查询词典 differentiation of a function

We review the effect of rare earth ions on bone metabolism as the following three aspects:(1) effect of rare earth ions on differentiation and function expression of osteoblasts and osteoclasts;(2) effect of rare earth ions on the osteogenic and adipogenic differentiation of bone marrow stromal cells;(3) effect of rare earth ions on bone mineral phase of animals.

本文回顾了稀土离子对骨代谢影响的研究进展，探讨了其药用和安全性问题，主要从以下三个方面进行综述：(1)稀土离子对成骨细胞和破骨细胞的分化和功能表达的影响；(2)稀土离子对骨髓基质细胞成骨分化和成脂分化的影响；(3)稀土离子对动物骨矿物相的影响。

We review the effect of rare earth ions on bone metabolism as the following three aspects:(1)effect of rare earth ions on differentiation and function expression of osteoblasts and osteoclasts;(2)effect of rare earth ions on the osteogenic and adipogenic differentiation of bone marrow stromal cells;(3)effect of rare earth ions on bone mineral phase of animals.

本文回顾了稀土离子对骨代谢影响的研究进展，探讨了其药用和安全性问题，主要从以下三个方面进行综述：(1)稀土离子对成骨细胞细胞和破骨细胞的分化和功能表达的影响；(2)稀土离子对骨髓基质细胞成骨分化和成脂分化的影响；(3)稀土离子对动物骨矿物相的影响。

In T cells,TGF-beta1 can inhibit their proliferation,inhibit the differentiation of Th1 and Th2,inhibit the differentiation of CTL,induce the generation of regulatory T cellsTregin B cells,TGF-beta1 can inhibit their proliferation,induce IgA class switch,it also can induce the apoptosis of immature and resting B cells;in NK cells,TGF-beta1 can inhibit the secretion of IFN-γand the cytolytic function of NK cells.

对T细胞，TGF-beta1可以抑制其增殖，抑制Th1和Th2细胞的分化，抑制CTL的分化，诱导调节性T细胞的产生；对B细胞，TGF-beta1可以抑制B细胞的增殖，诱导IgA的类别转换，还可以诱导不成熟和静息B细胞的凋亡。

In this thesis, we find that dlg is indispensible in the establishment of anterior-posterior and dorsal-ventral polarity of drosophila oocyte. Removal of Dlg function from the posterior follicle cells using the FLP/FRT system leads to disruption of oocyte skeleton reconstruction that is elicited by the failure of those posterior cells to differentiate normally in mid-oogenesis. We demonstrate that abnormity of Notch, JAK-STAT and EGFR signal pathway in dlg mutants contributes to this aberrant differentiation. dlg null mutant also blocks the normal differentiation of two groups of anterior follicle cell-stretched cell and centripetal cell, but not border cell, with a lower penetrance. However unlike the result in posterior follicle cells, Notch and JAK-STAT signaling are both undisrupted in all mutant anterior follicle cells, implying other fate determinants may be involved.

我们的研究发现，后端滤泡细胞中的Dlg在果蝇卵子发生中期卵母细胞前后轴和背腹轴建立过程中也是必须的，PFC中dlg完全缺失型突变引起PFC的分化异常，导致卵子发生中期卵母细胞骨架重组异常，Stau、Grk等极性决定蛋白定位错误。dlg突变阻碍了Notch、JAK-STAT、EGFR等调节PFC分化的信号通路的激活。dlg突变的PFC也没有获得前端滤泡细胞命运。dlg突变不影响前端滤泡细胞群中边界细胞的分化，但是在一定程度上影响伸展细胞和向心细胞的分化，并且这种影响不依赖于前端滤泡细胞Notch或JAK-STAT信号激活的异常。

Hes5 gene, a key downstream mediators of Notch signaling that functions by inhibiting the expression or activity of positively acting bHLH factors, is a member of bHLH transcription factor family which acts as a positive-negative transcriptional regulators which is expressed transiently in different stages in cells growth and differentiation and orchestrate those precisely timed and progressive maturational events underlying cell fate decisions according to orders of time and spatial and coordinated the function of majority of signaling transduction on target genes to influence the proliferation and differentiation.

Hes5是Notch通路转导途径的一个关键的下游信号分子，通过抑制正调控bHLH因子的表达和活性来发挥作用，隶属于碱性螺旋-环区-螺旋转录因子家族。该家族形成一个正负转录调节器，按时空顺序短暂表达于细胞发育分化的不同阶段，介导和协调多种信号系统对大量靶基因的作用，影响细胞增殖、分化。

The function of terminal differentiation is to produce specific tissue cell-keratinocyte whose function is to protect the tissue, while the function of apoptosis is to delete the specific cells to keep homeostasis of the tissue.

终末分化的结果是产生特定的组织细胞-角质细胞，以保护上皮组织；细胞凋亡则是选择清除特定的细胞，以保持组织的平衡稳定。

With the discussion of extreme value problem of the multiple-valued function,and the popularizing of extreme value theory of the two-value function,This paper obtains differentiation rule about the extreme value of the multiple-value function,and illustrates the apllication of the theory with the example,providing proper guidance for the teaching of calculus.

文章讨论了多元函数的极值问题，并将二元函数的极值判定定理加以推广，得到关于多元函数极值的判定法则，并举例说明其应用，这对微积分的教学有一定的指导意义。

Study shows that strengthening body resistance and archaeus herbs have many effects,such as improving and adjusting immunity function,protecting bone marrow,improving haematogenesis function,raising digest and absorb function,improving substance metabolism,preventing gene mutation,inhibiting tumor cell proliferation,inducing tumor cell differentiation or apoptosis,resisting tumor invasion and metastasis,inhibiting formation of tumor vessel and activity of telomerase,etc.It's possibly the result of synergistic effect by multi-pathway and multi-target.

研究表明，扶正培本药物具有增强和调节机体免疫功能、保护骨髓及提高机体造血机能、增加消化吸收功能，改善物质代谢、阻止基因突变、抑制肿瘤细胞增殖、诱导分化、促使肿瘤细胞凋亡、抗肿瘤侵袭与转移、抑制肿瘤血管形成及肿瘤细胞端粒酶活性等多种作用，其发挥的扶正作用可能是多途径、多靶点联合协同作用的结果。

For the Riemann boundary value problems for the first order elliptic systems , we translates them to equivalent singular integral equations and proves the existence of the solution to the discussed problems under some assumptions by means of generalized analytic function theory , singular integral equation theory , contract principle or generaliezed contract principle ; For the Riemann-Hilbert boundary value problems for the first order elliptic systems , we proves the problems solvable under some assumptions by means of generalized analytic function theory , Cauchy integral formula , function theoretic approaches and fixed point theorem ; the boundary element method for the Riemann-Hilbert boundary value problems for the generalized analytic function , we obtains the boundary integral equations by means of the generalized Cauchy integral formula of the generalized analytic function , introducing Cauchy principal value integration , dispersing the boundary of the area , and we obtains the solution to the problems using the boundary conditions .

对于一阶椭圆型方程组的Riemann边值问题，是通过把它们转化为与原问题等价的奇异积分方程，利用广义解析函数理论、奇异积分方程理论、压缩原理或广义压缩原理，证明在某些假设条件下所讨论问题的解的存在性；对于一阶椭圆型方程组的Riemann-Hilbert边值问题，利用广义解析函数理论、Cauchy积分公式、函数论方法和不动点原理，证明在某些假设条件下所讨论问题的可解性；广义解析函数的Riemann-Hilbert边值问题的边界元方法是利用广义解析函数的广义Cauchy积分公式，引入Cauchy主值积分，通过对区域边界的离散化，得到边界积分方程，再利用边界条件得到问题的解。

We prove the equivalent conditions of completely monotone function, we also discuss the relationship of positive definite function, semi-positive definite function and completely monotone function when the function take values in a commutitive von Neumann algebras.

我们证明了完全单调函数的几个等价条件，并且讨论了取值于交换von Neumann代数的正定函数，半正定函数及完全单调函数之间的关系。

For the head-teacher of the class said that I had seriously broken the school rules,which led me to a three-day suspend class.

为什么呢？因为我的班主任说我严重的违反了校规，于是让我停课三天。

Many of them believe that the conversion of thousands of working-class folk in England spared that nation from the mass carnage and the tyranny that came with the revolution in France.

他们之中有许多人相信，在英国数以千计的劳工阶级之悔改信主使英国免於遭受如法国大革命所造成的大屠杀和专制暴政。