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RNAi therapeutics target the cause of diseases by potently silencing specific messenger RNAs, thereby preventing disease-causing proteins from being made.

RNA干扰治疗的目标的原因疾病potently沉默特定的信使核糖核酸,从而防止致病蛋白质正在取得进展。

Two other missense mutations (G288R and 711D) and a 1944-bp genomic deletion coding for exons 16 to 19 in the FLNA gene were identified in 3 additional, smaller, unrelated families affected by alular dystrophy, which demonstrates the responsibility of FLNA as a cause of XMD.

在另外3个患瓣膜营养不良症非该家族成员中,我们证实有两个编码外显子16和19的基因错义(G288R和711D)和一个基因缺失。这证明FLNA是XMD的致病重要原因。

Pulmonary microvascular endothelial cells, one of pivotal effective cells against pathopoiesis factor in early stage of disease, are proved to play an important role in mediating inflammatory response, aggravating tissue hypoxia, and secreting cytokines and matrix to regulate the migration, proliferation and differentiation of mesenchymal cells.

然而,它在消除致病因子对机体损伤的同时也可能由于某种原因而过度地发挥了介导免疫、炎症反应,加重组织缺氧,分泌过量细胞因子等生物学作用,从而促进了组织的纤维性修复。

PartⅠGenistein thwarts the development ofatherosclerosis in LDLR-knockout mice BACKGROUND: Artherosclerosis and its complication are one of the maincauses for pathopoiesis and death.

第一部分Genistein对LDLR-/-小鼠动脉粥样硬化发生发展的影响研究背景动脉粥样硬化(artherosclerosis,AS)及其并发症是人群致病和死亡的重要原因之一。

objiective:to investigate the causes of the contamination of dialysis fluid.methods the level and species of bacteria were detected.results:the pathopoiesis bacteria and pathopoiesis bacteria in condition were identified in dialysis fluid,fluid b.offlake of soft water and preparing container.conclusions the contamination of'dialysis fluid is related with the untimely change of the filter in soft water machine and membrane of reverse osmosis,the contamination of fluid b.

目的:调查透析液和透析用水细菌污染的原因。方法:按《医院感染管理规范》的要求检测并鉴定致病菌。结果:透析液和透析用水、b液、软水口、配液容器培养出致病菌和条件致病茵。结论:血液透析液和透析用水细菌污染与软水机过滤器和反渗膜使用时间过长引起破损,未能及时更换,以及b液配制过程中细菌污染有关。

the low procreant routeway infection is one important reason to abortion in prevalence.through enhance pertinence treatment to microbe which can cause disease,it might reduce the quotiety of abortion in prevalence.

孕期下生殖道感染是引起孕妇早产的一个重要原因,加强对其中一些高致病性微生物针对性的治疗,可能对减少早产的发生起到重要作用。

A few percentage of Rhodococcus equi (1.9%) were also found. The cause about high value of pH T-VBN TVC and the latent disease hazards of survival bacteria flora should be further surveyed.

产品pH值、T-VBN值、菌落总数较高的原因和残存细菌的潜在致病性危害有待进一步研究。

In this study, the researchers were looking at a population with high rates of disease-causing gene mutations to investigate genetic causes of deafness.

在这份研究中,研究人员研究带有大量致病基因突变的人,来调查失聪的原因。

First, the western medicine denounced that the herbalist doctor didn\' t anatomise body and they didn\' t find the reason causing the disease , so they didn\' t cured patients at all.

西方医学首先以解剖学为根据攻击中医,指出只有解剖,亲视人体脏腑,才能找出致病的原因,治病也才有效果,但是中医却没有解剖,因此治病的那一套方法根本无所凭据。

Zhongshu 4. They performed mild mosaic and synergism instead. Different ToMV-N5-induced symptoms in two varieties may be the primary reason of dissimilar ToMV-N5 infections mediated by CMV-Fny.

ToMV-N5在两个番茄品种上引起的症状差异可能是导致CMV-Fny对其致病产生不同调控作用的原因。

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He and Nina moved to California and lived at 2005 Ivar Street, Apt.

他和Nina搬到加州,并在2005年伊瓦尔街,公寓生活。

Droperidol ( potently inhibits transfected HERGchannels and this is the probable mechanism for QT prolongation.

氟哌利多有效地抑制了转染的 HERG 钾通道,可能是 QT 间期延长的机制。

The Nazi's cruel treatment of the Jews during the Second World War is beneath contempt .

二战期间纳粹对犹太人的暴行极其可鄙。