查询词典 suppressor grid

The big difference between these two alternatie ways that tumour cells use to inactiate tumour suppressor genes is that, while the reersal of genetic alterations is technically almost unfeasible in clinical scenarios, the function of these epigenetically inactiated suppressor genes is easily reactiated by pharmacological means.

这两种改变方式最大的不同之处在于肿瘤细胞利用失活的肿瘤抑制基因，而在同时相反的遗传学改变在临床方案上是很难实施的技术。

The resulting strain, designated YES2MTM1, was transformed with a yeast genomic library. Transformants lost the plasmid overexpressing MTM1 after 5-FOA treatment. Yeast strains able to grow on nonfermentable carbon source with MTM1 deletion and overexpression of some DNA fragments were picked up and candidate suppressor genes were identified. Overexpression of five genes were identified to be able to rescue the growth defect on nonfermentable carbon source. The study will provide reference for MTM1 gene function and screening for suppressor of genes whose deletion result in irreversible damage.

为了避免MTM1缺失造成的不可逆损伤，在野生型酵母中先转入带有MTM1 基因的质粒，再敲除染色体上的MTM1 基因，随后转入基因组文库，再利用药物5-氟乳清酸(5-FOA)迫使细胞丢失表达MTM1基因的外源质粒，再筛选能在非发酵培养基上生长的转化子，通过这种方法筛选发现，POR2等5个基因的过表达可以挽救MTM1 基因缺失造成的非发酵培养基上的生长缺陷，为深入了解MTM1基因的功能提供了线索，对筛选其他造成不可逆损伤的突变基因的抑制基因提供了一条可行的研究思路。

To obtain more information of magnesium homeostasis in mitochondria, mTn-lacZ/LEU2 transposon library was transformed into mrs2 deletion mutant to screen for suppressor genes of MRS2. YMR166C, a member of mitochondrial carrier family, was identified as a suppressor gene of MRS2. Deletion of YMR166C gene can rescue the defects of mrs2 deletion mutant such as the decrease in mitochondrial magnesium concentration, Group II RNA splicing defect and growth defect on nonfermentable carbon source. For the first time we demonstrated YMR166C is involved in mitochondrial magnesium homeostasis.

为了增进对线粒体镁离子代谢调控基因的了解，利用酿酒酵母mTn-lacZ/LEU2转座子文库筛选MRS2的抑制基因，发现线粒体载体家族成员YMR166C基因的缺失可以挽救MRS2基因缺失的突变体的生长缺陷、II型内含子剪接缺陷，并可以调节线粒体镁离子浓度，首次发现YMR166C是线粒体镁代谢相关基因。

Suppressor is the key part for IC instrument, and developing a high performance suppressor for IC instrument is quite important to gradient ion chromatography, to analysis of some ions which have strong affinities with the functional groups located on the surface of the pellicular ion exchange column packing.

抑制柱是离子色谱仪的一个核心部件，研制具有较高抑制容量的抑制柱对于离子色谱法的梯度淋洗、对于在分离柱上保留时间长的离子分析具有重要的意义。

Part-3 Tumor Suppressor Gene PTEN Up-regulates p53 Level and Sensitizes Hepatocellular Carcinoma Cells to Chemotherapy Objective: To investigate the effects and the mechanisms of tumor suppressor gene PTEN on level of p53 protein and sensitivity of HepG〓 cells to chemotherapy.

第三部分 PTEN在肝癌细胞中上调p53蛋白水平并增强化疗药物敏感性目的：研究抑癌基因PTEN对肝癌细胞化疗药物敏感性及p53蛋白水平的影响，并探讨相关机制。

The basic idea is to set a continuous solution of the region with a finite number of discrete points instead of a grid consisting of, these discrete points called grid nodes the solution of a continuous area on a given function of continuous variables used in the definition of discrete grid variable function approximation the original equation and boundary conditions in the micro-business operators to approximate differential, integral with the points and to approximate, so the original differential equations and boundary conditions are replaced by algebraic equations near Side, that is, finite difference equations , solve this equation group can get the original problem in discrete points on the approximate solution.

基本思想是把连续的定解区域用有限个离散点构成的网格来代替，这些离散点称作网格的节点；把连续定解区域上的连续变量的函数用在网格上定义的离散变量函数来近似；把原方程和定解条件中的微商用差商来近似，积分用积分和来近似，于是原微分方程和定解条件就近似地代之以代数方程组，即有限差分方程组，解此方程组就可以得到原问题在离散点上的近似解。

P; displaylang = zh-cn writing paper download add-ons, installation Word2003 after the "Format" menu can be seen under the "writing paper set "command, select the Settings dialog box in the" Enable the following line of writing paper ", and then we set the size of each grid, grid style, grid color, paper size and so on, determined Word of the manuscript paper on the automatic application of styles, the text was on the manuscript paper on each lattice.

p；displaylang=zh-cn ）上下载稿纸加载项，安装后在 Word2003的"格式"菜单下就可以看到"稿纸设置"命令，选择后在设置对话框"启用稿纸隔线"，然后我们设定每格的尺寸、网格样式、网格颜色、纸张大小等，确定后 Word 中的就自动应用稿纸样式，文字被放到稿纸的每个格子上。

Semantic Web, semantic grid and semantic network are three confusable concepts. The semantic Web is an extension of WWW. Its goal is making computer understand and process the data on the Web and providing various intelligent services. Semantic grid is produced by semantic Web in combination with grid; semantic network is a diagrammatical notation of knowledge, it consists of nodes and arcs.

语义网、语义网格和语义网络是三个容易混淆的概念，语义网是对WWW的延伸，其目标是使得Web上的信息具有计算机可以理解的语义，并为人们提供各种智能服务；语义网格是语义Web和网格相结合产生的新的研究领域；语义网络是知识的一种图解表示，它由节点和弧线或链线组成。

On the base of fatigue loading spectrum achievements, combining the characteristics of large-span grid structure with hanging cranes and the using-requirement on fatigue loading spectrum of grid structure with hanging cranes, this paper has firstly put forward the theoretic method for constructing fatigue loading spectrum of grid structure with hanging cranes, organized the relevantprogram--GJFLS. and elementally established the program loadingspectrum .

在继承疲劳载荷谱已有成果的基础上，本文结合网架设置悬挂吊车的特点以及网架疲劳载荷谱的使用要求，首次提出了网架疲劳载荷谱编制的理论方法，并编制了相应的程序，初步建立了网架程序载荷谱。

This paper disserts the represent form of space data model, and discusses three dimensional space data model based on the grid, and points out the integrated necessariness and integrated represent method about the grid-vector spatial data model, and provids a Euclidean distance converting model and algorithm with regard to change from vector data to grid data, as well as establishes the foundation for spatial data handing and spatial data mining.

文章论述了空间数据模型的表示形式，重点讨论了基于栅格的三维空间数据模型，指出了栅格矢量空间数据模型集成化的必要性以及集成化表示方法，给出了将矢量数据转换为栅格数据的欧氏距离变换与算法，为基于栅格空间数据的空间数据处理和空间数据挖掘奠定了基础。

Cable dampener cannot be rolled up but must be hung over the cable.

缆帆不能被卷起，必须保证处于展开状态

"This skylark is a present from my master," he says.

"这只云雀是我主人献上的礼物。"他说。