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Genes were found to be differentially expressed in EOM compared to Quadriceps femoris limb muscle, using a twofold cutoff.

目前不清楚为何眼外肌在不同疾病中受累情况不同，有人认为可能与同种异型基因表达有关。

Based on the prior information obtained by qualitative inversion, the two stages inversion method was put forward. That is, the first stage is that distinguishing the high-quality element and non- high-quality element, and determining the initial iteration value of element sound velocity reasonably. The second stage is that treating differentially the constraint weights of the high-quality element and non- high-quality element, and then quantitatively inversing the final sound velocity distribution. The results of two concrete specimens indicate that the two stages inversion method can inhibit artifacts effectively and has better defect identification effect than normal one stage inversion.

在获取定性反演先验信息的基础上，提出了两阶段反演的方法：第一阶段，区分优质像元和非优质像元，合理确定像元声速的迭代初值；第二阶段，区别对待优质像元和非优质像元的约束权重，定量反演最终的速度分布。2个混凝土试件的模型试验表明，两阶段反演能有效抑制伪像，具有比常规的一阶段反演更好的缺陷识别效果。

RESULTS: Image analysis of two-dimensional map revealed 72 differentially expressed proteins between MHCC97-H and MHCC97-L cells, and 9 protein peaks (including M2 pyruvate kinase,α-subunit of ATP synthase, heat shock protein 60, Toll-like receptor 9, flavoprotein oxygenase, pro-calreticulin, manganese superoxide dismutase, nm23-H1, and G-protein-coupled receptor kinase 5) were further identified by tryptic digestion, peptide mass fingerprinting and mass spectrometry.

结果： 2D图谱显示共有72个差异蛋白条带，共鉴定出了9个差异蛋白，分别为M2型丙酮酸激酶、ATP合成酶α亚单位、热休克蛋白60、Toll样受体9、含黄素单加氧酶、钙网硬蛋白前体、锰超氧化物岐化酶、nm23-H1、G-蛋白偶连受体激酶5；其中4个蛋白在高转移细胞株MHCC97-H中表达升高， 5个蛋白在低转移细胞株MHCC97-L表达升高。

By contrast, negative memories differentially increased neural activity in the right middle temporal gyrus only.

相比之下，负向记忆的情况不同，它只在右侧颞中回表现出增加的神经活动。

Using gene chips to screen an SSH library could efficiently identify those differentially expressed genes without the need to examine previously cloned genes, and increase the number of target genes by decreasing the examination of multiple'house-keeping'genes.

因此，基于SSH方法和基因芯片技术的特点，将两者联合应用将是有针对性地发现大量差异表达基因的有效方法，而且可以大大提高发现新基因的机率。

In a holistic and systematic view, we discussed the progress mechanism of acute leukemia, found a hypothetic pathway of meningioma progression, and described the network interaction of a set of genes which differentially expressed between androgen independent prostate cancer and androgen dependent prostate cancer significantly and related to hormones.

从系统和整体的角度，对急性白血病的发生发展机制进行了探讨，构建了一条脑膜瘤发生发展的通路，对在前列腺癌中差异表达，且和激素相关的基因的网络相互作用进行了阐述。

Finally, We searched for paralogous genes appeared in the contrary differentially pathways of normal and disease status, respectively. It is very likely to find an intersectional gene between different pathways, because this intersectional gene has higher probability to associate with both these paralogous genes in different situation.

最后搜寻疾病和正常的路径之间的paralogous基因，也许可能会在两组之间找到相同的基因，而这相同的基因可能和paralogous基因有关。

Two gene fragments of DEN-1(GenBank accession number DQ886390)and DEN-2(GenBank accession number DQ886391),differentially expressed between the ocular skin tissues of normal and albino turbot,were isolated by mRNA differential display and sequenced.It was confirmed by RT-PCR method that the expression levels of both DEN-1 and DEN-2 were down-regulated in the ocular skin tissue of albino turbot.The sequence homology search of DEN-1 revealed high sequence homologies with the UGGT genes of zebrafish and cattle,and the Ugcgl1 gene of Norway rat.High sequence homologies of DEN-2 were observed with the eya4 gene(the eye absent homolog 4)from red jungle fowl,zebrafish,human,Norway rat,mouse and dog.

应用mRNA差异显示技术，对比研究正常与白化大菱鲆有眼侧皮肤组织，克隆差异表达基因，经测序，RT-PCR 验证，差异表达基因片段DEN-1(GenBank登录号：DQ886390)与DEN-2(GenBank登录号：DQ886391)均在白化大菱鲆有眼侧皮肤组织中下调表达；通过BLAST检索发现，DEN-1与GenBank中的斑马鱼和牛的类似尿苷二磷酸-葡萄糖：糖蛋白葡糖基转移酶基因、与挪威鼠类似尿苷二磷酸-葡萄糖：神经酰氨葡糖基转移酶1(Ugcgl1)基因有较高同源性；DEN-2 与原鸡、斑马鱼、人、挪威鼠、家鼠和狗的眼缺乏同源框4(eya4)基因的同源性均较高。

The comparative transcript profiles between OP and OR rats reveal some differentially expressed genes involved in lipids metabolism, ketone body production, blood pressure regulation and adipoctyes differentiation processes.The combined strategy of metabonomics and transcriptomics provides comprehensive information of metabolic characters of obesity and corresponding mechanisms to obese-related metabolic disorders from a systematic view, e.g.

高脂饮食喂养建立的OP大鼠体内的整体代谢特征与OR大鼠不同，具体包括：交感神经系统活性、能量代谢、脂肪酸代谢、氨基酸代谢以及肠道菌群结构等；OP和OR两种表型的转录组学比较也揭示了部分参与脂质代谢、酮体生成、血压调节和脂肪细胞分化等调控过程的基因存在差异性表达。

Based on the Maximum Likelihood receiver principle,Coherent-Noncoherent integration is analyzed. It has serious square loss Characterization, especially in real data. Differentially coherent integration algorithm which is frequently used in spread spectrum communication is analyzed in detail for high sensitivity signal detection.

基于最大似然接收机原理，详细分析了相干-非相干(Coherent-Noncoherent)积分算法，表征出该算法在高灵敏度条件下由于非相干次数增加带来的平方衰减，实测数据的分析证实了这个问题更为严重。

The statistical analysis of this large set of mutations has led us to propose a diagnostic strategy that should help with the molecular work-up of optic neuropathies.

这一大系列基因突变的统计学分析引导我们提出一个诊断策略，可以帮助我们对视神经病变进行分子学的诊断检查。

The results show that the pipe grouting changes the mechanical parameters of surrounding rocks to achieve the security of engineering objectives by reinforcing surrounding rocks and bolcking the water.

研究表明：小导管注浆一方面改变了围岩的力学参数，另一方面利用浆液的固结特性可以实现堵水和加固围岩的工程目标，使隧道在开挖过程中的安全得到保障。