查询词典 profiling

To investigate the function of Nogo-A in neurons, human embryonic kidney cell line 293FT was used as a model, along with the pathway profiling reporter system to check the involvement of Nogo-A in regulating the intracellular signaling pathway. It was found that over-expression of Nogo-A could activate NF-KB signaling specifically, then followed by using different Nogo-A alternative splicing isoforms and a serial of truncations, it was confirmed that the activation of NF-kB by Nogo-A relied on its N-terminal proline rich domain. Furthermore, by co-expressing the dominant negative mutants of some NF-kB pathway associated proteins, it revealed that the IkBα,TRAF6, Rac/Cdc42 were involved in Nogo-A inducing activation of NF-kB.

为探讨神经元内Nogo-A的功能，以HEK293FT细胞为模型，利用信号途径报告基因系统筛选过表达Nogo-A对多种信号途径的调控作用，发现过表达Nogo-A能特异激活NF-kB信号，利用不同的Nogo-A剪接体和截断体形式研究，证明Nogo-A激活NF-kB信号依赖于其氨基端的proline rich结构域，进一步使用NF-KB信号途径相关分子显性突变体揭示IkBα、TRAF6、Rac/Cdc42参与Nogo-A激活NF-kB信号。

The LIR and LV models can be used in conjunction with the spinning mirror assembly and high speed interface card to make a laser line scanne r for profiling scenes and objects.

AR4000的LV和LIR型号还可以联合组装旋转镜和高速接口卡做成在线激光传感器来分析场景和对象。

If you are unfortunate enough to the lovelorn, please tell me, I will help you out, really, please contact me!

如果你不幸失恋了，请告诉我，我会帮助你摆脱困境，真的，请联系我啦！

China's plan to cut energy intensity by 20 percent and pollutant discharges by 10 percent between 2006 and 2010 is a case in point.

中国计划在2006年到2010间降低20%的能源强度和减少10%的主要污染物排放，就是一个这样的例子。