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The typical manifestations of PHC were nodular,irregular and heterogenous enhanced regions in lesion,tumorous vessels could be seen in the arterial phase,the hyperdense regions in the arterial phases were changed to hpodense quickly in the portal phase;The characteristic findings of HCH were well-defined intense mural nodular enhancement in the arterial phase,and centripetally oriented enlargement of this nodular in the portal phase,the density of the nodular in the arterial phase were similar to that of aorta or hepatic arteries.

原发肝癌的典型表现是动脉期病灶内结节状、片状强化,并可见肿瘤血管影,强化部分在静脉期迅速呈低密度影;肝血管瘤的特征性表现为动脉期病灶边缘结节状强化,密度类似于主动脉或肝动脉,静脉期强化结节逐渐向病灶中央扩展;肝转移癌的主要表现为动、静脉期病灶边缘环状强化,中央部分无明显强化,静脉期还可见到"牛眼征"。

Abstract] objective to study the pathological features and histopathological type and differential diagnosis of hepatic focal nodular hyperplasia.methods the clinicopathological characteristics of 40 cases of fnh were studied.all were evaluted by use of paraffin embedded sections and he staining before light microcope observation.results there were 28 females and 12 males fnh patients whose age were from 16 to 62 years(median 41.3),all alpha-fetoprotein was negative and had no hepatitis history.25 cases were classic type showed characteristic central stellate fibrotic scar,composed of fibrous connestive tissue and tortuous blood vessels.8 cases were telangiectic type,the left were mixed type and adenomatoid type.conclusion fnh is a reactive proliferation of hepatic cells to local blood vessel anomalies,it is not realy a tumor.its differential diagnosis includes hepatic adenomatous hyperplasia nodule,hepatic anaplasia nodular hyperplasia,fibrolamellar hepatocellular carcinoma and hepatocellular adenoma.

目的 探讨肝局灶性结节性增生的病理形态特点、组织分型及鉴别诊断。方法分析40例肝局灶性结节性增生的临床资料,并采用石蜡包埋he染色光镜下观察其组织学特点。结果 40例肝局灶性结节性增生患者中,女28例,男12例,年龄18~62岁,平均年龄41.3岁,所有病例术前均无肝炎病史,甲胎蛋白阴性,组织学上25例为经典型,有特征性的中央纤维瘢痕,由纤维结缔组织及扭曲血管组成。8例为毛细血管扩张型,其余为混合型及腺瘤样增生型。结论肝结节性增生是一种肝细胞对局部血管的异常反应性增生,并非真性肿瘤,主要与肝腺瘤样增生性结节、肝间变性结节状增生、肝纤维板层癌及肝细胞腺瘤鉴别。

Results:① 37 cases shown ascites (59.7%). 14 cases shown showed little;②19 cases shown thicken-peritoneum (30.6%), 8 cases nodular shadows; 5 cases shown cingulum shadows; 6 cases shown mass shadows;③ 17 cases changed epiploon (27.4%), 5 cases showed smudged, 3 cases nodular shadows; 9 cases caked sign;④ 4 cases cystoid mass (6.4%) in ovarian neoplasm;⑤ 2 cases deviated intestine with thickened bowel wall (3.2%).

结果:①腹水37例,占59.7%,其中少量腹水14例,大量及中等量腹水23例;②腹膜增厚19例,占30.6%,其中结节状8例、条带状5例、块状增厚6例;③网膜改变17例,占27.4%,污垢状5例、结节状3例、饼状9例;④腹腔内囊性占位性病变共4例,占6.4%,均见于卵巢癌;⑤小肠壁增厚伴肠管移位2例,占3.2%。

Two cases were classified as diffuse lymphoblastic lymphosarcoma and one each as nodular prolymphocytic, nodular lymphoblastic, diffuse mixed cell type lymphosarcoma, Lennert's lymphoma, mixed cell type Hodgkin's disease.

按组织学分型,弥漫性淋巴母细胞型2例和弥漫性混合细胞型淋巴肉瘤、结节性前淋巴细胞型、结节性淋巴母细胞型、Lennert氏淋巴瘤及混合细胞型何杰金氏病各1例。

nodular dermal vasculitis in lower extremities are often seen clinically in middle-age women, and are evoked by many causes. Some laboratory examinations have abnormal outcomes and we think these are related with autoimmune reactions of nodular dermal vasculitis. We can make diagnosis with clinical character of erythema and nodose lesions in lower extremities, laboratory examinations and histopathology inspection. Antibiotics, non- Steroid anti-inflammatory drugs, anti-tubercle drugs and corticosteroids are effective drugs.

结节型皮肤血管炎多发于中年女性;结节型皮肤血管炎病因复杂,可能是由于细菌、真菌、病毒、结核、药物等所引起,也可为某些全身性疾病的皮肤表现;实验室指标异常改变可能与疾病免疫反应有关;结节型皮肤血管炎诊断以双下肢红斑结节性损害的临床特点,结合实验室及组织病理学检查可确诊分型;结节型皮肤血管炎针对病因选用抗生素、非甾体抗炎药、抗结核药、皮质类固醇激素等治疗有效。

When the pouring temperature is close to the liquidus temperature of AlSi7Mgalloy, the primary α-Alin the billets of AlSi7Mg alloy solidifies into spherical or nodular grainswhich are small and distributed homogeneously. In order to obtain non-dendritic semi-solidbillets,the appropriate pouring temperature is 615℃. The faster cooling rate,the melt flowing and largersolidification region induced by the near liquidus pouring temperature promotes theformation of spherical or nodular primary α-Al.

实验表明:当浇注温度接近液相线温度时,AlSi7Mg合金中的初生α-Al凝固成球状或粒状,晶粒细小,分布均匀;获得球状或粒状AlSi7Mg合金半固态坯料的最佳浇注温度为615℃;在接近液相线温度下浇注,较快的合金熔体冷却速度、浇注引起的合金熔体活动和大范围的同时凝固促使AlSi7Mg合金形成球状或粒状的初生α-Al组织。

The inflammation reaction hyperplactic stage and lymphatic nodular stage are of nonspecific morphological changes and should be diagnosed with the help of positive tuberculin test and obvious increase of adenosine deaninase ; tuberculous nodular stage has a great number of epithelioid cells,and Langhans cells, caseous necrosis stage is characterized by a great deal of necrotic tissue and debris,a small number of fragmented epithelioid cells, and mainly by antiacid bacteria fibrinous hyperplastic stage is featured by a few fibrous tissue, cells and mucous oweing to hardness to get puncture, which neans tuberculous restoration,and scar formation.

炎性增殖反应期非特异性形态学变化,需要结合结核抗体阳性和腺苷酸脱氨酶明显增高有助于诊断,结核结节期主要可有较多类上皮样细胞及郎罕氏细胞;而干酪样脓样坏死主要见大量坏死组织及碎屑、少数残碎不全类上皮样细胞,此期主要能查到抗酸菌为特征;纤维增殖期,抽出物难取,仅见少数纤维组织、纤维细胞和黏液间质为其特征,提示结核恢复、瘢痕形成所致。

The inflammation reaction hyperplactic stage and lymphatic nodular stage are of nonspecific morphological changes and should be diagnosed with the help of positive tuberculin test and obvious increase of adenosine deaninase ; tuberculous nodular stage has a great number of epithelioid cells,and Langhans cells,caseous necrosis stage is characterized by a great deal of necrotic tissue and debris,a small number of fragmented epithelioid cells,and mainly by antiacid bacteria fibrinous hyperplastic stage is featured by a few fibrous tissue,cells and mucous oweing to hardness to get puncture,which neans tuberculous restoration,and scar formation.

炎性增殖反应期非特异性形态学变化,需要结合结核抗体阳性和腺苷酸脱氨酶明显增高有助于诊断,结核结节期主要可有较类上皮样细胞及郎罕氏细胞;而干酪样脓样坏死主要见量坏死组织及碎屑、少残碎不全类上皮样细胞,此期主要能查到抗酸菌特点;纤维增殖期,抽出物难取,仅见少数纤维组织、纤维细胞和黏液间质为其特征,提示结核恢复、瘢痕形成所致。

The inflammation reaction hyperplactic stage and lymphatic nodular stage are of nonspecific morphological changes and should be diagnosed with the help of positive tuberculin test and obvious increase of adenosine deaninase ; tuberculous nodular stage has a great number of epithelioid cells,and Langhans cells, caseous necrosis stage is characterized by a great deal of necrotic tissue and debris,a small number of fragmented epithelioid cells, and mainly by antiacid bacteria fibrinous hyperplastic stage is featured by a few fibrous tissue, cells and mucous oweing to hardness to get puncture, which neans tuberculous restoration,and scar formation.

炎性增殖反应期非特异性形态学变化,需要结合结核抗体阳性和腺苷酸脱氨酶明显增高有助于诊断,结核结节期主要可有较多类上皮样细胞及郎罕氏细胞;而干酪样脓样坏死主要见大量坏死组织及碎屑、少数残碎不全类上皮样细胞,此期主要能查到抗酸菌为特点;纤维增殖期,抽出物难取,仅见少数纤维组织、纤维细胞和黏液间质为其特征,提示结核恢复、瘢痕形成所致。

The inflammation reaction hyperplactic stage and lymphatic nodular stage are of nonspecific morphological changes and should be diagnosed with the help of positive tuberculin test and obvious increase of adenosine deaninase ; tuberculous nodular stage has a great number of epithelioid cells,and Langhans cells, caseous necrosis stage is characterized by a great deal of necrotic tissue and debris,a small number of fragmented epithelioid cells, and mainly by antiacid bacteria fibrinous hyperplastic stage is featured by a few fibrous tissue, cells and mucous oweing to hardness to get puncture, neans tuberculous restoration,and scar formation.

结核初期-炎性增殖期60例,占5.5%;结核早期-淋巴结节期130例,占11.9%;结核中期-结核性结节期有590例,占54.1%;结核晚期-干酪样脓样坏死期有280例,占25.7%;结核恢复期-纤维素增殖期30例,占2.8%。炎性增殖反应期非特异性形态学变化,需要结合结核抗体阳性和腺苷酸脱氨酶明显增高有助于诊断,结核结节期主要可有较多类上皮样细胞及郎罕氏细胞;而干酪样脓样坏死主要见大量坏死组织及碎屑、少数残碎不全类上皮样细胞,此期主要能查到抗酸菌为特点;纤维增殖期,抽出物难取,仅见少数纤维组织、纤维细胞和黏液间质为其特征,提示结核恢复、瘢痕形成所致。

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