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初步设计的模型

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The topology models of MFIand MOR were built and the method of Configurational-bias Monte Carlosimulation was used for investigating the adsorption and distributions of ethanethiolas adsorbate in MFI and MOR type zeolites. The diffusion of ethanethiol in MFI andMOR type zeolites was studied by molecular dynamics simulation.The results show, the concentration of Zn2+ is the most important factor of theloading quantity of zeolite 13X and alumina, and the temperature secondly. The pHvalue which range from 2 to 3 effects on the loading quantity faintly.

构建了MFI 和 MOR 两种拓扑结构沸石的数学模型,以乙硫醇分子作为被吸附的目标物,采用偏倚蒙特卡罗方法模拟乙硫醇在MFI和MOR沸石上的吸附行为及分子分布密度,并利用分子动力学模拟乙硫醇在这两种拓扑结构的扩散行为,为实现面向硫化物进行吸附剂的微观结构设计作初步探索。

Four aspects of research achievements include:(1)several imaging correction methods and strained estimation methods for biological tissues elasticity imaging were investigated as well as elasticity reconstruction and phantom, in vitro and in vivo elasticity imaging experiments;(2)in the fields of biological microsystem and perfusion evaluation for microvascular system, three kinds of microbubbles whose shell are albumin, sugar ester and surfactant respectively were designed and produced, then the methods to estimate the thickness of their shells were presented, moreover, the interacting mechanism of ultrasound contrast agents and tissues, as well as protein drug delivery under the condition of ultrasound sonification were studied in the molecular level;(3) At the aspect of high intensity focused ultrasound therapy system, we designed and constructed the 256-element HIFU transducers using 1-3 composite materials. And furthermore we developed the integrated HIFU system with 256-element HIFU transducers. And we made preliminary and important progresses in the research of HIFU bioeffect, lesion estimation, techniques of monitoring and imaging and characterizing of structure of HIFU transducer;(4)The real-time method of voice source regeneration based on compensative regulation of physiological parameters was investigated in the field of medical rehabilitation. We addressed the physiology and biophysics of vocalization, modeled voice source regeneration based on compensative regulation mechanism, and put forward an integrated evaluation about the speech rehabilitation and the regenerated voice source; Sixty-one archived journal papers were published, as well as ten in international journals, and eighteen publications were embodied by SCI.

成果包括:(1)在生物组织弹性成像方面,研究了多种图像校正方法和应变估计方法,进行了弹性重构和仿体、离体及在体超声弹性成像实验研究;(2)在生物微系统和微血管血流灌注成像方面,制备了三种不同包膜超声造影微泡,研究了纳米包膜厚度检测与估计方法以及不同纳米包膜造影微泡断裂与药物释放机制,并在分子层次上开展了超声与生物组织相互作用机制以及蛋白质药物超声乳化微囊包裹的研究;(3)在阵列式高强聚焦超声治疗与监控成像技术方面,设计制作了新的HIFU换能器,解决了256阵元单焦点和多焦点合成HIFU治疗系统关键技术问题,并在HIFU生物效应与创伤性评价方法、HIFU过程监控成像技术和薄层复合结构与HIFU 换能器界面特性评价等方面的研究取得了初步而重要的进展,具有重要应用前景;(4)在语音听觉系统特别是嗓音康复方面,研究了基于发声系统补偿调节机制的实时多模式嗓音源再生方法和发声生理,建立基于神经、肌肉和空气动力系统的综合补偿调节模型,提出了相应的评价系统。

Four aspects of research achievements include:(1)several imaging correction methods and strained estimation methods for biological tissues elasticity imaging were investigated as well as elasticity reconstruction and phantom, in vitro and in vivo elasticity imaging experiments;(2)in the fields of biological microsystem and perfusion evaluation for microvascular system, three kinds of microbubbles whose shell are albumin, sugar ester and surfactant respectively were designed and produced, then the methods to estimate the thickness of their shells were presented, moreover, the interacting mechanism of ultrasound contrast agents and tissues, as well as protein drug delivery under the condition of ultrasound sonification were studied in the molecular level;(3) At the aspect of high intensity focused ultrasound therapy system, we designed and constructed the 256-element HIFU transducers using 1-3 composite materials. And furthermore we developed the integrated HIFU system with 256-element HIFU transducers. And we made preliminary and important progresses in the research of HIFU bioeffect, lesion estimation, techniques of monitoring and imaging and characterizing of structure of HIFU transducer;(4)The real-time method of voice source regeneration based on compensative regulation of physiological parameters was investigated in the field of medical rehabilitation. We addressed the physiology and biophysics of vocalization, modeled voice source regeneration based on compensative regulation mechanism, and put forward an integrated evaluation about the speech rehabilitation and the regenerated voice source; Sixty-one archived journal papers were published, as well as ten in international journals, and eighteen publications were embodied by SCI.

中文摘要:成果包括:(1)在生物组织弹性成像方面,研究了多种图像校正方法和应变估计方法,进行了弹性重构和仿体、离体及在体超声弹性成像实验研究;(2)在生物微系统和微血管血流灌注成像方面,制备了三种不同包膜超声造影微泡,研究了纳米包膜厚度检测与估计方法以及不同纳米包膜造影微泡断裂与药物释放机制,并在分子层次上开展了超声与生物组织相互作用机制以及蛋白质药物超声乳化微囊包裹的研究;(3)在阵列式高强聚焦超声治疗与监控成像技术方面,设计制作了新的HIFU换能器,解决了256阵元单焦点和多焦点合成HIFU治疗系统关键技术问题,并在HIFU生物效应与创伤性评价方法、HIFU过程监控成像技术和薄层复合结构与HIFU 换能器界面特性评价等方面的研究取得了初步而重要的进展,具有重要应用前景;(4)在语音听觉系统特别是嗓音康复方面,研究了基于发声系统补偿调节机制的实时多模式嗓音源再生方法和发声生理,建立基于神经、肌肉和空气动力系统的综合补偿调节模型,提出了相应的评价系统。

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Do not gum up the work by telling mother what we are going to do .

别告诉母亲我们要干的事,那会把事情搞糟的。

In recent years, application of the partial prestressed concrete beam s is developed.

近年来,随着部分预应力砼梁应用的推广,发现我国规范所采用的名义拉应力法的计算结果不稳定。

Gorky once said:"If it is not a book, I'd be stupid and indecent drowning."

高尔基曾说:"如果不是书籍的话,我就要被愚蠢和下流淹死。"