使逆转

Treatment of cisplatin-resistant cell lines with an inhibitor of DNA methyltransferases, 2-deoxy-5'azacytidine, results in partial reversal of DNA methylation, re-expression of epigenetically silenced genes including hMLH1 and sensitisation to cisplatin both in vitro and in vivo.

DNA甲基转移酶抑制剂2 -脱氧- 5'氮胞苷可部分逆转顺铂耐药细胞株的DNA甲基化，在体外和体内使后生沉默基因包括hMLH1基因重新表达并增加对顺铂的敏感性。

Experts'research on the stability of water-based ink and process has been a preliminary study. Femandez and other matozoa of the discovery of water-based ink by electrostatic repulsion stability and space steric 's. Aromtics and gecol, and so on the surface of the plastic film studies indicate that water-based inks, join different types of surfactants can be effective removal of water-based inks, and Canadians zephiramine hexadecyl alkyltrimethylammonium can make the surface charge of carbon black particles.

国际学者差火性油墨的稳不退性和脱除工艺已举行了开端查究。femandez等发掘火性油墨的胶体稳不退性是由静电排不引力和不满答位阻效应成群不决的。gecol等差脱除塑料薄膜暗不天的火性油墨查究后暗示，参加差别种类暗不天活性剂均可灵验去除火性油墨，而且加人阳离子暗不天活性剂十六烷基不一甲基溴化铵可以使炭暗粒子暗不天电荷逆转。

"These people can potentially benefit themselves if we know to start them quickly and aggressively on antiretroviral treatment," Pilcher says.

Pilcher说道：「如果我们使他们开始快速而强大的抗逆转录病毒疗法，这些人可能获益匪浅。

Objective This study was designed to investigate the different status of provirus HIV DNA in non-progressor and progressor of HIV-1 infected persons.Methods HIV RNA, HIV DNA were detected with long-distance PCR,reverse-transcription PCR,Southern blot and molecular hybridization from plasma and peripheral blood mononuclear cells, using primers locating between long terminal repeats LTR(U5)-LTR and so on.

HIV是一种变异非常活跃的病毒，这种变异既有可能医疗增强病毒在宿主体内的适应性和生存，又有可能医疗使病毒复制受到阻碍，影响病毒在宿主体内的生存，为了更进一步掌握HIV变异规律，阐明HIV致病机理，我们用逆转录PCR、长片段PCR、Southern转印、分子杂交等对HIV感染无进展者和进展者HIV RNA、CD4细胞、HIV DNA及存在状态进行了研究。

Objective This study was designed to investigate the different status of provirus HIV DNA in non-progressor and progressor of HIV-1 infected persons.Methods HIV RNA, HIV DNA were detected with long-distance PCR,reverse-transcription PCR,Southern blot and molecular hybridization from plasma and peripheral blood mononuclear cells, using primers locating between long terminal repeats LTR(U5)-LTR and so on.

HIV是一种变异非常活跃的病毒，这种变异既有可能增强病毒在宿主体内的适应性和生存，又有可能使病毒复制受到阻碍，影响病毒在宿主体内的生存，为了更进一步掌握HIV变异规律，阐明HIV致病机理，我们用逆转录PCR、长片段PCR、Southern转印、分子杂交等对HIV感染无进展者和进展者HIV RNA、CD4细胞、HIV DNA及存在状态进行了研究。

We tested whether tetrahydrobiopterin (BH4) can recouple NOS and reverse preestablished advanced hypertrophy, fibrosis, and dysfunction.

我们检测四氢生物喋呤（BH4）是否能够使一氧化氮合酶恢复偶联并逆转心脏肥大、纤维化和功能障碍。

The thought process which underpins this new minimal invasive approach can be organized into three main categories:(1) Recognize, which means identify patient caries risk,(2) Remineralize, which means prevent caries and reverse non-cavitated caries, and (3) Repair, which means control caries activity, maximize healing and repair the damage.

微创牙科学的处理方法可概括为3个步骤：(1)判定患者的患龋风险；(2)再矿化，即防止龋损形成并逆转未形成&洞&的浅龋；(3)修复，即控制龋活性，使愈合潜能最大化并修复龋损。

Viral vector mainly contain adenovirus, retrovirus,adeno-associated virus and so on, but it has potential danger of safety; it isrepeled by immune system when it is injected to organism for a greatimmunogenicity. An injection with adenovirus vector with highconcentration, it leads to serious inflammatory reaction of liver. Viralvector such as liposome and polycation are commonly used lately. But,liposome and polycation have low specificness and targetness of genetransfer tissue, have lower transfection efficiency and short period ofgene expression, for they can be phagocytized by endothelial system.

许多的载体，病毒载体和非病毒载体以前已广泛应用，病毒载体主要包括腺病毒，逆转录病毒，腺相关病毒等；但病毒载体在安全性方面存在潜在的危险；免疫原性比较强，注射到机体后很快会被机体的免疫系统排斥，当静脉注射高浓度的腺病毒载体会使肝脏发生严重的炎症反应；非病毒载体目前常用的有脂质体及多聚阳离子聚合物；但脂质体和阳离子聚合物介导基因转移缺乏组织的特异性和靶向性，转染效率较低且易被网状内皮系统吞噬，基因表达时间短；因此研制新型的非病毒载体已成为研究的热点，纳米颗粒具有小尺寸效应，表面效应，随着颗粒直径变小，比表面积将会显著增大，故具有很高的化学活性，因而纳米成为了最有应用前景的非病毒载体。

The gravitation relation which the axis of rotation between moon and earth is out of the vertical has make the earth's crust move in sine curve and result in many mystery, such as reversion of magnetic field of the earth's crust, coal in South Pole, ice age of Africa, furthermore the continual earthquake which has occurred for more than 5,000,000 times on the earth.

月亮与地球自转轴不垂直的引力关系，使地壳弦动从而导致如地壳磁场逆转，南极有煤，非洲有冰川期等许多自然之谜的发生，更使得地球每年有500多万次大小地震的频繁发生。

A great fightback to win the tie and great support.

伟大的逆转使球队晋级四强并赢得巨大支持。

I smile at your play with that little bit of a broken twig.

我微笑着看你玩那一段小小的树枝。

They may be produced for almost any shaft angle.

他们可能在制作中几乎任何一个轴角。