异常兴奋的

Little Pearl- who was as greatly pleased with the gleaming armour as she had been with the glittering frontispiece of the house- spent some time looking into the polished mirror of the *plate.

小珠儿就象她刚才对宅瞪闪光的前脸大为高兴一样，此时对那明晃晃的盔甲也兴奋异常，她在擦得缀亮的护胸镜前照了好长时间。

Little Pearl- who was as greatly pleased with the gleam ing armour as she had been with the glittering frontispiece of the house- spent some time looking into the polished mirror of the breastplate.

小珠儿就象她刚才对宅瞪闪光的前脸大为高兴一样，此时对那明晃晃的盔甲也兴奋异常，她在擦得缀亮的护胸镜前照了好长时间。

Little Pearl- who was as greatly pleased with the gleaming armour as she had been with the glitter ing frontispiece of the house- spent some time looking into the polished mirror of the breastplate.

小珠儿就象她刚才对宅瞪闪光的前脸大为高兴一样，此时对那明晃晃的盔甲也兴奋异常，她在擦得缀亮的护胸镜前照了好长时间。

"On a more fundamental note, the evidence of reduction of hallucinations after magnetic stimulation over the left temporoparietal cortex may yield clues to the pathophysiology of auditory hallucinations," Dr. Aleman''s team points out.

" Aleman研究小组指出，"从一个更基础的层面考虑，磁信号刺激左侧颞顶叶皮层可以缓解幻听的事实，有可能提供幻听的病生理学线索，也就是说，减少语言识别中枢的兴奋性能够减少幻听，提示产生幻听的原因可能是因为语言识别中枢的异常活动造成。

Ultimately, vulnerable groups of neurons atrophy and die in a process that may involve excitotoxicity (overstimulation of neurotransmitter receptors on neuronal surface membranes), collapse of calcium homeostasis, inflammation, and depletion of energy and growth factors.

最终在兴奋性毒性（过度刺激神经元上的递质受体）、钙紊乱、炎症、能量和生长因子缺乏作用下，敏感的神经元发生萎缩、死亡。apoE4与Aβ和tau的异常聚集有关，还可能损伤线粒体和其他细胞骨架。Aβ、tau、apoE和synuclein与其他分子相互作用，影响多种神经活动和存活的信号转导途径。

Ultimately, vulnerable groups of neurons atrophy and die in a process that may involve excitotoxicity (overstimulation of neurotransmitter receptors on neuronal surface membranes), collapse of calcium homeostasis, inflammation, and depletion of energy and growth factors. A form of apolipoprotein E, apoE4, contributes to the abnormal accumulation of A and tau, but probably also damages mitochondria and the cellular cytoskeleton. A , tau, apoE and -synuclein interact with many other molecules and modulate diverse signalling cascades that regulate neuronal activity and survival.

最后，易感神经元会萎缩直至死亡，原因可能有兴奋性中毒（神经递质对神经元表面受体的过度刺激引起），钙稳态失衡，炎症反应，能量和生长因子的耗尽。apoE4的产生可导致A肽和tau蛋白的异常聚合，可能也损害线粒体和细胞骨架。A肽、tau蛋白、apoE和突触核蛋白可与很多分子反应，也可调节不同信号级联反应，这些级联反应对于维持神经元活动性和生存性意义重大。

Transgenic expression of IL-1ra and degree of audiogenic seizure of P77PMC rats were observed after infection with pHSV-IL-1ra virus (〓 virus particles) by i. c. v injection and hippocampus injection. Results show: 1. Overexpression of IL-1ra by pHSV-IL-1ra significantly inhibited seizure attacks of P77PMC rat.

实验结果提示IL-1β可导致神经细胞NMDAR mRNA表达及受体活性增加，从而使其兴奋性增高；脑中内源性IL-1系统的异常很可能是形成P77PMC遗传癫痫易感大鼠惊厥易感性的重要因素之一；我们首次构建并鉴定了pHSV-IL-lra重组质粒，并成功地进行了脑内基因转移，使P77PMC大鼠的惊厥程度明显降低。

"On a more fundamental note, the evidence of reduction of hallucinations after magnetic stimulation over the left temporoparietal cortex may yield clues to the pathophysiology of auditory hallucinations," Dr. Aleman''s team points out.

& Aleman研究小组指出，&从一个更基础的层面考虑，磁信号刺激左侧颞顶叶皮层可以缓解幻听的事实，有可能提供幻听的病生理学线索，也就是说，减少语言识别中枢的兴奋性能够减少幻听，提示产生幻听的原因可能是因为语言识别中枢的异常活动造成。

Wrong notes, tempo mistakes, meandering jams, and a stoned Ozzy Osbourne may seem like detriments, but when paired with music this ugly it gives it an endearing urgency that keeps the album interesting.

听似错误的音符、音速和其中所充斥的干扰，还有那个兴奋陶醉的Ozzy Osbourne（他对此从不否认而且异常骄傲）可能看上去是对音乐的破坏，但和音乐配合起来时，这种丑陋的音乐元素却创造出一种会另人非常喜爱的急迫感，也使专辑更加吸引听众。

Good!""Jingle bell" ringing after listening to four years, but today they appear to be so exciting exceptions, the teachers actually went into the room smiling, and she went to the podium before the students smiled and said:"The students, teachers satisfied with your performance today, please continue to work.

好的！&&叮铃铃&听了四年的铃声，但今天却显得那么异常让人兴奋，老师竟笑容满面地走进教室，她走到讲台前，笑着对同学们说：&同学们，老师今天对你们的表现十分满意，请继续努力。

I think he's learned how to approach hitters....

Johhny Damon说，『他已是最好的了，再没有人能够比他做的更好，我想他的球技已经完全成熟了，而且他也已经学会了如何去对付和压迫各种打击者。。。。。。

In effect, an 18 foot King Cobra could actually look down onto the average human being.

际上，一个18尺眼镜蛇王其实可以俯视到的平均人。