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A new synthesis method of Taxane s was reported involving radicals generated from hypophosphorous acidn initiated by 2,2′-azobisisobutyronitrile.

由偶氮二异丁腈引发次磷酸产生次磷酸根自由基,以链式自由基反应机制脱除紫杉烷类化合物结构中的含氧基团,简单、高效地合成了紫杉烷。

A new synthesis method of Taxanes was reported involving radicals generated from hypophosphorous acid n initiated by 2,2′-azobisisobutyronitrile.

由偶氮二异丁腈引发次磷酸产生次磷酸根自由基,以链式自由基反应机制脱除紫杉烷类化合物结构中的含氧基团,简单、高效地合成了紫杉烷。

Since 2007, the company has integrate the breeding of Taxus Madia, the extraction, research, development and production of taxol.

进入2007年以来,公司已将曼地亚红豆杉的繁育、紫杉醇的提炼、紫杉醇酒的研制、开发、生产一体化。

The result showed that sodium orthovanadate had a increasing effect on the paclitaxel content of cell cultures.

结果表明,钒酸钠对红豆杉悬浮培养的紫杉醇合成有明显的促进作用,添加50 μmol/L的钒酸钠使细胞的紫杉醇含量增加了71.3%。

Paclitaxel was first isolated from Taxus brevifolia Taxaceae in the sixties from last century, and its derivative Taxotere1 was clinically introduced 30 years later for the treatment of mainly ovarian and breast cancers.

紫杉醇是在其衍生物taxotere1在临床上用于治疗卵巢癌和乳癌后30年于上个世纪六十年代首次从紫杉属红豆杉科中分离得到的。

The wood anatomical feature,the size of tracheid and L/D were measured and studied by the method of comparitive analysis.It was also measured for the airdry density,coeffecient of shrinkage,Chemical composition of Taxus cuspidata.

运用对比分析的方法对紫杉木材的解剖特征、管胞的大小、长宽比等进行了较详细的测定与分析;对紫杉木材的气干密度、干缩系数、化学成分进行了测量。

Paclitaxel can synergistically inhibit the proliferation of OC〓 with the combination of curcumin; The combination of curcumin and paclitaxel show enhanced the effect and put down the by-effect in chemotheapy.

紫杉醇可与姜黄素协同抑制人卵巢癌细胞系OC〓的增殖;紫杉醇与姜黄素的联合化疗有增效减毒作用。

By the study of elicitors' action mode on Taxol biosynthesis, their action point in Taxol biosynthesis pathway an...

本文通过对诱导子促进紫杉醇合成的作用模式研究,推导诱导子在紫杉醇合成途径上的作用部位,确定其配伍特性。

In this paper,the condition of eluant,time,feed flow,eluant fo lw are optimized and a set of optimized operation condition is given.The process flow is supplied for the purification of taxol.

同时,对紫杉醇前处理过程中洗脱液条件,随后的S M BC系统实验中的切换时间等条件进行了优化,并总结出一套优化操作条件,为纯化紫杉醇提供了合理的工艺路线。

EVA coated Paclitaxel-eluting stent can inhibite the neointimal hyperplasia in stented areas of coronary arteries one month after stent implantation in mini-swine model, which shows markeding promising of this product manufactured in Chinese factory. But the stent can also delay the reendothelialization of the intima and have the potential risk of late thrombosis as observed in studies of TAXUS stent, which suggests the importance of antipletelet therapy in clinical practice.

用该多聚物涂层制成的紫杉醇药物洗脱支架明显减少带药量的情况下可抑制1个月时猪冠状动脉新生内膜增生,均有开发、生产的前景,但和TAXUS紫杉醇洗脱支架一样可造成血管再内皮化及内膜修复延迟,且有造成晚期血栓形成的风险,提示临床应用中应加强抗血小板治疗。

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