查询词典 disastrous effect

order button is a consumer and the computer application carries out interactive simple and convenient method.the button control in object-oriented programming language visual basic is order button,order button is to be control in common use most in application,button control in visual basic is excessively simple,the event being not enough beautiful,hold out is few.be to realize colorful order button,making use of the image frame to load the beautiful photograph to simulate order button,the button effect,pushes down the effect striking the carriage return key or the escape key time button by the fact that event process realizes various peculiar "order button" effect,when button effect,mouse are labeled with shan strike when effect,the mouse bid streak including the button tacitly approving that.

摘 要：命令按钮是用户与计算机应用程序进行交互的最简便的方法。面向对象编程语言visual basic中的按钮控件就是命令按钮，命令按钮是应用程序中最为常用的控件，但是visual basic中的按钮控件过于简单，不够美观，支持的事件少。为实现多彩多姿命令按钮，可以利用图像框装载漂亮的图片模拟命令按钮，通过事件过程实现&命令按钮&的多种特殊效果，包括按钮的默认效果、鼠标划过时按钮的效果、鼠标单击时按钮的效果，按击回车键或逃逸键时按钮的效果。在实际编程中，设计好具有多种效果的按钮，是能否赢得用户的一件法宝。

This part Measures firms" size with market value of float shares, and divides each portfolio into quintiles and deciles to choose an appropriate grouping method. The second part divides the sample into two sub-samples to tests the different performance of "small firm effect" in two periods. The third part tests different performance of each month. The fourth part studies the "small firm effect" in five industries, the industry, the commerce, the public utilities, conglomerates and the properties, and uses Fame-Macbeth method to research "the small firm effect" in the different industries. The fifth part analyzes the reason why the "small firm effect" exists in China stock market referring to the western explanation about "the small firm effect and the character of China stock market. In the end, we provide some suggestion.

论文运用实证方法检验中国股市&小公司效应&的存在性，用流通股市值作为公司规模大小的度量，用五分组和十分组两种分组方法检验中国股市&小公司效应&的表现；把整个样本区间以2001年为界分为两个样本子区间，检验&小公司效应&在不同时间阶段的表现有何不同；分月检验&小公司效应&在不同月份的表现；把样本中所有上市公司按照行业分为五大类，工业类、商业类、公用事业类、房地产类和综合类，利用Fama-MacBeth法检验中国股市&小公司效应&在不同行业的表现；联系国外关于&小公司效应&存在原因的解释，结合中国股市的实际，分析中国股市&小公司效应&存在的原因，并提出了一些建议。

The effects and mechanism of GABAergic neurons, NOergic neurons, opioid peptide and cyclic adenosine monophosphate in the nucleus reticularis thalami on sleep-wakefulness cycle of rats and the effects and mechanism of the 5-HTergic nerve fibers project from the nucleus raphes dorsalis to RT on sleep-wakefulness cycle of rats were investigated with the methods of brain stereotaxic, nucleus spile, microinjection and polysomngraphy.1. The effects of GABAergic neurons in RT on sleep-wakefulness cycle of rats1.1 Microinjection of 3-mercaptopropionic acid (3-MP, a kind of glutamate decarboxylase inhibitor) into RT. On the day of microinjection, sleep only decreased a litter. On the second day, sleep marked decreased and wakefulness marked increased. On the third and fourth day, sleep and wakefulness stages resumed to normal.1.2 Microinjection of gamma-amino butyric acid (GABA 1.0μg) into RT enhanced sleep and reduced wakefulness compared with control; while microinjection of L-glutamate (L-Glu, 0.2μg) decreased sleep and increased wakefulness; microinjection of bicuculline (BIC, 1.0μg), a GABAA receptor antagonist, enhanced wakefulness and reduced sleep; microinjection of baclofen (BAC, 1.0μg), GABAB receptor agonist, had the same effects as GABA.2. The effects of NOergic neurons in RT on sleep-wakefulness cycle of rats2.1 Microinjection of L-arginine (L-Arg, 0.5μg) into RT decreased sleep compared with control, but there were on statistaical difference between L-Arg group and control; while microinjection of sodium nitroprusside (SNP, 0.2μg), a NO donor into RT, sleep marked decreased and wakefulness marked increased. Microinjection of nitric oxide synthase inhibitor, N-nitro-L-arginine (L-NNA, 2.0μg) into RT enhanced sleep and reduced wakefulness.2.2 After simultaneous microinjection of L-NNA (2.0μg) and SNP (0.2μg) into RT, SNP abolished the sleep-promoting effect of L-NNA compared with L-NNA group; after simultaneous microinjection of L-NNA (2.0μg) and L-Arg(0.5μg) into RT, we found that L-NNA could not blocked the wakefulness-promoting effect of L-Arg.3. The effects of opioid peptide in RT on sleep-wakefulness cycle of rats3.1 Microinjection of morphine sulfate (MOR, 1.0μg) into RT increased wakefulness and decreased sleep compared with control; while microinjection of naloxone hydrochloride (NAL, 1.0μg), the antagonist of opiate receptors, into RT, enhanced sleep and reduced wakefulness.3.2 After simultaneous microinjection of MOR (1.0μg) and NAL (1.0μg) into RT, the wakefulness-promoting effect of MOR and the sleep-promoting effect of NAL were not observed compared with control.4. The effects of cAMP in RT on sleep-wakefulness cycle of rats Microinjection of cAMP (1.0μg) into RT increased sleep and decreased wakefulness compared with control; microinjection of methylene blue (MB,1.0μg) into RT enhanced sleep and reduced wakefulness compared with control.5. The effects of the 5-HTergic nerve fibers project from DRN to RT on sleep-wakefulness cycle of rats5.1 When L-Glu (0.2μg) was microinjected into DRN and normal sodium (NS,1.0μg) was microinjected into bilateral RT. We found that sleep was decreased and wakefulness was increased compared with control; when L-Glu (0.2μg) was microinjected into DRN and methysergide (MS,1.0μg), a non-selective 5-HT antagonist, was microinjected into bilateral RT, We found that sleep was enhanced and wakefulness was reduced compared with L-Glu group.5.2 When p-chlorophenylalanine (PCPA, 10μg) was microinjected into DRN and NS (1.0μg) was microinjected into bilateral RT, We found that sleep was increased and wakefulness was decreased compared with control; microinjection of 5-hydroxytryptaphan (5-HTP, 1.0μg), which can convert to 5-HT by the enzyme tryptophane hydroxylase and enhance 5-HT into bilateral RT, could block the effect of microinjection of PCPA into DRN on sleep-wakefulness cycle.

本研究采用脑立体定位、核团插管、微量注射、多导睡眠描记等方法，研究丘脑网状核(nucleus reticularis thalami，RT)中γ-氨基丁酸(gamma-amino butyric acid ，GABA)能神经元、一氧化氮(nitrogen monoxidum，NO)能神经元、阿片肽类神经递质、环一磷酸腺苷(cyclic adenosine monophosphate，cAMP)及中缝背核(nucleus raphes dorsalis，DRN)至RT的5-羟色胺(5-hydroxytryptamine，5-HT)能神经纤维投射对大鼠睡眠-觉醒周期的影响及其作用机制。1 RT内GABA能神经元对大鼠睡眠-觉醒周期的影响1.1大鼠RT内微量注射GABA合成关键酶抑制剂3-巯基丙酸(3-MP，5μg)，注射当天睡眠时间略有减少，第二日睡眠时间显著减少，觉醒时间明显增多，第三、四日睡眠和觉醒时间逐渐恢复至正常。1.2大鼠RT内微量注射GABA受体激动剂GABA( 1.0μg)后，与生理盐水组比较，睡眠时间增加，觉醒时间减少；而RT内微量注射L-谷氨酸(glutamic acid， L-Glu， 0.2μg)后，睡眠时间减少，觉醒时间增加；RT内微量注射GABAA受体阻断剂荷包牡丹碱(bicuculline，BIC，1.0μg)后，睡眠时间减少，觉醒时间增加；RT内微量注射GABAB受体激动剂氯苯氨丁酸(baclofen，BAC，1.0μg)后，产生了与GABA相似的促睡眠效果。2 RT内NO能神经元对大鼠睡眠-觉醒周期的影响2.1大鼠RT内微量注射NO的前体L-精氨酸(L-Arg，0.5μg)后，与生理盐水组对比，睡眠时间略有减少，但无显著性意义；而RT内微量注射NO的供体硝普钠(Sodium Nitroprusside，SNP，0.2μg)后可明显增加觉醒时间，缩短睡眠时间；微量注射一氧化氮合酶抑制剂L-硝基精氨酸(L-arginine，L-NNA，2.0μg)后，引起睡眠时间增多，觉醒时间减少。2.2大鼠RT内同时微量注射L-NNA(2.0μg)和SNP(0.2μg)后与L-NNA组比较发现SNP逆转了L-NNA的促睡眠作用；RT内同时微量注射L-NNA(2.0μg)和L-Arg(0.5μg)后，与L-NNA(2.0μg)组比较发现L-Arg可以增加觉醒而缩短睡眠，其促觉醒作用未能被NOS的抑制剂L-NNA所逆转。3 RT内阿片肽对大鼠睡眠-觉醒周期的影响3.1大鼠RT内微量注射硫酸吗啡(morphine sulfate，MOR，1.0μg)后与生理盐水组对比，睡眠时间减少而觉醒时间增加； RT内微量注射阿片肽受体拮抗剂盐酸纳洛酮(naloxone hydrochloride，NAL，1.0μg)后与生理盐水组比较，睡眠时间增加而觉醒时间减少。3.2大鼠RT内同时微量注射MOR(1.0μg)和NAL(1.0μg)后，与生理盐水组对比，原有的MOR促觉醒效果和NAL的促睡眠效果都没有表现。4 RT内环一磷酸腺苷信使对大鼠睡眠-觉醒周期的影响大鼠RT内微量注射cAMP(1.0μg)后与NS(1.0μg)组比较，睡眠时间增多而觉醒时间减少；RT内微量注射亚甲蓝(methylene blue，MB，1.0μg)后，与NS组比较，睡眠时间增多而觉醒时间减少。5中缝背核投射到丘脑网状核的5-羟色胺能神经纤维对大鼠睡眠-觉醒周期的影响5.1大鼠DRN内微量注射L-Glu(0.2μg)，同时在双侧RT内微量注射NS (1.0μg)后，与对照组(DRN和双侧RT注射NS， 0.2μg)比较，睡眠时间减少，觉醒时间增多；大鼠DRN内微量注射L-Glu(0.2μg)，同时在双侧RT内微量注射二甲基麦角新碱(methysergide， MS， 1.0μg )后，与对照组(DRN注射L-Glu 0.2μg，双侧RT注射NS 1.0μg)比较，睡眠时间增多，觉醒时间减少。5.2大鼠DRN内微量注射对氯苯丙氨酸(p-chlorophenylalanine，PCPA，10μg)，同时在双侧RT内微量注射NS (1.0μg)后，与对照组(DRN和双侧RT注射NS， 1.0μg)比较，睡眠时间增多，觉醒时间减少；大鼠DRN内微量注射PCPA(10μg)，产生睡眠增多效应后，在双侧RT内微量注射5-羟色胺酸(5-hydroxytryptaphan ， 5-HTP， 1.0μg )后，与对照组(DRN注射PCPA 10μg，双侧RT注射NS 1.0μg)比较，睡眠时间减少，觉醒时间增多。

The result was a situation where all countries were eager to sell and reluctant to buy, and sought to achieve these mutually irreconcilable ends by setting up subsidies and bounties on exports, tariffs, and restrictions on imports, with disastrous results on world trade.

这样就进入到这样一个局面：所有国家都渴望卖，而不愿买，纷纷通过出口货物的补贴和奖励、关税、进口限制而达到相互间不可调和的目标；于是，世界贸易陷入灾难之中。

People says he is anile, he hate unceasingly; People should say he is little only tender, he with joy disastrous.

人们一说他衰老，他便恼恨不已；人们只要说他少嫩，他就高兴得不得了。

X., unless China becomes strong, either the collapse of Japan or her unquestioned ascendency in the Far East is almost certain to prove disastrous to China; and one or other of these is very likely to come about.

十，除非中国强大起来，不论是日本或她在远东不容置疑ascendency崩溃几乎肯定将是灾难性的中国和一个或几个其他很可能会发生。

During a period that should have been their happiest, Aylmer could only think of this disastrous subject.

在那段本来应该是他们最快乐的时光，艾尔默只能想到这个灾难性的主题。

At that momentary, we understood how bloodcurdling of the disastrous earthquake. Even after many years, I would be willies and run at immediately as soon as I listened the rumbling and felt the earth vibration.

直到那一刻，才知道了地震原来是这么的恐怖，以至多年以后只要一听到隆隆的响声和感觉到大地的颤抖，立刻就心惊肉跳，一种本能立刻就要跑。

Its light favored Blucher's ferocious pursuit, betrayed the traces of the fugitives, delivered up that disastrous mass to the eager Prussian cavalry, and aided the massacre.

月色给布吕歇尔的猛烈追击以许多方便，替他指出逃兵的动向，把那浩劫中的人流交付给贪戾的普鲁士骑兵，促成了那次屠杀。

I can't stress enough the disastrous consequences of a breach of contract.

我要强调，遵守合约是十分必要的。

We are forbidden from giving money to these shoeless, skinny children, as this will perpetuate begging.

向光着脚，骨瘦如柴的孩子施舍是不可以的，因为要招来无休无止的乞讨。

It would be hard not to fall victim to some sharpeyed policeman.

要想不被某个目光锐利的警察抓到，谈何容易。