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The cytotoxicity of these compounds were valuated by MTT and SRB methods using three cancer cell lines: HL-60, A-549, P-388. Cyclo-shikonin, and cyclo-alkannin have high cytotoxicity against HL-60.The chiral center of side chain has no effect on their activity. 2- 1-(Acetyloxy-4-methyl-3-pentenyl -5, 8-dihydroxy-1, 4-naphthoquinone (105) has strong inhibition effect on P-388 cells. 2- 1-(isooctyloxy-4-methyl-3-pentenyl -5, 8-dihydroxy-1, 4-naphthoquinone (108) and 2- 1-(2-furoyloxy-4-methyl-3-pentenyl -5, 8-dihydroxy-1, 4-naphthoquinone (112) have high inhibition on A-549.Shikonin (1), alkannin (2), and their derivatives have the structural features of a planar chromophores and short side chain. We examined the ability to inhibit the telomerase.

抗肿瘤活性初步筛选测试采用小鼠白血病P-388肿瘤细胞和人肺癌A-549肿瘤细胞进行，结果表明侧链羟基的手性对抗肿瘤活性无明显影响；有数个化合物具有很好的体外抑制活性，特别是化合物2-（1-异辛酰氧基-4-甲基-3-戊烯基）-5，8-二羟基-1，4-萘醌（108）和2-[1-（2-呋喃甲酰氧基）-4-甲基-3-戊烯基]-5，8-二羟基-1，4-萘醌（112）体外显示对人肺癌A-549肿瘤细胞有强效；2-（1-乙酰氧基-4-甲基-3-戊烯基）-5，8-二羟基-1，4-萘醌（105）对小鼠白血病P-388肿瘤细胞有强效；环紫草素和环异紫草素对人白血病HL-60细胞有强烈抑制作用。

Global Supply Chain ; Value Chain Specialization ; Import and Export Trade ; Allocation of Profits

全球供应链；价值链分工；进出口贸易；利益分配

An alterative chain, the second chain, bypasses the wholesaler, resulting in a lower purchase price for the consumer.

一个改变的链条，第二链，绕过批发商，在为消费者带来更低的价格购买。

Modification of the side chain radical of β-lactam class antibiotic is a possible effective way,while the mother nuclide maintain the activity, but the different side chain radical alternating the drug tolerance of bacterium.

改造β-内酰胺类抗生素的侧链，不同侧链改变了细菌的耐药性，而其母核仍保持抗菌活性，这可能是克服抗生素使用剂量不断增大的一条有效途径。

In the proof an analytic technique for the study of strong limit theorems of Markov chain is extended to the case of Even odd Markov chain fields on trees.

证明中将研究马氏链强极限定理的一种新的分析方法推广到树上奇偶马氏链场的情形。

At present domestic retail business has formed the much configuration such as large country chain and regional chain to interlink mode, its huge matter flows deserve to sent the current situation to be destined to build the demand that oneself content sheds establishment, but at present retail business other people sorts development two big problems face in construction: It is premise of land sell one's own things be with link up with of apanage taxation pay, ask enterprise fractionation is registered, bring about business management difficulty to increase; 2 it is content shedding setting of condition of the sell one's own things that use the land is taller, bring about company project to build difficulty bigger.

目前国内零售企业已经形成大型国内连锁与区域性连锁等多形态连锁模式，其巨大的物流配送现状注定了建设自有物流设施的需求，但是目前零售企业物流开发建设中面临两大问题：一是土地出让前提是与属地税收缴纳挂钩，要求企业拆分注册，导致企业管理难度加大；二是物流用地出让条件设置较高，导致企业项目建设难度较大。

Analyses of spectral structure and surface tension of solutions suggest that the hydrophobic hardrocarbon chain of surfactants was partly included in the apolar cavity of β-CD and the part with the polar head group of hydrocarbon chain located outside the cavity coiled over the top of β-CD, providing an effective protection for RTP.

组成测定表明溶液中形成了稳定的1：1：1/1-BrN：β-CD：AS三元包合物。光谱和溶液表面张力分析显示阴离子表面活性剂的疏水性烷基链有一部分被包合在β-CD空腔内，未被包合部分则绕曲在β-CD腔口处从而为空腔内1-BrN分子的磷光提供了有效保护。

Finally, the paper studies the value of supply chain coordination and the appraisement of supply chain coordination.

论文最后研究供应链协调的价值和协调的评价。

The distributions of the chain radius of gyration and the two-dimensional asphericity are measured. It is found that the DNA molecules exhibit highly anisotropic shape even for circular-form and the mean asphericity is chain length independence.

从测量二维的鍊回旋半径分布发现DNA分子展现高度的非等向性的形状(甚至是环形的DNA也具备此特性)且此特性与鍊长无关。

The demand information asymmetry is common in supply chain and is one of the main factors to low efficiency of supply chain.

需求信息不对称是在供应链合作中普遍存在的现象，是导致供应链效率下降的主要因素之一。

A historical region of southwest France between the Pyrenees and the Garonne River. The duchy of Aquitaine was joined with France after the marriage of Eleanor of Aquitaine to King Louis VII in1137, but its possession was disputed after her subsequent marriage to Henry II of England.

阿基坦法国西南部一个历史地区，位于比利牛斯山和加隆河之间，在1137年阿基坦的埃莉诺与国王路易斯七世结婚之后阿基坦公国加入法国，但当她再嫁英国亨利二世后，其归属权便受到争议

There are moments when I look at the smiling , happy faces of my expectant staff and wonder how they will cope when confronted by an outraged housemaster along with an unrepentant and recalcitrant bleached blond teenager in 18 years ' time .

有时候，我看着那些满怀期待的员工微笑，幸福的脸，想着当他们遇到一位愤怒的宿舍管理员和一位不知悔改，叛逆，而且将头发染成白色的18岁少年时，他们会如何处理。