and promote the apoptosis of the endometrial cancer cells.

二氧化碳在40~100 mmHg压力范围内，能够抑制子宫内膜癌细胞的增殖，促进子宫内膜癌细胞的凋亡，且随着压力的增加，二氧化碳对子宫内膜癌细胞增殖抑制和促进凋亡作用愈明显。

The infectivity of TMV recovered by dialysis from incubation with anthraquinone glycosides in vitro has been reduced in contrast to infectivity of TMV control, it seems that anthraquinone glycosides have direct viricidal effect on TMV. The anthraquinone glycosides may interfere recognization of TMV to host receptor when applied before TMV inoculation. The anthraquinone glycosides can inhibit multiplication of TMV in infected leaf discs but did not inhibit infectivity of TMV-RNA in vitro. The control of tobacco mosaic virus disease of N.

总蒽醌甙对TMV混合，对粒体形态无破坏作用，但经透析，其抑制作用仍较高，表明总蒽醌甙与TMV结合能力强不易解离或对粒体具有直接毒害作用；总蒽醌甙预先接种可能影响病毒对侵染位点的识别，对叶圆片中的病毒具有抑制复制的作用，但在体外混合不影响TMV-RNA的侵染活性，可能与总蒽醌甙干扰病毒的衣壳装配过程或影响复制酶的活性有关。

Objective: To study the effect of polycythemia on blood oxygen saturation.

裴蕾目的：观察RBC剧增而引起的高粘血症对血氧饱和度的影响。

Based on SIMPLER algorithm in the curvilinear body-fitted coordinates, the calculations were performed for Pr=0.7, Re=10~1000 on non-orthogonal non-staggered grids which are generated by elliptic equation systems.

采用曲线坐标系下压力与速度耦合的SIMPLER算法，数值研究了周期性渐扩渐缩波纹通道内脉动流动与换热情况，流动Re数的范围为10~1000，Pr数为0.7。