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"It's well-established that chronic alcohol abuse leads to abnormalities in brain neurobiology and neurocognitive function, and it's also been shown that smoking itself leads to neurobiological and neurocognitive dysfunction," he says.

"这是行之有效的,长期酗酒会导致异常的脑及神经认知功能它的研究还显示吸烟本身导致的神经生物学和认知功能障碍,"他说。

The relationship between the genetic deficiencies and hemorrhagic disorder were characterized. The homozygosity of the Thr359Met in the propositus with FⅦ: C activity 2% was related to severe clinical symptoms; The proband with double heterozygous lesions of Arg152Leu and one single nucleotide deletion at position 11487-9, combined with Arg304Trp in exon 8 with FⅦ activity 1% suffered severe clinical bleeding tendency. one proband with double heterozygous mutations (Agr304Trp and Arg304Gln) with 10% of FⅦ activities characterized asymptom. the heterozygous mutations (Thr359Met, Arg152Gln,-55C→T) with FⅦ: C 1%~5. 5% showed moderate or mild clinical symptoms.

其中8961 G>T(Arg152Leu)和10966-8delC两种突变为国际首次报道,IFSla+5g>a突变导致的异常剪接为国际首次报道。1个F7及F10基因联合缺陷家系,其中,F10基因28139 G>T(Val384Phe)突变为国际首次报道;发现了1个由F7及组织因子(tissue factor,TF)两种基因联合缺陷导致的出血家系,其突变分别为F7基因启动子区-55C>T杂合突变;TF 9363 C>T(Arg131Trp)杂合多态性(频率2.63%)。6种F7基因突变发生在催化区;2种突变发生在裂解位点;1种发生在启动子区;1种突变发生在剪接位点,除一种缺失突变外,其余均为点突变;所有家系的基因突变都来自先证者的父亲和/或母亲。

Based on the analysis of the impact of unofficial dollarization, semiofficial dollarization and official dollarization on the financial stability, the essay has an opinion that monetary substitution caused by highly dollarization and the central bank deprived of the function as lender of last resort will ultimately result in the vulnerability and instability of the financial system.

通过分析非官方美元化、半官方美元化和官方美元化三种不同形式对金融稳定的冲击,认为:高度美元化导致的货币替代和丧失最后贷款人功能的中央银行都将最终导致金融体系的脆弱,丧失金融稳定。

The process of the land subsidence caused by underground mining is complicated and systematicness.

地下采矿导致地面沉陷的过程是一个复杂的系统性问题,准确预测因采矿导致的地面沉陷发展趋势,对于规避其危害具有重要的现实意义。

As to the confusion of "claim" and " credit " which is resulted from the substantially coincident definitions in German Civil Law,the traditional interpretation which takes them for not only substantially coincident but also the generalspecial relationship will lead to so much theoretic bepuzzlement.

对于请求权与债权在《德国民法典》中的实质一致性界定所导致的混淆,传统上以二者实质一致且系一般与特殊关系的解释将导致诸多理论困惑,各种标准下的区分学说也因存在各种缺陷而不足以根本解决问题。

The synthetical curative effects of Yang Gan Kang Ai Wan and TACE in moderate or advanced primary liver cancer are better than TACE.Yang Gan Kang Ai Wan has the effects of assistance and suppression on TACE.It could prolongate survival period,improve the survival rate,suppress or abate the damage to hemopoietic system,liver function and hepatic fibrosis caused by TACE.

养肝抗癌丸联合TACE疗法能够有效地抑制或减轻TACE疗法导致的毒副反应,保护和改善中晚期原发性肝癌患者造血功能和肝细胞功能,拮抗TACE导致的肝纤维化损害,延长患者的生存期,提高生存率和生存质量,治疗中晚期原发性肝癌的综合疗效优于TACE疗法。

The cell adaptability tests showed that the CPE caused by wild CCV strains were different from reference strains syncytia CPE.

细胞适应性试验表明,分离到的野毒在A72细胞上导致的CPE不同于参考毒株的合胞体病变,NJ2、KM株主要导致细胞圆缩、脱落,NJ2株的6-15代在A72细胞上有CPE,但是15代后不再出现CPE。

But the dollar's relative strength weighs heavily on the results of American firms by devaluing their foreign revenues.

但是是由于美元的相对强度导致的公司国外收入的贬值导致的。

Many experts believe shark populations are destined for collapse, due to overfishing in many areas of the world and the awful practice of "finning".

许多专家认为,由于对&鱼翅&的追捧导致的全球多个地区对鲨鱼的过度捕杀,必然导致鲨鱼数量的降低。

The restrictive filling pattern is distinguished from overfilling of a normal ventricle by a reduced and delayed E' and a shortened E deceleration time that reflect slow relaxation and increased LV stiffness.

限制性充盈模式是区别二尖瓣环流速峰值减少和延缓导致的正常心室过度充盈与更短的二尖瓣血流E峰减速时间导致的正常心室过度充盈,其反映了舒张功能变得迟缓和左室室腔僵直程度的增加。

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Methods: Five patients with parkinsonism or dystonia were assigned to general anesthesia using an modified endotracheal tube.

本实验依照人体实验之相关规定进行,五位患有帕金森氏症或肌张力异常的病人接受神经立体定位手术。

If you can benefit from this book, it is our honour.

如果您能从本书获益,这将是我们的荣幸。

The report also shows that the proportion of unmarried men and women living together has doubled between 1986 and 2006, with 13 per cent of those aged 16 to 59 now cohabiting.

报告还指出,从1986年至2006年,英国未婚男女同居的比例增长了一倍,在16岁至59岁的人群中,有13%的人同居。