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From the view of thermodynamics, native complexis the structure with the lowest binding free energy.

通常热力学上认为生物分子的稳定构象是自由能最低的构象,因此,分子对接的目的就是找到能量最低的构象。

This paper intends to discuss the integration approach of corporate culture and the ideological and political work in the enterprise, to give some operable advices on it.

本文研究的目的和意义就在于探讨企业思想政治工作与企业文化对接的途径,为实现二者的有机结合提供可操作性的建议。

The paper focuses on the construct design, machining and assembling of modules. The methods for module function tests are explained, the results of tests testify the modules performance accord with the demands on them. Three kinds of reconfigurations are discussed: snake reconfiguration, pedrail reconfiguration and four-footed reconfiguration.

论文着重论述可以手动完成对接的模块的结构设计,包括三个部分的具体设计思想和方法,以及模块的加工和装配过程,说明模块功能的测试方法,测试结果表明模块性能符合预先设计的要求。

After the demand-supply curve being set up, a partial analysis is drawn into investor behavior with the conclusion that the profit maximizing portfolio is at the point where the investment budget line touches the investment indifference line, or, to be more exact, the topgallant investment bundle for any investor is when any pair of investment assets have the same marginal return.

本文采用现代经济学的分析方法尝试对证券这种虚拟资本进行研究,力求实现证券市场的产品配置与经济学基本问题研究对接的同时,主要在以下几个方面提出了一些自己的见解:证券这种特殊的产品也具有价值和使用价值,证券产品的价值不是真正意义上的价值,而是交换价值;证券产品的使用价值在子能够满足人们投资或投机的需要。

To a city bogged down in the demoralisation of worklessness, the great steel pincers nearing each other from the opposing shores must have seemed symbols of prosperity that must one day come again.

对一座因失业的消沉而沉沦的城市而言,这项由海湾两岸逐渐对接的钢铁运动在那时就被所有人都看作这城市定会再次繁荣昌盛的标志。

Then,the thesis makes comments on the value of emphyteusis both in the reform of the taxes and fees system a...

我们认为,两种制度对接的基础是两者间诸多的共同性;依据永佃权制度,现行制度下&三提五统&的征收,应以土地收益的一定比例为依据,而不是以全村农民的收入为标准;当永佃权在被赋予了物权性质的权利之后,农地主体间的利益不平衡问题,能够得到较为妥善的解决。

Using the crystal structure of CDK2 complexed with indirubin-5- sulphonate as the template, models of CDK4 complexed with indirubin and its analogue were built by homology modeling and molecular docking.

以获得晶体结构的CDK2与5-磺酸根-靛玉红的复合物为模板,通过同源模建和分子对接的方法构建出的CDK4与靛玉红及其衍生物的结合模式。

First, the significant of co-factor InsP6 and center water in the mechanism of auxins are explored by docking; second, the experiments that compared with the docking rusults of two situations involving fully rigid and selective flexible of active residue of the receptor TIR1 illuminate that selective flexibility docking by AutoDock4 reports more rational results, so that, AutoDock4 dockings are implemented with TIR1-Auxins; third, AutoDock4 docking by TIR1-Auxins-Aux/IAA illuminates that auxin as a molecular glue enhances the interaction between TIR1 receptor and Aux/IAA substrate by the weak interactions, such as hydrogen bond and hydrophobic interaction, furthermore, the weak interactions between receptor protein and ligands greatly influence on auxin activity of auxin ligands.

首先, 通过分子对接计算研究辅酶InsP6以及中心水分子在生长素反应中的重要作用;其次,比较受体大分子完全刚性以及活性残基部分柔性的两种情况下的分子对接结果,说明AutoDock4实现了受体分子活性残基的部分柔性而使对接结果更加合理,进而使用AutoDock4方法对TIR1-Auxins体系进行对接计算;最后,对TIR1-Auxins-Aux/IAA体系进行分子对接计算,结果表明,生长素配体分子作为&分子胶水&直接与受体大分子TIR1以及底物多肽Aux/IAA形成强的弱相互作用,如氢键作用、疏水相互作用,促进了受体TIR1与Aux/IAA底物之间的结合,进而说明氢键作用和疏水相互作用等弱相互作用对于生长素分子的活性具有很大的影响。

The octagonal gold butt caps each bear a classical female portrait bust in high relief surrounded by classical motifs of hands, mirrors, scale of justice and others on each of the eight sides.

八角形的黄金对接的上限,每个承担了古典女性肖像半身像在高救济包围古典图案的手,镜子,规模,司法和其他的每一项8两岸。

The complex systemic and multi-scalar capacities of cities are a massive potential for a broad range of positive articulations with nature's ecologies.

城市具有复杂的、系统的、多尺度的能力,这使城市具备了与自然生态进行广泛正面对接的巨大潜力。

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He and Nina moved to California and lived at 2005 Ivar Street, Apt.

他和Nina搬到加州,并在2005年伊瓦尔街,公寓生活。

Droperidol ( potently inhibits transfected HERGchannels and this is the probable mechanism for QT prolongation.

氟哌利多有效地抑制了转染的 HERG 钾通道,可能是 QT 间期延长的机制。

The Nazi's cruel treatment of the Jews during the Second World War is beneath contempt .

二战期间纳粹对犹太人的暴行极其可鄙。