查询词典 proliferating

Two cases of specimens collected in operation were studied by in situ RT????PCR, of which 50 cases were hemangioma: 26 cases proliferating hemangioma and 24 cases involuting hemangioma, and 12 cases were venous vascular malformation. The expression of Ang2 mRNA and Tie2 mRNA in hemangiomas and venous vascular malformation were detected by in situ RT????

PCR方法，对临床收集的62例手术切除的先天性皮肤血管标本（其中增生期血管瘤26例，消退期血管瘤24例，静脉型血管畸形12例）进行Ang2 mRNA， Tie2 mRNA表达水平的检测。

Results: The positive expression rates of Matrix MetallProtinase-2 protein in the cases of proliferating groups, involuting group , vascular malformation group and normal skin group were respectively 32%、12%、8%、5%.

结果 在血管瘤增生期、血管瘤退化期、血管畸形、正常皮肤组织中MMP-2表达的阳性率分别为32%、12%、8%、5%，血管瘤增生期组明显高于其它3组(P.05)；其差别具有显著性意义。

Its difference was significant. The positive expression rates of Tissue Inhibitors of Metalloproteinase-2 protein in the cases of proliferating group, involuting group , vascular malformation group and normal skin group involuting group were respectively10%、28%、6%、5%.

其差别具有显著性意义 1、增生期血管瘤组织中，MMP-2表达明显升高，可以认为MMP-2通过降解血管基膜和细胞外基质促进小儿血管瘤血管形成，从而促进血管瘤增殖。

The positive expression rates of Tissue Inhibitors of Metalloproteinase-2 protein in the cases of involuting groups were significantly higher than those in proliferating group and vascular malformation groups and normal skin group (P.05). Its difference was significant. Conclusions: Matrix MetallProtinase-2 and Tissue Inhibitors of Metalloproteinase-2 may play an important role in the pathogenesis of hemangiomas through angiogenesis. They may have no effect on vascular malformation and normal skin

血管瘤退化期，TIMP-2表达明显升高，说明 TIMP-2与血管瘤纤维化、消退有关，其机制可能是一方面通过抑制MMP-2介导的基底膜降解而在内皮细胞迁移、聚集中起作用，另一方面直接抑制内皮细胞的增殖及迁移，使内皮细胞高频率调亡，细胞外基质增多，组织出现纤维化，最终导致血管瘤的退化。2、血管畸形和正常皮肤小血管中MMP-2和TIMP-2不表达或表达较弱，说明血管畸形和正常皮肤小血管中并不存在异常的血管生成，据此可以对血管性疾病进行分型、分期，并指导临床治疗。

Results: In hemangioma at proliferating phase, hemangioma at involuting phase, and normal skin, the expressions of TRAIL were 1.26±0.56, l.74±0.68, and 1.00±0.23, PI was (40.98±12.02)%,(20.05±3.67)% and (15.64±4.01)%, AR was (11.96±4.02)%,(20.29±3.53)% and (6.61±1.29)%, respectively. There were significant differences among the 3 groups in the 3 parameters.

结果：增生期血管瘤、消退期血管瘤和正常皮肤组织中TRAIL蛋白的表达分别为1.26±0.56，1.74±0.68，l.00±0.23，PI分别为(40.98±12.02)%，(20.05±3.67)%，(15.64±4.01)%，AR分别为(11.96±402)%，(20.29±3.53)%，(6.61±1.29)%。3组间以上3指标两两比较，差异均有统计学意义。

objective:to investigate the expression and significance of rb in the occurrence, development and regression of infantile hemangiomas.methods:the expression of rb was examined in the proliferative stage and catagen of human hemangiomas and normal skin tissues by using immunohistochemical technique.immunohistochemical technique for factorⅷ-related antigen was used to prove that the cells which expressed rb were endothelium.image analysis system was applied to measure the expression level of rb at different stages of hemangiomas and in normal skin tissues.results:the expression of rb was significantly lower in proliferating hemangiomas than that in involuting hemangomas(p.05).conclusion:rb might play an important role in the regression of human hemangioma endothelial cells and anti-angiogenesis.

目的：探讨rb蛋白在血管瘤发生、发展及退化过程中的表达状况及其意义。方法：采用免疫组织化学方法检测人皮肤血管瘤增生期、退化期及正常皮肤组织中rb的表达水平，并结合第ⅷ因子相关抗原的免疫组织化学染色证实表达rb的细胞是血管内皮细胞。利用计算机图像分析技术测量不同时期血管瘤组织和正常皮肤组织rb表达的积分光密度和面积。结果：增生期血管瘤内皮细胞rb表达水平低于退化期，差异有显著性（p.05），退化期血管瘤内皮细胞rb表达水平与正常皮肤组织相比，差异有显著性（p.05）。结论：rb通过抑制血管瘤内皮细胞增殖和血管生成而在血管瘤的退化过程中起重要作用。

Methods: The expression of P57(superscript kip2) was examined in proliferating, involuting human hemangiomas and normal skin tissues by using immunohisto-chemical technique. Immunohistochemical technique for factor Ⅷ-related antigen was used to identify that the cells which expressed P57(superscript kip2) were endothelia.

采用免疫组织化学方法检测人皮肤血管瘤增生期、退化期及正常皮肤组织中P57(上标 kip2)的表达水平，并结合第Ⅷ因子相关抗原的免疫组织化学染色证实表达P57(上标 kip2)的细胞是血管内皮细胞。

Objective To investigate the expression of vascular endothelial growth factor and proliferating cell nuclear antigen in keloids and hypertrophic scars.

目的 探讨瘢痕疙瘩和增殖性瘢痕等异常疤痕中血管内皮生长因子和增殖细胞核抗原的表达及其意义。

Objective To investigate theexpression of vascular endothelial growth factor and proliferating cell nuclearantigen in keloids and hypertrophic scars.

目的 探讨瘢痕疙瘩和增殖性瘢痕等异常疤痕中血管内皮生长因子和增殖细胞核抗原的表达及其意义。

This study was conducted to examiune the fibrotic effect of Ni-Ti and 317L al loys in esophagus.The extract fluid from Ni-Ti,317L alloys was made according t o the ASTM standards of U.S.A. The Fb of esophageal scar was cultured primarily ,then incubated with alloy abstract fluid. The proliferating activity of Fb was measured by MTT at 4, 24, 48, 72 hours in the course of culturing. The esophagu s embedding test of Ni-Ti,317L alloys was made according to ASTM standards of U .S.A.The tissue around the alloys was taken at weeks 2 and 12,and the pathologi c changes were analysed.

为探讨新型支架材料Ni-Ti、317L合金在食管局部的致纤维化作用，按美国ASTM标准制备NiTi、317L合金的金属浸提液；&组织块培养法&原代培养食管壁疤痕的成纤维细胞，传代后以金属浸提液进行培养，分组后分别培养4、24、48、72 h，MTT法检测不同培养时间后Fb增殖功能的变化；按美国ASTM标准进行NiTi、317L合金试件的食管壁内包埋实验，即将金属试件经表面处理后直接置入食管壁粘膜层与肌层之间，术后2、12周取出包埋组织，分析试件周围组织的病理变化，并进行胶原纤维染色，观察纤维形成状况。

Anna: No, I've got a hangover.

不是，我昨晚宿醉了。

We head into the mountains in Su's new Land Cruiser, stop for lunch at a scenic restaurant and then hang around drinking beer and eating fruit as two of his employees attempt to lure the birds with a tape recording of the fowl's mating call.

我们坐上苏的巡逻车向山顶出发，在一家风景优美的餐馆吃了中饭。然后我们喝着啤酒吃着水果四处逛。