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Results The activation of NF-κB, proliferation response, and expression of IL-4 and I L-5 mRNA and protein in T lymphocytes stimulated by PMA were significantly hig her than those of their blank control (P.01), while those indexes of T l ymphocytes stimulated by PMA and PDTC simultaneously were significantly lower th an those stimulated by PMA alone (P.01). The apoptotic index of T lympho cytes stimulated with PMA were significantly lower than that of their blank cont rol (P.01), and the apoptotic index of asthmatic guinea pig T lymphocytes stimulated with PMA and PDTC simultaneously were significantly higher than that stimulated by PMA alone (P.01). The significant positive correlations w ere found between the activation of NF-κB and the proliferation (r=0.64, P.001), and the expression of IL-4 and IL-5 mRNA and protein of T lymph ocytes, respectively (r=0.55-0.68, P.001). There was also signific ant negative correlation between the activation of NF-κB and apoptosis of T l ymphocytes (r=0.62, P.001). Conclusions NF-κB may participate in the signal conduction of PKC regulated proliferation, apoptosis and expression of IL-4 and IL-5 of T lymphocytes in asthma.

结果加入PMA培养的哮喘组T淋巴细胞NF-κB的活化、细胞增殖反应、IL-4和IL-5的mRNA和蛋白质的表达均显著高于其空白对照(P.01),而同时加入PMA和PDTC培养的哮喘组T 淋巴细胞以上指标均显著低于只加入PMA培养的哮喘组T淋巴细胞(P.01);加入PMA 培养的哮喘组T淋巴细胞的凋亡指数显著低于其空白对照(P.01),而同时加入PMA 和PDTC培养的哮喘组T淋巴细胞凋亡指数显著高于只加入PMA培养的哮喘组T淋巴细胞(P 。01)。T淋巴细胞NF-κB的活化与增殖反应呈显著正相关(r=0.64,P.00 1),与IL-4和IL-5的mRNA和蛋白质的表达也均呈显著正相关(r=0.55-0.68,P 。001),而与凋亡指数呈显著负相关(r=-0.62,P.001)。

The simulation results shows that when the hydroforming for real axle housing needs two bulge processes and the specific value of the two bulge ratio is about 1, the result is the best one; To obtain an appropriate route of loading force need adjust internal pressure and axial compression force for many times and according to the failure, the size of the two forces which has been mentioned can be rapidly and rationally adjusted; Because of good greasing conditions influencing largely, reducing the friction between tube blank and die inside surface as well as possibly not only makes more materials flow into the bulge area but effectively diminishes the axial compression force; The good or bad characteristics of tube blank material is also one of the decisive factors and when material is selected, we first consider its' formability.

模拟结果表明,当后桥壳需要两次进行胀形,两次胀形比比值约等于1时,胀形结果最好;合适的加载路径要经过多次调试,能根据胀形缺陷对内压力和轴向力的大小进行迅速地合理调整;良好的润滑环境对后桥壳液压胀形的影响巨大,要尽量减小管坯与模腔内壁的摩擦力,不但使更多的材料流入胀形区,而且能有效的降低轴向力的大小;管坯材料性能的好坏也是影响胀形的决定性因素,选材时首先要考虑材料的成形性。

Try to explain. 1 "..."-- bring with " charm " a landscape painting, total meeting stays have " scanty can trot along on horseback the space of ", blank, this meeting receives " to just be like have not to wear Chinese ink place, mist-covered water is vast the artistic effect; of the " before see everywhere a moving composition, always can stay have abruptly " is silent the time of " of "" all are mute is blank, can let audience produce to leave a lasting and pleasant impression

加以诠释。1 &……&——引之以&韵&一幅山水画,总会留有&疏可走马&的空间、空白,这会收到&恰似未曾着墨处,烟波浩淼满目前&的艺术效果;一首动人的乐曲,总是会留有骤然&休止&&万马齐喑&的时间空白,能让听众产生余音绕梁

Main Products: African valuable floor blank: AFROMOSIA (commonly known as the United States and pigeon peas), PANGA PANGA, MKURUTI, MKARATI at the same time supply of these four species of sheet metal and generous, and Sudan to provide the African teak (age 60), receiving orders, while the floor can provide blank spot.

主营产品:非洲名贵地板坯料:AFROMOSIA、PANGA PANGA、MKURUTI、MKARATI同时供应以上四个品种的板材和大方,并且提供非洲苏丹柚木(60年树龄),接受订货,同时地板坯料可以提供现货。

The establishing method of stamping tools and blank finite element model are studied. Some approachs which make simulation model construction accurate and rational are proposed. The definition methods of blank holder force, punch velocity and lubrication condition are elaborated.

研究了覆盖件模具、坯料的有限元模型建立方法和提高仿真建模准确性、合理性的途径;阐述了如何设置压边力、凸模速度、润滑等工艺条件。

"Trailer" can also mean: extra blank film at the end of a film strip for winding it off in a camera or projector; extra blank film at the beginning is called "leader".

trailer&这词来源于预告片最先是在一部影片的片尾播出,这种播出方式没有持续多久,因为观众在影片结束后即要离开影院,尽管如此,&trailer这个名词延续了下来。

But utility time of this technology is not long at home, in addition, the majority of equipment is two-hand at home, and the craft technology was not introduced with it, so the people's understanding is limited to cast the copper alloy blank using the horizontal continuous casting method, the basic data lacks extremely, the copper alloy materials blank's quality is unstable, more than all, the research to the key component Graphite Crystallizer is insufficient, it affected the application of horizontal continuous casting in a certain.

但这一技术由于国内使用的时间不长,加之国内引进的大多数是二手设备,对工艺技术没有进行引进,因而人们对铜合金带坯的水平连铸生产方法认识有限,基础资料十分缺乏,生产的坯料质量不稳定,特别是对关键部件石墨结晶器研究不够深入,在一定程度上影响了水平连铸方法在铜合金带坯生产中的应用。

Based on the trial of two different heat treatment processes for TP321 tube blank ,this paper revealed influence of solution treatment and solution treatment plus stabilization treatment on room temperature tensile strength,elevated temperature tensile strength,microstructure and grain size of TP321 tube blank .

通过对 TP321管坯材料的热处理工艺试验,阐述了材料经固溶处理和固溶处理+稳定化处理这二组热处理工艺后对材料室温和高温拉伸性能、组织和晶粒度的影响。

Casting a blank on a number of ways such as the widening of steel, pushing steel machine, transferring vehicles, lifting hook contrast, the final choice of transferring to this car as a blank device.

在对连铸出坯的几种方式如拉钢机、推钢机、横移台车、起重吊钩的对比后,最终确定选用横移台车作为此出坯装置。

If the blank certificate is not enough, they should make an application by filling in Subscription List for Blank Certificate 20 days in advance.

各发证机构的空白证书不得相互借用,如空白证书使用数量不足,应提前二十天填写《空白证书征订单》,提出申请。

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Since historical times,England ,where the early inhabitants were Celts, has been conquered three times .

从有历史以来,英国,在此地早期居住的是凯尔特人,已经被征服了三次。

Bluetooth OBEX File Transfer Enables the sending and receiving of files on your phone via Bluetooth.

蓝牙OBEX文件移动允许经过蓝牙传送和接受文件。。。。

The almost sure central limit theorem is a pop topic of the probability research in recent years,because it has many actual applications in the random analogue.

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