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马钱苷

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Cornus officinalis ; juice ; loganin ; reversed-phase high performance liquid chromatograph ; quality control

山茱萸;果汁;马钱苷;反相高效液相色谱法;质量控制

OBJECTIVE To establish a method for the determination of loganin in Xiaohe oral solution.

目的 建立测定消核口服液中马钱苷的方法。

Results The contents of loganin and morroniside was higher than 98% by normalization method of HPLC.

结果所得马钱苷和莫诺苷用归一化法定量,质量分数均大于98%。

Objective To establish a separation method of loganin and morroniside reference substance from Fructus Corni.

目的研究从山茱萸中制备马钱苷和莫诺苷对照品的方法。

Objective To establish a separation method of loganin and morroniside reference substance from Fructus Corni.

目的 研究从山茱萸中制备马钱苷和莫诺苷对照品的方法。

Loganin and morroniside were identified by UV, 1H-NMR, 13C-NMR, and MS.

结果所得马钱苷和莫诺苷用归一化法定量,质量分数均大于98%。

The purification of iridoid glycosides was evaluated with contents of morroniside and loganin by HPLC methods.

以洗脱液中莫诺苷和马钱苷含量作为考察指标,用 HPLC法测定其含量,确定最佳工艺参数。

The developed method is simple with lower cost, by which loganin and morroniside can be used as reference substances for the qualitative and quantitative analysis of Chinese herbal medicine.

结论本法简便,制备成本低,所得马钱苷和莫诺苷可作为中药定性、定量分析使用的对照品。

Results The contents of loganin and morroniside was higher than 98% by normalization method of HPLC. Conclusion The developed m...

结论本法简便,制备成本低,所得马钱苷和莫诺苷可作为中药定性、定量分析使用的对照品。

In the light of looking up -finishing-inquiring into the literature,The subject ntegratedly applied the knowledge of botany and phytotomy and Authentication of Chinese Medicines and the experimental technology to study taxonomy and anatomy of Cornus chinense Wanger and its kindred plant.To combine the knowledge of natural medicinal chemistry instrumental analysis,pharmaceutical analysis and experimental technique,Glycosides chemical components of Cornus chinense Wanger and its kindred plant were qualitatively analysised by using TLC.

以文献查阅-整理-调查为基础,综合运用植物学、植物解剖学、中药鉴定学知识与实验技术对川鄂山茱萸及其近缘植物进行分类学处理与解剖学研究,结合天然药物化学、仪器分析、药物分析等学科的知识与实验技术,用TLC定性分析川鄂山茱萸及其近缘植物的苷类化学组分;用HPLC测定川鄂山茱萸不同器官、细胞组织、果实不同采集期的熊果酸、马钱苷的含量并进行色谱条件优化。

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