查询词典 curative effect

The stable clones are further identified by RT-PCR and Western blot; 6 MTT assay is used to investigate the effect of ZNRD1 on the cell growth of cells (AGS, SGC7901, MKN28, NIH3T3, GES-1); 7 Soft agar assay is used to investigate the effect of ZNRD1 on the clonality of cells (AGS, MKN28); 8 Nude mice assay is used to investigate the effect of ZNRD1 on the cell growth of gastric cancer cells (AGS, MKN28); 9 Flow cytometry is used to investigate the effect of ZNRD1 on the cell cycle distribution of cells (AGS, MKN28, NIH3T3, GES-1); 10 Flow cytometry is used to investigate the effect of ZNRD1 on the cell apoptosis of cells (AGS, MKN28, NIH3T3); 11 MTT assay is used to investigate the effect of ZNRD1 on the drug sensitivity of cancer cells (SGC7901, SGC7901/VCR, HL-60, HL-60/VCR) in vitro; 12 SRCA is used to investigate the effect of ZNRD1 on the drug sensitivity of gastric cancer cells (SGC7901, SGC7901/VCR) in vivo; 13 Flow cytometry is used to investigate the effect of ZNRD1 on adriamycin accumulation of cancer cells (SGC7901, SGC7901/VCR, HL-60, HL-60/VCR); 14 Transmission electron microscope is used to investigate the effect of ZNRD1 on the sensitivity of SGC7901 cells towards drug-induced apoptosis; 15 Flow cytometry and DNA ladder assay are used to investigate the effect of ZNRD1 on the sensitivity of cells (SGC7901, SGC7901/VCR, HL-60/VCR) towards drug-induced apoptosis; 16 Microarray is used to investigate the profiling of ZNRD1-responsive genes in gastric cancer cells (AGS, MKN28, SGC7901, SGC7901/VCR); 17 RT-PCR and Western blot are used to identify the results of microarray; 18 Reporter gene assay is used to investigate the effect of ZNRD1 on the transcriptional activity of cyclin D1; 19 Reporter gene assay is used to investigate the effect of ZNRD1 on the transcriptional activity of MDR1; 20 Kinase assay is used to investigate the effect of ZNRD1 on the activity of cyclin E-CDK2 kinase; 21 The antisensenucleic acids of p21 is used to inhibit the expression of p21, and flow cytometry is used to investigate the effect of p21 on ZNRD1-induced cell cycle arrest in gastric cancer cells; 22 The antisensenucleic acids of p27 is used to inhibit the expression of p27, and flow cytometry is used to investigate the effect of p27 on ZNRD1-induced cell cycle arrest in gastric cancer cells; 23 Liposome is used to up-regulate the expression of Skp2, and flow cytometry is used to investigate the effect of Skp2 on ZNRD1-induced cell cycle arrest in gastric cancer cells; 24 Western blot is used to investigate the effect of ZNRD1 on the stability of Skp2 and p27 in gastric cancer cells; 25 MVD assay is used to investigate the effect of ZNRD1 on the angiopoietic activity of gastric cancer cells; 26 ELISA is used to investigate the effect of ZNRD1 on the expression of VEGF165 in gastric cancer cells; 27 The roles of DARPP-32 in MDR of gastric cancer cells are investigated using gene transfection, MTT assay, SRCA, flow cytometry and DNA ladder assay.

应用杂交瘤技术制备ZNRD1的首个单克隆抗体；2）利用RT-PCR、Western blot和免疫组化检测ZNRD1在胃癌组织、胃炎组织、正常胃上皮组织、胃癌细胞和正常胃组织上皮细胞中的表达；3）构建ZNRD1的小干扰RNA载体，并测序鉴定；4）利用脂质体将ZNRD1的真核表达载体及其空载体转染胃癌细胞（AGS、SGC7901、MKN28）和小鼠成纤维细胞（NIH3T3），G418筛选后进行鉴定；5）利用脂质体将ZNRD1的小干扰RNA载体及其空载体转染药敏胃癌细胞（SGC7901）、正常胃组织上皮细胞（GES-1）、对长春新碱耐药的胃癌细胞（SGC7901/VCR）、药敏白血病细胞（HL-60）、对长春新碱耐药的白血病细胞（HL-60/VCR），G418筛选后进行鉴定；6）利用MTT实验检测ZNRD1高/低表达对细胞（AGS、SGC7901、MKN28、NIH3T3、GES-1）生长的影响；7）通过软琼脂克隆形成实验检测上调ZNRD1对AGS、MKN28细胞克隆形成能力的影响；8）通过裸鼠成瘤实验检测上调ZNRD1对AGS、MKN28细胞体内成瘤性的影响；9）通过流式细胞仪分析ZNRD1高/低表达对细胞（AGS、MKN28、NIH3T3、GES-1）的细胞周期的影响；10）通过流式细胞仪分析上调ZNRD1对细胞（AGS、MKN28、NIH3T3）的凋亡的影响；11）通过MTT实验检测ZNRD1高/低表达对细胞（SGC7901、SGC7901/VCR、HL-60、HL-60/VCR）体外药物敏感性的影响；12）通过肾包膜下移植法检测ZNRD1高/低表达对细胞（SGC7901、SGC7901/VCR）体内药物敏感性的影响；13）通过流式细胞仪分析ZNRD1高/低表达对细胞（SGC7901、SGC7901/VCR、HL-60、HL-60/VCR）内阿霉素蓄积和泵出的影响；14）通过透射电镜检测上调ZNRD1对SGC7901细胞凋亡敏感性的影响；15）通过流式细胞仪和DNA梯度试验检测ZNRD1高/低表达对细胞（SGC7901、SGC7901/VCR、HL-60）凋亡敏感性的影响；16）通过基因芯片检测ZNRD1高/低表达对胃癌细胞内基因表达谱的影响；17）利用RT-PCR、Western blot对基因芯片的结果进行鉴定；18）利用报告基因实验检测ZNRD1对cyclin D1的启动子活性的调节作用；19）利用报告基因实验检测ZNRD1高/低表达对MDR1的启动子活性的调节作用；20）利用激酶试验检测ZNRD1对cyclin E-CDK2 激酶活力的影响；21）利用反义核酸技术抑制p21的表达；通过流式细胞仪检测抑制p21对ZNRD1介导的细胞周期阻滞的影响；22）利用反义核酸技术抑制p27的表达；通过流式细胞仪检测抑制p27对ZNRD1介导的细胞周期阻滞的影响；23）利用脂质体转染法上调Skp2的表达；通过流式细胞仪检测上调Skp2对ZNRD1介导的细胞周期阻滞的影响；24）利用Western blot检测ZNRD1对p27和Skp2的蛋白稳定性的影响；25）利用微血管密度实验检测ZNRD1对AGS、MKN28细胞裸鼠移植瘤微血管形成的影响；26）利用ELISA检测ZNRD1对AGS、MKN28细胞培养上清和移植瘤匀浆中VEGF165含量的影响；27）利用脂质体转染法、MTT实验、肾包膜下移植法、流式细胞仪和DNA梯度试验检测新耐药相关分子DARPP-32对细胞（SGC7901、SGC7901/VCR、对阿霉素耐药的胃癌细胞SGC7901/ADR）多药耐药表型的影响；利用脂质体转染法和MTT实验检测下调ZNRD1对DARPP-32介导的胃癌多药耐药的调控作用。

Attar, which is called "golden liquid" in domestic and overseas market, has sweet aroma of rose, The product has multiple curative effect including psychological curative effect: preventing hypochondria, alleviate nervous, chirk up; body curative effect: helping systemic circulation, shrinking blood capillary, preventing veinlet burst, diminishing inflammation to cholecystitis, conjunctivitis, ophthalmia.

玫瑰油——在国内外市场上素有"液体黄金"之称，具有甜的玫瑰花香气。心灵疗效：具有抗忧郁、神经紧张，提振精神，使人兴奋等。身体疗效：协助体循环，能收缩微血管，所以是小静脉破裂的神奇之宝。对胆囊炎、结膜炎、眼炎有消炎作用，能刺激胆汁分泌，清血、利脾、健胃、补身、止呕吐。

Attar, which is called "golden liquid" in domestic and overseas market, has sweet aroma of rose, The product has multiple curative effect including psychological curative effect: preventing hypochondria, alleviate nervous, chirk up; body curative effect: helping systemic circulation, shrinking blood capillary, preventing veinlet burst, diminishing inflammation to cholecystitis, conjunctivitis, ophthalmia.

玫瑰油——在国内外市场上素有&液体黄金&之称，具有甜的玫瑰花香气。心灵疗效：具有抗忧郁、神经紧张，提振精神，使人兴奋等。身体疗效：协助体循环，能收缩微血管，所以是小静脉破裂的神奇之宝。对胆囊炎、结膜炎、眼炎有消炎作用，能刺激胆汁分泌，清血、利脾、健胃、补身、止呕吐。

This may be explained by follows: First, Decoction Shenkangling can regulate the homeostasis of NEI network and reduce the increased activity of NF-κB to restrain the action of inflammatory-sclerotic media; Second, it can redress the disequilibrium of the ratio of TXA2/PGI2 to reform the hypercoagulable state; Third, it can enhance albumin and reduce cholesterol and triglyceride; Fourth, it can amend the renal damage and protect the function of renal tubule and stroma to prevent the transformation from MCD to FSGS; Last, it can lessen urine protein in AN rats markedly and relieve the side effects of prednisone.4. NF-κB, TXA2 and PGI2, along with the renal pathomorphology and so on can all be the indexes of the diagnosis of Symptom of "Kidney Deficiency and Blood Stasis" and the application of Methods of "Benefiting the kidney and Promoting blood circulation" in TCM.5. The curative effects on AN rats by treatment of integrating Traditional Chinese Medicine with prednisone are much better than using prednisone only. And the curative effects on AN rats by treatment of matching Decoction Shenkangling, having the function of "Benefiting the kidney and Promoting blood circulation", with Prednisone are much better than using Prednisone only.6. When it referred to decreasing urine protein, cholesterol and triglyceride and increasing albumin, Decoction Zhibodihuang excesses Decoction Taohongsiwu. However, when it referred to regulating the disequilibrium of TXA2/PGI2 and meliorating renal lesion, Decoction Taohongsiwu exceeds Decoction Zhibodihuang.7. The curative effects on AN rats by treatment of matching Methods of "Benefiting the kidney and Promoting blood circulation" with Prednisone overmatches using Prednisone matching Method of "Benefiting the kidney" or Method of " Promoting blood circulation" only.

益肾活血中药肾康灵能显著改善AN鼠的肾虚血瘀证的临床表现和实验指标，这可能与中药肾康灵能调理AN鼠机体的NEI网络功能稳态，降低异常升高的NF-κB活性，抑制免疫炎症/硬化介质环节，纠正失衡的TXA2/PGI2，改善AN鼠血液高凝状态，提高AN鼠的血清Alb，降低Ch和TG，减轻AN鼠的肾脏组织病理学变化，保护肾小管－间质功能，阻止MCD向FSGS转化；显著减轻AN鼠的尿蛋白水平以及减轻激素副作用有关。4、NF-κB、 TXB2和6-keto-PGF1α以及肾脏病理形态学改变等，都可作为中医肾虚血瘀证诊断和益肾活血法应用的客观指标。5、中西医结合干预AN鼠疗效优于单纯激素治疗；强的松配合益肾活血中药肾康灵组的综合疗效显著优于单纯强的松组。6、知柏地黄汤组在降低尿蛋白、提高血清Alb、降低Ch和TG疗效上优于桃红四物汤组；桃红四物汤组在纠正失衡的TXA2/PGI2和减轻肾脏病理损害方面优于知柏地黄汤组。7、激素配合益肾活血法干预AN鼠在一定程度上优于激素配合益肾法或活血法。

Appraised the clinical effect of the flavone of rhizome drynania on Senile Osteoporosis, according to the dynamic observation on integrative scores of lumbodorsal pain and lumbodynia,"VAS section grading method" on lumbodynia,"Barthel index rating method" on ADL, detected BMD on anterior-posterior position lumbar2~4 vertebra body and proximate of femur including neck/ward/troch, and determined the index of bone transition including BGP/PINP/ICTP through the radioimmunity method before and after treated half a year, then contrast intragroup and selfgroup. Depending on the standard of curative effect, contrast the difference of curative effect between two groups.

采用随机对照的方法，分为治疗组36例，对照组34例，依据对腰背痛及腰痛综合评分进行动态观察；依据"疼痛VAS线段分级法"对腰背痛（静止痛、翻身痛、久坐痛、起身痛、弯腰痛、步行痛、睡眠痛、叩击痛、压痛）进行量化动态观察；依据"Barthel指数评定法"对老年性骨质疏松症日常生活活动能力进行观察；采用双能X线骨密度仪对腰椎(L2-L4)、股骨近端各部位：股骨颈、股骨三角区、股骨粗隆进行骨密度定量检测；应用放射免疫法对骨转换指标进行测定，骨形成指标：骨钙素、Ⅰ型前胶原氨基端前肽；骨吸收指标：Ⅰ型胶原交联羧基末端肽等，评价骨碎补总黄酮治疗老年性骨质疏松症的临床效果。

Ningnaotang have curative effects on cerebral edema at the Acute hemorrhagic Apoplexy Stage.So the dosis and the side effect of mannit were decreased. Ningnaotang has an effect on the content changes of CRP and FIB, the state of illness of the patients with acute cerebral hemorrhage. This investigation show Ningnaotang is helpful to the prognosis and curative effect for patients with acute cerebral hemorrhage

宁脑汤对急性出血性中风患者的脑水肿有减轻作用，可以减少甘露醇的用量，从而降低了甘露醇的副作用，并且对血浆纤维蛋白原和C-反应蛋白含量变化及病情有影响，故使用宁脑汤有助于改善急性出血性中风患者的预后和疗效。

objective observing the clinic effect that curing menopause syndrome with wuzangyangyin soup that self-designed.methods the 120 menopause syndrome patients have divided into two groups randomly,these patints who accorded with the diagnosing standard of the traditional chinese medicine,the cured group giving the self-desingedwuzangyangyin soup,the contrasted group giving "genian an",course of treatment is 1 months.observing the change conditions of effects before cure and after with the two groups,the change conditions include curative effects、symptom score、fsh、e2.results the curative ratio:the cured group having for 10%,the contrasted group being 2.5%.the effective rato:the cured guoup having for 93.7%,the contrasted group being82.5%,with comparing the effect between the two group, the difference is obvious,p.05.conclusion the self-designed"wuzangyangyin soup"has an effect to cure menopause syndrome.

目的 观察五脏养阴汤治疗更年期综合征的临床疗效。方法将符合中医诊断标准的120例更年期综合征患者随机分为两组，治疗组给予自拟五脏养阴汤（由黄精、麦冬、白芍、生地、玉竹、五味子、花粉、丹皮等药物组成），对照组给予更年安治疗，疗程1个月。观察治疗前后两组疗效、症状积分及fsh、e2变化情况。结果治愈率治疗组10.0％，对照组2.5％；总有效率治疗组93.7％，对照组82.5％。两组治愈率及总有效率比较，差异均有显著性（p＜0.05）。结论自拟五脏养阴汤治疗更年期综合征有较好的疗效。

Appraised the clinical effect of the flavone of rhizome drynania on Senile Osteoporosis, according to the dynamic observation on integrative scores of lumbodorsal pain and lumbodynia,"VAS section grading method" on lumbodynia,"Barthel index rating method" on ADL, detected BMD on anterior-posterior position lumbar2~4 vertebra body and proximate of femur including neck/ward/troch, and determined the index of bone transition including BGP/PINP/ICTP through the radioimmunity method before and after treated half a year, then contrast intragroup and selfgroup. Depending on the standard of curative effect, contrast the difference of curative effect between two groups.

采用随机对照的方法，分为治疗组36例，对照组34例，依据对腰背痛及腰痛综合评分进行动态观察；依据&疼痛VAS线段分级法&对腰背痛（静止痛、翻身痛、久坐痛、起身痛、弯腰痛、步行痛、睡眠痛、叩击痛、压痛）进行量化动态观察；依据&Barthel指数评定法&对老年性骨质疏松症日常生活活动能力进行观察；采用双能X线骨密度仪对腰椎(L2-L4)、股骨近端各部位：股骨颈、股骨三角区、股骨粗隆进行骨密度定量检测；应用放射免疫法对骨转换指标进行测定，骨形成指标：骨钙素、Ⅰ型前胶原氨基端前肽；骨吸收指标：Ⅰ型胶原交联羧基末端肽等，评价骨碎补总黄酮治疗老年性骨质疏松症的临床效果。

The effect of treatment is negatively correlated with the course of disease, generally, the effect is much worse with the course of disease is much longer; The effect is positively correlated with the course of treatment, it is better if the course of treatment is longer.The group of more than one year is much excellent than the group of less one year. The ex-electroencephalogram before treatment is normal, on edge and a little abnormal, the effect is better. As regards CT or MR result, there is difference between the effective group and the ineffective group. The result of CT and MR is negative, the effect is better, and the effect to demyelination and leukoencephalopathy is most worst.However,for the tipe of much abnormality, the effect is the most worst.The effect is related to course of disease.The effect is better if the course is shorter.There is no difference in the tipe of disease the symptoms before episode, the frequency of episode, the inducing reasons, the age, sex and so on.

病程的长短与疗效存在负相关关系，病程越长疗效越差；疗程与疗效存在正相关关系，疗程越长疗效越好；疗前脑电图的异常程度与疗效存在负相关关系，正常、边缘及轻度异常者，疗效较好，重度异常者疗效最差；无效组与有效组在CT及MR检查结果上有差异，有阴性者疗效好，阳性者疗效差，脱髓鞘及脑白质病疗效最差的趋势；疗效与性别无相关性；无效组与有效组在发作类型、既往病史、辨证分型、发作先兆、疗前发作频率、诱因、发病年龄、就诊前所用药物方面无差异。

As a whole, this article investigates the investment effect problem from a new view of regional economics. It covers the economic, social and ecological effect of regional investment; it defines the concepts of investment effect and regional investment effect, deciphers the connotation, classification and influential factors of investment effect, and establishes a basic theory framework of investment effect research; constructs a fire-new regional investment effect evaluation model that could evaluate comprehensively the economic, social and ecological effect of regional investment, including evaluation index system and evaluation method, which supplies the gap of regional investment effect evaluation in academic community.

总体上看，本文从区域经济学这一新的视角研究投资效应问题，内容涵盖了区域投资的经济效应、社会效应和生态环境效应；界定了投资效应、区域投资效应的概念，解读投资效应的内涵、分类与影响因素，建立了投资效应研究的基本理论框架；构建一个对区域投资的经济效应、社会效应和生态环境效应进行综合评价，包括评价指标体系和评价方法在内的全新的区域投资效应评价模型，弥补了学术界在区域投资效应评价方面的空白。

So it was last week in Selma , alabama.

上星期在亚拉巴马州塞尔马市发生的事件也是这样一个转折点。

The group also spearheads various social programs in China.

该组织还带头参与中国的各种社会活动。