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Five models were used to investigate the "Changdong"" s anti-tumor effect: mice S180 sarcoma solid model, mice liver cancer H22 solid model, mice Lewis lung cancer model, as well as human liver cancer QGY and colon cancer LOVO implanted in naked mice; mice liver cancer H22 was also used to evaluate the enhancive effect of "Changdong" when it was co-applied with other anti-tumor agent or with radiotherapy; The "Changdong"" s cytotoxic effect in vitro on such tumors as QGY, LOVO, lung cancer A549, breast cancer MCF-7, as well as mice leukemia P388 was observed through MTT method. And investigate the effect of "Changdong" on proliferation of spleen lymphocyte, on activity of NK cell and on synthesis of IL-2 in mice bearing Lewis lung cancer, respectively. With propidium iodide straining, cell aigptosis and cell circle were analyzed by flow cytometry. Result:"Changdong" has an evident tumor inhibitive effect on mice tumor model as well as human tumor implanted in naked mice with a quantity-effect relationship.

使用小鼠S180肉瘤、小鼠肝癌H22实体瘤和小鼠Lewis肺癌模型，以及人体肝癌QGY和人体肠癌LOVO裸鼠异种移植模型，进行"长动"的抗肿瘤药效学研究：用小鼠肝癌H22进行"长动"合并放疗和化疗的增效作用研究；用MTT法进行"长动"对肝癌QGY、肠癌LOVO、肺癌A549、乳腺癌MCF-7、小鼠白血病P388等10株人体和动物肿瘤细胞的体外细胞毒性作用研究；用淋巴细胞转化试验、小鼠NK细胞活性试验、小鼠胸腺细胞增殖法分别测定"长动"对荷Lewis肺癌小鼠的脾淋巴细胞增殖的影响、自然杀伤细胞活性的影响和对小鼠产生白介素-2(IL-2)的影响；用流式细胞仪PI单染色法进行"长动"对人体肝癌QGY细胞的体外诱导凋亡作用和对肿瘤细胞周期的影响的研究。

Second, transient flow for vertical well and fractural well in porous media with arealanisotropy has been researched in this paper. The analytic solution for vertical well andsemi-analytic solution for vertical fractural well is developed by using image inversion,superposition principle, Laplace transformation, Fourier transformation, as well as theirinverse transforms, and storage and skin are taken into account. For vertical fractural well,influence of pressure and productivity is studied when the orientation of artificial fractureisn't in accordance with the direction of major permeability, it is fundamental to evaluatepotential and analyze well test data.

文中研究了平面各向异性储层不定常渗流问题，建立了平面各向异性储层交叉直线边界中一口直井渗流的数学模型，利用镜像反演、Laplace变换、Fouier变换及其反变换推导了不同边界条件下直井的Laplace空间解析解，考虑井储和表皮的影响，分析了曲线特征及影响因素的敏感性曲线；并运用影响椭圆及Duhamel叠加原理，推导了平面各向异性储层中垂直裂缝井的压力分布方程，考虑了水力裂缝与主渗透率轴成一定角度对压力及产能的影响，为垂直裂缝井的产能评价及试井分析提供依据。

Well, after his Astonishment was a little over at this, I pointed to him to run and fetch the Bird I had shot, which he did, but stay'd some Time; for the Parrot not being quite dead, was flutter'd away a good way off from the Place where she fell; however, he found her, took her up, and brought her to me; and as I had perceivd his Ignorance about the Gun before, I took this Advantage to charge the Gun again, and not let him see me do it, that 1 might be ready for any other Mark that might present; but nothing more offer'd at that Time; so I brought home the Kid, and the same Evening I took the Skin off, and cut it out as well as I could; and having a Pot for that purpose, I boil'd, or stew'd some of the Flesh, and made some very good Broth; and after I had begun to eat some, I gave some to my Man, who seem'd very glad of it, and lik'd it very well; but that which was strangest to him, was, to see me eat Salt with it; he made a Sign to me, that the Salt was not good to eat, and putting a little into his own Mouth, he seem'd to nauseate it, and would spit and sputter at it, washing his Mouth with fresh Water after it; on the other hand, I took some Meat in my Mouth without Salt, and I pretended to spit and sputter for want of Salt, as fast as he had done at the Salt; but it would not do, he would never care for Salt with his Meat, or in his Broth; at least not a great while, and then but a very little.

这不由得使我经常想到，上帝对世事的安排，自有其天意，在其对自己所创造的万物的治理中，一方面他剥夺了世界上许多生物的才干和良知，另一方面，他照样赋予他们与我们文明人同样的能力，同样的理性，同样的感情，同样的善心和责任感，也赋予他们同样的嫉恶如仇的心理；他们与我们一样知道感恩图报，诚恳待人，忠贞不渝，相互为善。而且，当上帝给他们机会表现这些才干和良知时，他们和我们一样，立即把上帝赋予他们的才干和良知发挥出来做各种好事，甚至可以说比我们自己发挥得更充分。对此，我不能不感到惊讶。同时，想到这些，我又感到有些悲哀，因为许多事实证明，我们文明人在发挥这些才干和良知方面，反而显得非常卑劣。尽管我们不仅有能力，而且，我们受到上帝的教诲，上帝的圣灵和上帝的语言的启示，这使我们能有更深刻的认识。同时，我也感到奇怪，为什么上帝不给这成千上百万的生灵以同样的教诲和启示，使他们懂得赎罪的道理。我觉得，如果我以这可怜的野人作为判断的依据，那么，他们实在能比我们文明人做得更好。

Having studied the relation of oil well paraffine precipitation and the rod load, the paper finds one new method to predict the oil paraffine precipitation ---statistics comparison of the indicator diagram, and calculates the paraffin removal cycle as well as the paraffin removal time And predicts the oil well paraffin precipitation; Combined with the test data of oil field and the basic production parameter of the oil well system, the paper has carried on close analysis of the efficiency of the single well system, and obtained each target reflecting the system operation; the efficiency of the oil pumping mechanical well system has been improved and the submersion pressure mathematical model has been completed, and the author draws up the dynamic control chart of sub-area system efficiency, thus raises the management level in the oil well system efficiency.

通过研究油井结蜡速度与抽油机悬点载荷的关系，将油井结蜡与示功图结合到一起，找到一种对油井结蜡预测的新方法——示功图统计对比法，计算出清蜡周期与清蜡时间，预防了油井蜡卡；以现场示功图为依据，结合生产参数对抽油机井系统效率进行实测分析，完善系统效率与沉没压力的数学模型并绘制油井系统效率动态控制图，对系统效率进行了检测评价与优化。

Four aspects of research achievements include:(1)several imaging correction methods and strained estimation methods for biological tissues elasticity imaging were investigated as well as elasticity reconstruction and phantom, in vitro and in vivo elasticity imaging experiments;(2)in the fields of biological microsystem and perfusion evaluation for microvascular system, three kinds of microbubbles whose shell are albumin, sugar ester and surfactant respectively were designed and produced, then the methods to estimate the thickness of their shells were presented, moreover, the interacting mechanism of ultrasound contrast agents and tissues, as well as protein drug delivery under the condition of ultrasound sonification were studied in the molecular level;(3) At the aspect of high intensity focused ultrasound therapy system, we designed and constructed the 256-element HIFU transducers using 1-3 composite materials. And furthermore we developed the integrated HIFU system with 256-element HIFU transducers. And we made preliminary and important progresses in the research of HIFU bioeffect, lesion estimation, techniques of monitoring and imaging and characterizing of structure of HIFU transducer;(4)The real-time method of voice source regeneration based on compensative regulation of physiological parameters was investigated in the field of medical rehabilitation. We addressed the physiology and biophysics of vocalization, modeled voice source regeneration based on compensative regulation mechanism, and put forward an integrated evaluation about the speech rehabilitation and the regenerated voice source; Sixty-one archived journal papers were published, as well as ten in international journals, and eighteen publications were embodied by SCI.

成果包括：（1）在生物组织弹性成像方面，研究了多种图像校正方法和应变估计方法，进行了弹性重构和仿体、离体及在体超声弹性成像实验研究；（2）在生物微系统和微血管血流灌注成像方面，制备了三种不同包膜超声造影微泡，研究了纳米包膜厚度检测与估计方法以及不同纳米包膜造影微泡断裂与药物释放机制，并在分子层次上开展了超声与生物组织相互作用机制以及蛋白质药物超声乳化微囊包裹的研究；（3）在阵列式高强聚焦超声治疗与监控成像技术方面，设计制作了新的HIFU换能器，解决了256阵元单焦点和多焦点合成HIFU治疗系统关键技术问题，并在HIFU生物效应与创伤性评价方法、HIFU过程监控成像技术和薄层复合结构与HIFU 换能器界面特性评价等方面的研究取得了初步而重要的进展，具有重要应用前景；（4）在语音听觉系统特别是嗓音康复方面，研究了基于发声系统补偿调节机制的实时多模式嗓音源再生方法和发声生理，建立基于神经、肌肉和空气动力系统的综合补偿调节模型，提出了相应的评价系统。

Four aspects of research achievements include:(1)several imaging correction methods and strained estimation methods for biological tissues elasticity imaging were investigated as well as elasticity reconstruction and phantom, in vitro and in vivo elasticity imaging experiments;(2)in the fields of biological microsystem and perfusion evaluation for microvascular system, three kinds of microbubbles whose shell are albumin, sugar ester and surfactant respectively were designed and produced, then the methods to estimate the thickness of their shells were presented, moreover, the interacting mechanism of ultrasound contrast agents and tissues, as well as protein drug delivery under the condition of ultrasound sonification were studied in the molecular level;(3) At the aspect of high intensity focused ultrasound therapy system, we designed and constructed the 256-element HIFU transducers using 1-3 composite materials. And furthermore we developed the integrated HIFU system with 256-element HIFU transducers. And we made preliminary and important progresses in the research of HIFU bioeffect, lesion estimation, techniques of monitoring and imaging and characterizing of structure of HIFU transducer;(4)The real-time method of voice source regeneration based on compensative regulation of physiological parameters was investigated in the field of medical rehabilitation. We addressed the physiology and biophysics of vocalization, modeled voice source regeneration based on compensative regulation mechanism, and put forward an integrated evaluation about the speech rehabilitation and the regenerated voice source; Sixty-one archived journal papers were published, as well as ten in international journals, and eighteen publications were embodied by SCI.

中文摘要：成果包括：（1）在生物组织弹性成像方面，研究了多种图像校正方法和应变估计方法，进行了弹性重构和仿体、离体及在体超声弹性成像实验研究；（2）在生物微系统和微血管血流灌注成像方面，制备了三种不同包膜超声造影微泡，研究了纳米包膜厚度检测与估计方法以及不同纳米包膜造影微泡断裂与药物释放机制，并在分子层次上开展了超声与生物组织相互作用机制以及蛋白质药物超声乳化微囊包裹的研究；（3）在阵列式高强聚焦超声治疗与监控成像技术方面，设计制作了新的HIFU换能器，解决了256阵元单焦点和多焦点合成HIFU治疗系统关键技术问题，并在HIFU生物效应与创伤性评价方法、HIFU过程监控成像技术和薄层复合结构与HIFU 换能器界面特性评价等方面的研究取得了初步而重要的进展，具有重要应用前景；（4）在语音听觉系统特别是嗓音康复方面，研究了基于发声系统补偿调节机制的实时多模式嗓音源再生方法和发声生理，建立基于神经、肌肉和空气动力系统的综合补偿调节模型，提出了相应的评价系统。

Commending CR's as well as Tangshan Company's breakthrough in high-speed train development as well as the spirit of unyieldingness and determination, Wan Gang encouraged the Tangshan people to exploit the joint action plan by MOST and MOR as well as the National 11th FYP on Scientific and Technological Support, keep building innovation capabilities, step up hi-tech application and promotion and build even more advanced EMUs so as to make greater contribution to railway's equipment modernization.

万钢对铁路部门和唐车公司迎难而上、勇于登攀，取得高速动车组研制技术的重大突破表示赞赏，并勉励唐车公司广大科技人员和全体干部职工，要依托科技部与铁道部签署的两部联合行动计划和国家&十一五&科技支撑计划，不断提高企业自主创新能力，加快高新技术成果的转化和推广应用，制造出更加先进的高速动车组，为铁路技术装备现代化作出新的更大贡献。

Through the star communication network of VSAT Ku wave band was set up and linked with distance-controlled telephone network at the base, so as to realize the free communication between production unit field and management department at base, at same time, by using the information system of exploration production. it is realized that the specific data processing such as log profile along with drilling well, well logging curves, playback of log second data, real lime data of log instrument, and oil-testing data, geophysical data as well as web releasing function, with the geological data, the daily report of drilling well and oil-testing released onsite together, the dynamic information platform of exploration management has been established, which provides leaders at various level, research personnel and managers with an integrated, abundant data, dynamic information platform along with drilling.

通过建立VSAT Ku波段星状通讯网络，并将其与基地程控电话网络相连，一方面实现了野外生产单位与基地通讯的畅通；另一方面，应用勘探生产信息系统实现随钻录井剖面图、测井曲线、录井秒数据回放、录井仪实时数据及试油、物探资料等专业数据的处理及Web发布功能，与现场生产传输系统发布的地质、钻井、试油日报共同作为勘探动态管理信息平台，为基地各级领导、研究人员、管理人员提供了一个集成的、具有丰富资料的井场随钻动态信息平台。

Content included: study on the relationship between noise and cumulative noise exposure as well as low frequency noise-induced hearing loss and high frequency noise-induced hearing loss; study on the relationship between noise sensitivity as well as LFNIHL and HFNIHL.1 Study on the relationship between noise and CNE as well as LFNIHL and HFNIHL657 data concerning workers' hearing check-up were collected including such types of work as Trial pilots and Riveters.

内容包括：噪声和累积噪声剂量与语频和高频听力损伤关系的研究；噪声敏感与语频和高频听力损伤关系的研究。 1 噪声和累积噪声剂量与语频和高频听力损伤关系的研究选取成都某大型飞机制造厂试飞和铆工两个工种作业人员657名作为研究对象。其中试飞员199人(均为男性；年龄23～60岁，平均37.36岁；接噪工龄1～42年，平均接噪工龄17.68年)。

It is concluded in Chapter Eight that: 1 linguistic proficiencies in three languages play a considerable part in code-switching of EFL teachers in trilingual context; the inter-sentential switching outweighs the intra-sentential switching both in frequencies and percentage; discourse-related switching also outweighs participant-related switching in frequencies and percentage; the EFL is maintained longest in EFL classroom and the language maintained second longest depends upon learners" higher proficiency in Chinese or Tibetan. 2 Ethnic identity and educational background is the major causal factor of EFL teachers" Chinese-English switching in trilingual classroom; duration of language contact and relative trilingual proficiencies are the two principal contributors to the English-Tibetan switching; while Tibetan-English switching is mainly driven by EFL teachers" ethnic identity and education background, as well as the duration of language contact; English-Chinese switching is also largely motivated by the duration of trilingual contact; and Chinese-Tibetan switching is determined by trilingual proficiency to a considerable extent. Meanwhile, psychologically, the switching is mainly motivated by a procedure of psychological projection, trilingual system conceptualization and the mentality of trilingual selection. 3 The educational reflections upon this study indicate: firstly, in trilingual context, the teachers" classroom discourse is characterized by the multilingual involvement, flexibility in strategy option as well as the extension and strengthening of the domination of teachers" discourse. Secondly, the discourse movement and code-switching are largely affected by two cultural ecological mechanisms: enculturation and cultural manipulation. Thirdly, the status quo of EFL trilingual teachers are characterized by unbalanced trilingual proficiencies, poor cultural awareness, and little knowledge of trilingual education and trilingual code-switching, therefore, suggestions are advanced in the end to provide them further education. Fourthly, in trilingual context, the EFL curriculum for ethnic minorities is characterized by plurality of aims, complexity of organization and variety of resources. Meanwhile, it is of great necessity to understand the linguistic values of EFL education for ethnic minority learners. To be specific, firstly, we should not only have a deep understanding of the distribution, construction, function as well as communicative effects of the three languages, but also have a comparative study of the three languages and thus provide the standardization and guidance for the trilingual education. In the end, it is advanced that trilingual EFL provision for ethnic minority should pursue to develop learners" multicultural value system in which first language culture and mother language culture take the central position and EFL culture plays a vital role.

3在三语环境下，教师课堂话语具有话语形态多元化、话语选择策略具有灵活性和教师话语权得到延伸和拓展等特征；文化涵化和文化操控是影响三语教师课堂语码转换的两种文化生态机制；参差不齐的三语水平、淡薄的多元文化意识和对三语教学和语码转换缺乏科学认识是我国目前三语师资的主要特点，因此应对三语教师进行职后继续教育；在三语环境下，民族外语课程具有课程目标多元化、课程组织复杂化和课程资源多样化等特点；应对民族外语教育的语言价值进行审视和解读，对三种语言在课堂话语中的分布趋势、结构特征、功能作用和交际效果等问题进行深入研究，加强对三种语言间的对比分析研究，同时对民族外语教育中的三语教学进行规范和指导；在强调民族文化和二语文化在三语文化格局中心地位和外语文化的重要作用的同时，民族地区的外语教育应以构建多元文化价值观为其文化追求。

I'm strongly against the death penalty — it's an eye for an eye.

我不赞成死刑——这是以牙还牙的报复行为。

And to get you the support you need, we're enlisting all elements of our national power: our diplomacy and development, our economic might and our moral suasion, so that you and the rest of our military do not bear the burden of our security alone.

并给你们所须的支援，我们正徵召国家所有各种的力量：我们的外交及发展，我们的经济力量与道德劝说，所以你们与其他军人不须要孤独地负起国家安全的责任。