查询词典 dosage

Our lab is mainly responsible for development,verification and transformation of analytical methods,tests of developed dosage forms, such as raw materials and excipients, packaging materials, various dosage items, and stability study.

主要负责分析方法的开发、验证及转移，负责研发制剂的检测，包括原辅材料、包装材料、各剂型项目检测、稳定性研究等。

OBJECTIVE To design and develop a clinical pharmacokinetics and individual drug dosage regimens system CPKDP program for estimating individual pharmacokinetic parameters and optimizing individualizing dosage regimens using routine clinical data of plasma levels. METHODS According to the principle of population pharmacokinetics and Bayes" formula, CPKDP program was written with FOXPRO 2.6 and BORLAND C++ 3.1, and was run on 486 microcomputer with UCDOS 5.0. RESULTS CPKDP program was adapted for drugs with different characteristics of pharmacokinetics, and for single dose or multiple dose administration. Using 1 or 2 measured drug concentrations, individual patient"s pharmacokinetic parameters were estimated based on population-average pharm-acokinetic parameters. CONCLUSION CPKDP program is applied for estimating pharmacokinetic parameters and optimizing drug therapy in individual patients.

目的为利用临床常规监测的血药浓度数据估算病人的个体药动学参数，优化给药方案，设计、研制了临床药动学给药个体化系统CPKDP程序方法依据群体药动学原理及Bayes公式，CPKDP程序用FOXPRO 2.6和BORLAND C++ 3.1开发，在希望汉字系统UCDOS 5.0平台上运行结果CPKDP程序适用于具有不同药动学特征的多种药物，适用于不同给药途径的单剂量或多剂量给药在群体药动学参数的基础上，结合病人个体特征，以1，2个血药浓度作为反馈，即可拟合估算个体药动学参数，优化给药方案结论经初步应用，CPKDP程序是应用Bayes反馈法开展临床个体化给药工作非常实用的工具

The influences of temperature, time, carboxylic acid dosage and catalyst dosage on the yield and optical purity were discussed.

着重研究了反应温度、反应时间、羧酸溶剂用量和催化剂的用量对产物收率和光学纯度的影响，获得了最佳工艺条件。

Methods The mice were given the meloxican tablet, ig, at the dosage of 0.56,1.13,2.25 and 9.00 mg.kg-1, then ip 0.8%acetic acid, and injecting the ear of mice. The meloxicans were given to rats, at the dosage of 1.5,3.0,6.0 mg.kg-1, to observe the effect of the meloxican inhibiting the paws swelling of rats by carrageen and granulation of rats by paper method.

观察美洛昔康对醋酸导致小鼠血管通透性增加和二甲苯引起小鼠耳肿胀抑制作用，以及角叉菜胶诱发大鼠足肿胀和纸片法引起大鼠肉芽增生的抑制作用。

Results The decoction intragastric injection showed a marked suppressive effect on the normal and adranalectomized rat's hind paw oedema induced by carrageenin. In addition, at the dosage of 150g/kg, Smilax china ig reduced the content of PGE2 in inflammatiory tissue and the content of NO, MDA in serum, and the content of NO in inflammatory tissue at the dosage of 90, 150g/kg.

结果：拔葜灌胃给药能明显抑制角叉菜胶所致正常大鼠和去肾上腺大鼠足肿胀，150g/kg拔葜可降低肿胀足爪组织中PGE2及血清中NO、MDA含量，90、150g/kg拔葜可降低肿胀足爪组织中NO含量。

Dosage is not to had been jumped over more more when using, must right amount, because cassia bark, clove, fennel, ginger and peppery wait makings, although they belong to natural dressing, but if dosage is excessive, the secondary action with be had particular likewise and even noxiousness and lure denaturation, when be being used so, answer with " peace is little not much " advisable.

使用时并非用量越多越好，一定要适量，因为桂皮。丁香。茴香。生姜以及胡椒等料，它们虽然属于天然调味品，但假如用量过度，同样具有一定的副作用乃至毒性和诱变性，所以使用时应以"宁少勿多"为宜。

Currently the dosage forms of the treating drug are ordinary oral tablet, suppository, clyster and so on.However, these dosage forms have shortages, such as used inconvenience, the efficacy is not ideal, relapse rate is high and number of adverse reactions is more.

目前其治疗药物主要是采用普通的口服片剂、栓剂、灌肠剂等剂型，但这些剂型存在使用不便、疗效不理想、复发率高和不良反应多等缺点。

The main component of ramie glial was pectin, hemicellulose and lignin; The single factor on degumming of ramie test was respectively analyzed with a high vigorous of pectinase KDN and TZ-888 compound enzyme （mainly xylanase and mannanase on the pH value, bath ratio, dosage of enzyme, metal ions, temperature and time.The orthogonal test of L9（34 were done by bath ratio, dosage of enzyme, temperature and time. The results showed that the best compages of KDN pectinase on degumming was 1∶12 of bath ratio,pH 8.6,1 mmol/L Mg2+,300 IU/g of KDN pectinase,35℃、6 h;the best compages of TZ-888 compound enzyme on degumming was 1∶18 of bath ratio,pH 4.0,1 mmol/L Ca2+, 500 IU/g of TZ-888 compound enzyme,45 ℃,6 h.

摘 要：本研究根据苎麻胶质的主要成分为果胶、半纤维素和木质素，用高活性的KDN果胶酶和TZ-888复合酶（主要是木聚糖酶和甘露聚糖酶）从pH值、浴比、酶用量、金属离子、温度、脱胶时间等方面进行单因素试验，然后选取影响显著的浴比、酶用量、温度，时间进行四因素三水平的脱胶试验，结果表明鲜麻采用KDN果胶酶脱胶最佳组合为浴比1：18，pH 8.6， 1 mmoL/L Mg2+，酶用量300 IU/g，温度35 ℃、时间6 h时处理，TZ-888复合酶脱胶最佳组为浴比1：12，pH 4.0， 1 mmoL/L Ca2+，酶用量500 IU/g，温度45 ℃，时间6 h进行脱胶为优化的试验条件。

The main component of ramie glial was pectin, hemicellulose and lignin; The single factor on degumming of ramie test was respectively analyzed with a high vigorous of pectinase KDN and TZ-888 compound enzyme （mainly xylanase and mannanase on the pH value, bath ratio, dosage of enzyme, metal ions, temperature and time.The orthogonal test of L9（34 were done by bath ratio, dosage of enzyme, temperature and time. The results showed that the best compages of KDN pectinase on dry ramie degumming was 1∶12 of bath ratio,pH 8.6,1 mmol/L Mg2+,20 IU/g of KDN pectinase,4℃、4h;the best compages of TZ-888 compound enzyme on degumming was 1∶18 of bath ratio,pH 4.0,1 mmol/L Ca2+, 300 IU/g of TZ-888 compound enzyme,40 ℃,5 h.

摘 要：本研究根据苎麻胶质的主要成分为果胶、半纤维素和木质素，用高活性的KDN果胶酶和TZ-888复合酶（主要是木聚糖酶和甘露聚糖酶）从pH值、浴比、酶用量、金属离子、温度、脱胶时间等方面进行单因素试验，然后选取影响显著的浴比、酶用量、温度，时间进行四因素三水平的脱胶试验，结果表明干苎麻采用KDN果胶酶脱胶最佳组合为浴比1：12，pH 8.6， 1 mmoL/L Mg2+，酶用量200 IU/g，温度45 ℃、时间4 h时处理，TZ-888复合酶脱胶最佳组为浴比1：18，pH 4.0， 1 mmoL/L Ca2+，酶用量300 IU/g，温度40 ℃，时间5h进行脱胶为优化的试验条件。

200 forepart pregnant women with ASA Ⅰ～Ⅱgrade who free will stop gestation,they were divided into 4 groups randomly :P group was simplicity propofol; F group, T group and K group was mainlined fentanyl 0.75μg/kg,tramadol 1mg/kg,ketamine0.2mg/kg respective before propofol abduction, and continuous detected MAP,HR,SpO2 in the operation, and to note first dosage and total dosage of propofol, revival time, leave hospital time, ill reactivity in the operation.

200例ASAⅠ～Ⅱ级、自愿终止妊娠的早孕妇女随机分为四组：P组，单纯异丙酚麻醉组；F组、T组、K组在异丙酚诱导前分别静注芬太尼0.75μg/kg、曲马多1mg/kg、氯胺酮0.2mg/kg。术中连续监测MAP、HR和 SpO2。记录各组病人异丙酚的首剂量和总剂量、苏醒时间、离院时间及术中术毕不良反应的发生情况。

Objective: To study the effect of polycythemia on blood oxygen saturation.

裴蕾目的：观察RBC剧增而引起的高粘血症对血氧饱和度的影响。

Based on SIMPLER algorithm in the curvilinear body-fitted coordinates, the calculations were performed for Pr=0.7, Re=10~1000 on non-orthogonal non-staggered grids which are generated by elliptic equation systems.

采用曲线坐标系下压力与速度耦合的SIMPLER算法，数值研究了周期性渐扩渐缩波纹通道内脉动流动与换热情况，流动Re数的范围为10~1000，Pr数为0.7。