查询词典 lancelet amphioxus

Moreover,it was demonstrated that the threesubstances,E,DE and DA,increased dramatically and quickly after LPS treatment.Also,it was revealed that the changes of three substances were more quickly than thechanges of the above mentioned APPs during the same LPS treatment.Thesesuggested that the three substances existed as neurotransmitter.The presence and thechange of the CAs in amphioxus after treated with LPS indicated the evolutionaryexistence of CAs and acute phase response in the protochordate lineage.

第四，我们用高效液相色谱法(High Performance Liquid Chromatography，HPLC)，探讨了LPS感染文昌鱼儿茶酚胺类神经递质的变化，优化了同时测定文昌鱼体液中NE、E和DA三种CAs的HPLC方法，并首次发现，文昌鱼体液中同时存在NE、E、和DA三种CAs物质，其中，E在文昌鱼中首次报道，这三种物质在LPS感染文昌鱼后浓度升高非常明显，与同期的APPs相比变化更为迅速，也体现了神经递质的主导作用，文昌鱼的CAs系统也具有了类似脊椎动物CAs系统的功能，可以初步判断CAs系统的进化源头由脊椎动物可推回到头索类。

In this study, the genomic structure and regulatory elements of ApoD from 10 representive species including protozoan, invertebrate, protochordate and vertebrate were analyzed and compared. The genomic structure of ApoD is less conserved in organisms from protostome to deuterostome invertebrates, while it is highly conserved among chordates including amphioxus and verebrates. All four conserved cysteine residues are present in amino acid sequence of deuterostome ApoDs, while there are only two cysteine residues in amino acid sequence of protostomes ApoD. Structure divergence between protostome and deuterostome ApoD proteins suggests their function difference. The majority of regulatory elements are present in nearly all organism ApoD genes ranging from unicellular protozoan to mammals, suggesting that ApoD plays a very fundamental role, and possesses a conserved regulatory mechanism. However, there also exist some specific regulatory elements, which are present only in certain species and may perform some special roles.ApoD mRNA expression in murine NIH/3T3 fibroblasts exposed to various stresses such as as hydrogen peroxide and UV light shows dose-dependent increase. And a fly homolog of ApoD, Glial Lazarillo, whose overexpression results in increased resistance to hyperoxia as well as a extension of lifespan under normoxia and resistance to starvation without altering lipid or protein content.

本文首先从生物信息学角度对分属于原生动物、无脊椎动物、头索动物和脊椎动物类群的10种动物ApoD的基因结构及调控区的调控元件进行分析及比较，发现：(1)ApoD基因外显子-内含子结构从原生动物草履虫到原口动物再到后口动物海胆的进化过程中不保守，但在分析的几种脊椎动物中相当保守；(2)文昌鱼ApoD基因扮演从无脊椎动物到脊椎动物承上启下的角色，可能代表了脊椎动物ApoD基因原型；(3)四个半胱氨酸保守位点在后口动物中都存在，而在原口动物中只存在两个，原口、后口动物ApoD蛋白一级结构上的差异反映蛋白功能上可能也存在一定差别；(4)调控区大多数主要调控元件为不同动物共有，说明ApoD主要功能及其表达调控在进化中相当保守；(5)ApoD基因个别调控元件是随着物种进化而出现并开始发挥相关作用，如SF-1；还有一些调控元件在进化过程中还没有发现其规律，这说明ApoD某些功能和基因表达调控模式可能因物种不同而存在一定的差异。

Immunocytochemical localization were investigated for the first time in the gonads, brain vesicle and nerve tube of Amphioxus using polyclonal antibodies against 17 b -estradiol, testosterone and progesterone receptors.

首次用雌二醇、睾酮和孕酮受体的多克隆抗体在文昌鱼性腺、脑泡和神经管中进行免疫细胞化学定位研究。

On the other hand, we found for the first time that mammalian neurosteroids-like immunopositive nerve cell and its fiber existed in the brain vesicle and nerve tube of Amphioxus, and the positive substance distributed in the cytoplasm of nerve cell, while nucleus showed negative reaction.

本文研究还首次发现，文昌鱼脑泡和神经管中存在哺乳动物神经甾体激素样免疫阳性神经细胞及其纤维，免疫阳性物分布在神经细胞胞质，核显阴性反应。

The 277539 amphioxus ESTs were clustered to 15778 clusters,ssembled to roughly 19875 contigs and 18414 singlets,of which approximately 81.9%have a high confidence match to UniProt.

数据库提供了非常友好的用户界面，该库的建立为文昌鱼的比较基因组和功能基因组学研究提供了坚实的基础。

Using immunocytochemistry and in situ hybridization, we studied definitive tissue specific localization of aromatase in the nervous system, wheel organ, Hatschek's pit and gonads at young and adult female and male amphioxus at different stages of gonadal development.

本文用免疫细胞化学和原位杂交技术，首次发现芳香化酶活性组织特异性定位在幼年和性腺发育不同时期雌、雄文昌鱼神经系统、轮器、哈氏窝和性腺中。

Animal taxonomists described as a "living fossil" of the amphioxus, in the shallow water near the 15 m isobath density of 1035 / m, think about with these "living fossils" with swimming in a region, which can not but make you feel shock.

被动物分类学家誉为&活化石&的文昌鱼，在浅海15米等深线附近密度达到1035尾／平方米，想想能够与这些&活化石&同在一个区域游泳，这不能不使你感到震撼。

As a dominant party,CPC government should play a guardian,supervisee and guarantee role to overcome all the difficulties in the development of charitable cause and bring it into full play in the establishment of harmonious society on policies and regulations basis.

在中国共产党的文献中第一次把发展慈善事业提到&最广泛最充分地调动一切积极因素，不断提高构建社会主义和谐社会的能力&的高度来认识。近年来，社会学界对慈善事业的理论专著发表较多，有鉴于此，笔者不揣浅陋，谈谈自己的认识和见解。

Flow through the land, the land of the scale of operation allows the effectiveness of the land may be raised.

通过土地的流转，土地的规模经营可以让土地的效益得到提升。