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Method］twelve cases with extremities invasion bone tumor were reviewed,including 6 male and 6 female.the average age was 37.1 years old.according to the mri,typeⅰtumor located in metaphysic and growth eccentricity,and was treated with outside tumor osteotomy with reservation of one side as integumentale,the cut line was shape of "匚".type ⅱ tumor was with invasion part articular surface,and was operated with part joint osteotomy with reservation of one side as integumentale,the cut line was shape of"l".type ⅲ was with invasion total joint surface and as integmentale,all tumor segment including joint could be cut,but the shape of cut close to the diaphysis was echelonment.

方法］12例侵袭性骨肿瘤患者男6例，女6例；平均年龄37.1岁。根据mri表现选择不同截骨方法，ⅰ型肿瘤位于干骺端偏心性生长，采用保留一侧皮质骨的肿瘤外截骨，截骨线呈&匚&形。ⅱ型病例肿瘤侵蚀部分关节面，采用保留一侧皮质的部分关节截骨，截骨线呈&l&形。ⅲ型病例肿瘤侵蚀整个关节面和骨皮质，可切除包括关节在内的整个瘤段骨，只是近骨干侧截骨呈阶梯状。

The company built up three rim producing lines newly (including one rolled wheel rim producing line), one disc producing line, one spring circle producing line, two raw material cutting-off lines, one cathodic electrocoating line and one face-painting line, The company's porducing capacity is 2.6 million suits of wheels including 2 million suits of section steel wheels and 6 hundred thousand suits of rolled wheels.

滚型车轮生产线引进了当今世界最先进的关键设备和工装（轮辋生产线由荷兰 Fontijne 公司提供、轮辐旋压机由德国 WF 公司提供、检测设备由德国 Hafner 公司提供），吸收和掌握欧洲一流车轮生产厂家（如德国的 Lemmerz 、意大利的 Gianetti 和 FAD 等）的技术和工艺。

The body of this thesis is divided into four parts: Part One relates basic theories concerning judge's elucidatory authority, including its implications and character, its relationship with arguement-orientedness, and its value; Part Two introduces rules and regulations about judge'elucidatory authority in different countries in the hope for our country to draw lessons on; Part Three analyzes the present legislation situation of judge's elucidatory authority, emphasizing some existing drawbacks and necessity of constructing judge's elucidatory authority in our country; Part Four puts forward some suggestions on the content of judge's elucidatory authority to be constructed in our country, including five aspects of its fulfilling principles, fulfilling methods, fulfilling phases, legal effect and restraining mechanism.

正文可分为四个部分。第一部分是对释明权理论基础的研究，包括释明权的含义和性质，释明权和辩论主义的关系以及释明权的价值；第二部分介绍了各国关于释明权的法律制度，以期能为中国制度构建提供参考借鉴；第三部分分析了我国关于释明权的立法现状，着重分析了立法上存在的缺陷并论证了建构并完善我国法官释明权制度的必要性；第四部分对我国法官释明权制度内容的构建提出建议，包括释明权的行使原则、行使方式、行使阶段、法律效力以及约束机制五个方面。

The hypermethylation of 5 CpG in promoter region serves as a mechanism of the inactivation of RASSF1A gene. This mechanism has been widely confirmed in multiple tumorgenesis including prostate carcinoma cell line DU145. Object Our study is to disclose the epigenic mechanism of the carcinogenesis of prostate cancer. Including: 1. We use demethylation agents in combination with chemotherapeutic drugs, to disclose whether demethylation agents can enhance the anticancer effect of chemotherapeutic drugs. 2. to study whether demethylation drugs can affect the methylation level of RASSF1A gene in.

目的 本研究旨在探讨前列腺癌的表遗传学发生发展机制，包括： 1、甲基化抑制剂与多种化疗药物联合应用，探讨二者间的协同作用，增强化疗药物疗效； 2、体外应用甲基化抑制剂对前列腺癌细胞DU145的RASSF1A基因甲基化水平的影响； 3、体外应用甲基化抑制剂对前列腺癌细胞DU145的RASSF1A基因及蛋白表达的影响，以期为进一步深入探索通过改变抑癌基因的甲基化而为前列腺癌发生机制和基因治疗提供有意义的数据和理论依据。

Methods Tweleve healthy SD rats were cauterized three episcleral vessels and were divided into two groups (tPNS treated group including normal IOP and elevated IOP, untreated group including simple normal IOP and elevated IOP)with 6 rats in each group.

健康SD大鼠12只，采用Akira法，烙闭大鼠右眼上巩膜静脉，制作大鼠持续性高眼压模型，随机分为对照组，tPNS治疗组。

The structure of this article is as follows: Firstly, the background of this article is stated in exordia and the question was raised; chapter one stated cash flow management theory and transnational corporations' cash flow management characters; chapter two introduced general cash flow management technical and method; chapter three analysis cash flow management situation of Chinese transnational corporations; chapter four take VW as an example to expatiate company situation and the impact to cash flow management by the organization of the company, the goal of cash flow management and financing strategy, then introduce the cash flow forecast module, at last analysis the experience and disadvantage of VW's cash flow management; Chapter five give some suggestions to Chinese local transnational corporations for cash flow management including: using proper cash flow management technical and establish scientific process, ect.; the last part is the conclusion This article took VW's cash flow management as an example to descried transnational corporation cash flow management theory and practical issues, but some techniques can only be used in some country where can exchange currency freely; it can not be practical in some foreign exchange administration countries including China, such kind of cash flow module still under discussion based on theory.

本文结构如下：首先在绪言部分简述了选题背景，提出了问题；之后，第一章陈述了现金流管理理论和跨国公司现金流管理的特点；第二章评述了国际常见的现金流管理技术和方法；第三章分析了中国跨国公司的现金流管理现状；第四章详细阐述了VW公司现金流管理的实例，包括公司的发展及组织架构设置对现金流管理的影响，公司现金流管理的目标、筹资策略等，重点介绍了VW公司的现金流预测模型，最后分析了VW公司现金流管理的经验和不足；第五章详细阐述了对中国跨国公司现金流管理的建议，包括应用适合的现金流管理技术及建立科学的现金流管理流程等；最后在结论部分对该文做了总结。

During the past decade, considerable research effort has been directed towards the development of in situmetal matrix composites, in which the reinforcements are formed in situ by exothermal reactions betweenelements or between elements and compounds. Using this approach, MMCs with a wide range of matrix materials(including aluminum, titanium, copper, nickel and iron), and second-phase particles including borides, carbides

在过去的几十年中，对于金属基复合材料我们做了大量的研究工作，这些复合材料的增强体都是通过元素之间或者元素与化合物之间的原位放热反应而加入到基体中的，这种方法广泛应用在生产金属基体材料（包括铝、钛、铜、镍和铁）和第二相颗粒中（包括硼、碳、氮、氧和他们的混合物）。

Four chapters in the first volume, including "The Origin of Movement","Thinking of Effort","Movement Space" and "To Find Body", develop the theoretical structures of body language in western modern dance, analyze elements of movements and their semantic characters, reveal the conceptual transformation in the science of modern human movements and science of body language, and discover the re-interpretation through modern dance about the essence of movement and space and time of movement Another four chapters in the second volume including "Feminized Body""Masculine Body""Sex-confused Body" and "Body's Origin", study respectively features of body language in the field of ballet, modern dance and post-modern dance, provide a chronicle embodying the form variation of body language through lineal comparison, and exposit spiritual pursuit and value preference of modern choreographers and their relationship with history and culture. Therefore, effective body strategy of "Back to Body's Origin" in today's human existence is offered and teaches us how to keep our own national culture in the times of cultural globalization and integration.

前者通过&动作的根源&、&力效思维&、&运动空间&、&发现身体&等4章，展开西方现代舞身体动作语言的理论构架，分析其动作语言要素和语义特征，揭示现代人体动作科学与身体语言科学的观念性变革，发现现代舞蹈对动作本质、运动空间和时间所做出的重新阐释；后者通过&女性化的身体&、&男性化的身体&、&性倒错的身体&及&身体的原点&等4章，研究芭蕾舞、现代舞、后现代舞的身体动作语言形态的各自特征，在纵向比较中，提供身体语言形态的&体现&变异的历史图表，在舞蹈本文的叙述和重新阅读中，提示现代舞蹈家的精神追求与价值取向，揭示其与历史文化之间的对应关系，提供现时代人类生存中所应采取的有效的身体策略——返回身体的原点，在全球文化大交流、大融合之中，保持民族文化的独立品格。

Now it is used in many branches in our nation including the department of agriculture, foresty, national resources , city construction and so on.Some of the existed national control networks of different precision rate or local areas based on the traditional surveying methods have played an important role in our national lives at the large costs including manuals, fianances and materials.

利用常规大地测量方法布设的各级国家大地控制网和以此为基准布设的各级地方控制网或地方独立网，是结合当时我国最高测绘技术水平，在花费了大量的人、财、物的基础上，建立的重要基础性测绘资料，为我国国民经济发展和社会各项建设事业发挥了重要作用。

The transforming growth factor-β superfamily, a large group of highly conserved growth factors including TGF-βs, activins and BMPs, regulate a wide variety of cellular functions such as proliferation, differentiation, apoptosis and migration. Signals from these growth factors are transduced by a group of Smad proteins. To date, there are nine vertebrate Smads, including the receptor-activated Smads , Smadsl-3, 5 and 8, the common mediator Smad4 and Smad4β, and the inhibitory Smads, Smad6 and 7. Signaling is initiated when the ligand induces assembly of a heteromeric complex of type Ⅱ and type Ⅰ TGFβ receptors. Then R-Smads are directly phosphorylated by activated type I TGF-β receptors.

在多种SMADS中，SMAD5令我们产生兴趣，基于三个原因：1、Smad5基因敲除胚胎中发现卵黄囊的异位造血以及CFU-GM祖细胞数目增加，表明SMAD5可能是早期造血发育的负向调控基因。；2、应用反义核酸封闭Smad5可以逆转TGF-β对祖细胞增殖的抑制效应，表明它可能介导TGF-β信号转导，后者的异常，包括某些SMADS的功能异常，和白血病紧密相关；3、Smad5基因定位在人染色体5q21，此区域的缺失和急性髓系白血病和骨髓增生异常综合症相关，因此，Smad5被怀疑为白血病抑制基因。

He became prime minister in 1997 and won international acclaim for his role in the Northern Ireland peace process.

他在1997年成为总理，并且因为在北爱尔兰的和平进程中发挥的作用受到国际社会的赞许。

Mixed Page Sorting Method Using the cuttable user model, this thesis proposes a mixed page sorting method by using cutted user model in server-side and complete user model in client-side.

隐私分级利用的混合式页面排序方法针对个性化搜索中搜索结果排序的问题，本文利用隐私可控开放的用户偏好模型，提出一个在客户端和服务器端分步进行的隐私分级利用的混合式页面排序方法。