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Hes5 gene, a key downstream mediators of Notch signaling that functions by inhibiting the expression or activity of positively acting bHLH factors, is a member of bHLH transcription factor family which acts as a positive-negative transcriptional regulators which is expressed transiently in different stages in cells growth and differentiation and orchestrate those precisely timed and progressive maturational events underlying cell fate decisions according to orders of time and spatial and coordinated the function of majority of signaling transduction on target genes to influence the proliferation and differentiation.

Hes5是Notch通路转导途径的一个关键的下游信号分子，通过抑制正调控bHLH因子的表达和活性来发挥作用，隶属于碱性螺旋-环区-螺旋转录因子家族。该家族形成一个正负转录调节器，按时空顺序短暂表达于细胞发育分化的不同阶段，介导和协调多种信号系统对大量靶基因的作用，影响细胞增殖、分化。

Appearance IdeaPad V450 and use the whole design, steady inward-looking, light weave texture top treatment, ability to handle and very good resistance to linear outline of the main fuselage section, simple smooth, the screen area aircraft using standard 14-inch widescreen LED screen above the built-摄象头of 1.3 million, in addition, it also supports the safe use of the face recognition function, a key to quiet mode, electrostatic induction multimedia touch operation, Entertainment Shuttle sound field control, Bluetooth and other rich attachments.

外观上IdeaPad V450运用全黑的设计，沉稳内敛，顶盖采用光织纹理处理，手感和抗压能力都非常出色，以直线条为主勾勒的机身，简洁流畅，屏幕方面，该机采用标准的14寸LED宽屏，屏幕上方内置130万的摄象头，此外，该机还支持安全易用的人脸识别功能，一键安静模式，静电感应式多媒体触控操作，娱乐飞梭音场控制，蓝牙等丰富的附件功能。

The dissertation analyzed the characteristic of the development of new high-tech industry at first. It pointed out that having characteristics such as high innovation and high risk, decides that the development of new high-tech industry needs the interference of government. Then, it analyzed the relevant theory of government economic functions and the particularity of the study during the development of new high-tech industry, pointed out the new high-tech industry even needs moderate interferes and supports of government. After that, draw lessons from the analysis train of the "diamond" theory of Michel Porter, it analyzed the demands of the development of new high-tech industry from the angle of catching up, include the regulation function that the key element disposes, demand regulation and preferential policy, strategical planning and organization coordinates, new high-tech enterprise hatches, and the supply of the legal system. Then it carried on international comparative analysis to the government economic functions of some typical countries, to find out the successful experiences with the lessons of the failure.

第一部分分析了高新技术产业发展的特点，指出高投入、高风险及高收益的特点决定了高新技术产业的市场失灵程度较高，且具有一定的公共物品的性质；第二部分分析了一般意义上的政府经济职能的内涵及相关理论，认为高新技术产业更需要政府的适度干预和支持；第三部分借助迈克尔·波特&钻石&理论的分析思路，分析了高新技术产业对政府经济职能的需求，即在要素配置、需求调节、战略规划和组织协调、孵化环节及法律制度方面需要政府的特殊支持；第四部分，对高新技术产业发展中政府经济职能的供给进行了国际比较和评价，探求各国实践中的成功与失败，并对理论分析进行了检验；第五部分对我国发展高新技术产业过程中政府发挥经济职能提出了几点启示。

During the lateral parabolic profile was computed,numerical methods of calculating angle of inclination on initial point of the lateral paracurve and calculating angle of inclination based on interval length were analyzed.It is pointed out that the key of the lateral parabolic profile design is a circular function equation which can be applied to solving the angle of inclination on initial point of the lateral paracurve.

对侧位抛物线剖面设计求解过程中的求侧位抛物线初始点井斜角的数值方法和从段长求井斜角的数值方法进行了分析，指出其关键是求解侧位抛物线初始点井斜角所满足的一个三角函数方程。

As a diatonic chord that the altered chords even do not belongs to the key, but it can not change the tonality, its function is to strengthen the harmony tension, enrich the harmonic color, and describe the music figures.

内容提要：变和弦作为不改变调性的非本调自然音的和弦，是音乐作品中加强和声力度、丰富和声色彩、表现和声手法、描绘音乐形象的一类重要的和声材料。

As a diatonic chord that the altered chords even do not belongs to the key,but it can not change the tonality ,its function is to strengthen the harmony tension,enrich the harmonic color,and describe the music figures.

变和弦作为不改变调性的非本调自然音的和弦，是音乐作品中加强和声力度、丰富和声色彩、表现和声手法、描绘音乐形象的一类重要的和声材料。

Since historical times,England ,where the early inhabitants were Celts, has been conquered three times .

从有历史以来，英国，在此地早期居住的是凯尔特人，已经被征服了三次。

Bluetooth OBEX File Transfer Enables the sending and receiving of files on your phone via Bluetooth.

蓝牙OBEX文件移动允许经过蓝牙传送和接受文件。。。。