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Ping chuan-fang prescription is carefully composed accordingly. The clinical investigation shows that PCHF can not only alleviate symptoms and physical sign of the patients effectively, but also shorten the course of disease and obviously can not only alleviate symptoms and physical sign of the patients effectively, but also shorten the course of disease and obviously improve the pulmonary function of the patient. The animal experiment showed that PCHF can prolong the asthmatic time and low the concentration of WBC, EOS, IL-4, ET-1 in the blood and BALF. It can restrain the collection of EOS in the lung and relieve the inflammation caused by EOS. It also can cut down the secretion of the respiratory air-way and relieve the obstruction of it.

动物实验表明:平喘方能明显延长卵蛋白造模大鼠的引喘潜伏期,且与氨茶碱对照有非常显著性差异(P<0.01);能降低哮喘模型大鼠血浆及肺泡灌洗液中白细胞、嗜酸性粒细胞及IL-4、ET-1的含量;能抑制肺局部EOS的聚集,明显减轻由EOS浸润引起的慢性变应性炎症反应;能减少气道分泌物,减轻细支气管及小血管管壁的增厚,减轻周围组织的水肿,从而减轻气道的阻塞,最终改善肺通气,缓解喘息症状。

Ping chuan-fang prescription is carefully composed accordingly. The clinical investigation shows that PCHF can not only alleviate symptoms and physical sign of the patients effectively, but also shorten the course of disease and obviouslycan not only alleviate symptoms and physical sign of the patients effectively, but also shorten the course of disease and obviously improve the pulmonary function of the patient. The animal experiment showed that PCHF can prolong the asthmatic time and low the concentration of WBC, EOS, IL-4, ET-1 in the blood and BALF. It can restrain the collection of EOS in the lung and relieve the inflammation caused by EOS. It also can cut down the secretion of the respiratory air-way and relieve the obstruction of it.

动物实验表明:平喘方能明显延长卵蛋白造模大鼠的引喘潜伏期,且与氨茶碱对照有非常显著性差异(P<0.01);能降低哮喘模型大鼠血浆及肺泡灌洗液中白细胞、嗜酸性粒细胞及IL-4、ET-1的含量;能抑制肺局部EOS的聚集,明显减轻由EOS浸润引起的慢性变应性炎症反应;能减少气道分泌物,减轻细支气管及小血管管壁的增厚,减轻周围组织的水肿,从而减轻气道的阻塞,最终改善肺通气,缓解喘息症状。

Rabbit anti-thrombosis in oral fungus polysaccharides 18.5mg/kg, can significantly extend the specificity of thrombus and fibrin thrombus formation time and shorten the length of thrombus, reduce the thrombus wet weight and dry weight, reduce platelet count, lower platelet adhesion rate and blood viscosity, and can significantly shorten the guinea pig euglobulin lysis time, lower plasma fibrinogen levels, elevated plasmin activity, results showed that the fungus polysaccharides significantly antithrombotic effect.

抗血栓形成兔口服木耳多糖18.5mg/kg,可明显延长特异性血栓及纤维蛋白血栓的形成时间,缩短血栓长度,减轻血栓湿重和干重,减少血小板数,降低血小板粘附率和血液粘度,并可明显缩短豚鼠优球蛋白溶解时间,降低血浆纤维蛋白原含量,升高纤溶酶活性,结果表明,木耳多糖有明显的抗血栓作用。

Rabbit anti-thrombosis in oral fungus polysaccharides 18.5mg/kg, can significantly extend the specificity of thrombus and fibrin thrombus formation time and shorten the length of thrombus, reduce the thrombus wet weight and dry weight, reduce platelet count, lower platelet adhesion rateand blood viscosity, and can significantly shorten the guinea pig euglobulin lysis time, lower plasma fibrinogen levels, elevated plasmin activity, results showed that the fungus polysaccharides significantly antithrombotic effect.

抗血栓形成兔口服木耳多糖18.5mg/kg,可明显延长特异性血栓及纤维蛋白血栓的形成时间,缩短血栓长度,减轻血栓湿重和干重,减少血小板数,降低血小板粘附率和血液粘度,并可明显缩短豚鼠优球蛋白溶解时间,降低血浆纤维蛋白原含量,升高纤溶酶活性,结果表明,木耳多糖有明显的抗血栓作用。

The result indicated that HSC could obviously cut down the occurrence of rentricular vibration induced by chloroform in mice,lengthen the time of arrhythmia appearance,shorten the time of arrhythmia continuum and conversion induced by barium chloride in model rats,it also could shorten the time of ventriclar extrasystole and ventricular tachycardia in model rats induced by aconitine.

结果表明:黄松胶囊能明显降低氯仿所诱发小鼠室颤的发生,明显延长氯化钡模型大鼠心律失常出现时间,缩短模型大鼠心律失常持续和复律时间,尚能明显缩短乌头碱性大鼠心律失常的室性早搏及室性心动过速持续时间,与模型对照组比较均有统计学差异。

Group C: shorten for 1cm and fixation by unilateral lengthener. 500ul platelet-rich plasma are locally injected into distraction gap in day 17 and 27 post-operation. Group D (DBM+PRP group): fill the bone defect with 0.5cm decalcified bone matrix and 1ml platelet-rich plasma and shorten 0.5cm.

在术后第17天和术后第27天局部注射富血小板血浆500ul两次。D组:将0.5cm长的脱钙骨基质材料复合1ml富血小板血浆填入1cm的骨缺损并短缩0.5cm后外固定架固定。

All the animals will be terminated at day 37 following initial surgery. 3. Experimental groups: Group A: shorten for 1cm and fixation by unilateral lengthener. Group B: fill the bone defect with 0.5cm decalcified bone matrix and shorten for 0.5cm.

实验分组:A组:胫骨短缩1cm后外固定架固定。B组:将0.5cm长的脱钙骨基质材料填入骨缺损并短缩0.5cm后外固定架固定。C组:胫骨短缩1cm后外固定架固定。

Hemostatic mechanism total saponins of Yinfenglun were studied on plasma recalcified time, FT, KFTT and ELT. Result: TSY at different doses could markedly shorten bleeding time, reduce bleeding volume in mice. TSY also could shorten clotting time of mouse, rat and dog. TSY could influence both intrinsic coagulatian system and extrinsic coagulatian system, and had no effect of antifibrinolysis.

结果:荫风轮总苷不同剂量可明显缩短小鼠断尾出血时间,减少出血量,并能缩短小鼠、大鼠、犬凝血时间;可明显缩短家兔血浆复钙时间、凝血酶原时间和白陶土部分凝血活酶时间,但对大鼠优球蛋白溶解时间无明显影响,表明荫风轮总苷既能影响内源性凝血系统,又能影响外源性凝血系统。

Result] Nvjin capsule can markedly improve mouse pain tolerance, inhibit ear swelling, shorten cuttail blooding time and obviously shorten TT and Fbg, but has little influence on PT;can markedly raise platelet collection rate.

结果]女金胶囊可明显提高热板法致痛的小鼠痛阈;对二甲苯所致小鼠耳廓肿胀有明显的抑制作用,还能显著缩短小鼠断尾出血时间;显著缩短TT和减少Fbg水平,而对PT影响较小;显著升高血小板聚集率。

In Wistar rats, latent period of a-wave in scotopic rod response after 1-week transplantation was shorten (P.05); and latent period of a-wave in scotopic rod response after 2-week transplantation was prolonged (P.05); while latent period of b-wave in scotopic maximum response after 1-week transplantation was shorten (P.05). In RCS rats, amplitude of a-wave in scotopic rod response and photopic response after 4-week transplantation was increased (PO.05); while latent period of a-wave in scotopic rod response after 4-week transplantation was shorten (PO.05).Conclusion 1. At the age of 3 months, photoreceptors of the RCS rat degenerated completely, which leaded to the reduction of amplitudes of a-wave and b-wave.

Wstar大鼠术后1周的暗适应视杆反应,a波潜伏期缩短o叼。05);术后2周的暗适应视杆反应,a波潜伏期延长o功刀5):术后1周的暗适应最大反应,b波潜伏期缩短o功刀5卜*CS大鼠术后4周的暗适应视杆反应和明适应反应,a波振幅增大o功刀匀;术后4周的暗适应视杆反应,a波潜伏期缩短o<0卜结论1、RCS大鼠在3月龄时感光细胞变性死亡,导致FERG的a、b波振幅明显降低;视网膜下腔仍存在感光细胞外节盘膜碎屑,外丛状层缺乏感光细胞的突触末端,同时Muler细胞出现反应性胶质纤维增生。

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