查询词典 genomics

The research region focus on the genomic sequencing, disease genomics, functional genomics, bioinformatics.

其主要研究领域是基因组测序，疾病基因组，功能基因组和生物信息学。

During the postgenomics era the information about genomic sequence and gene functions provides a new foundation for evolutionary biology and ecology As the first whole-genome sequenced plant Arabidopsis thaliana and its wild relatives have played a critical role in understanding the evolution of genomics and speciation Both A halleri and A lyrata are closely related to the model species A thaliana A halleri ssp gemmifera occurs in northeastern China Japan and Taiwan; while its sister A halleri ssp halleri is mainly distributed in Europe Geographical barriers such as Tienshan Mountain Range isolate these intraspecific sisters Likewise A lyrata ssp kamchatica and ssp lyrata occur in East Asia and North America respectively Such distribution patterns seem to be consistent with allopartic speciation The comparison between ancestral and extant polymorphism by multilocus can be informative about the population genetics of speciation In this study we collected and analyzed DNA sequences of 98 genes from four wild relatives of A thaliana A halleri ssp gemmifera A halleri ssp halleri A lyrata ssp kamchatica and A lyrata ssp lyrata The ancestral states of these four species were compared to each other in terms of level of genetic variation However the ancestral species at the time of speciation were substantially more polymorphic than the extant geographical populations The observations are not fully compatible with speciation by strict allopatry At some species pairs parapatric speciation seems more reasonable in speciation of Arabidopsis The 98 gene sequences are also used for the congruence test between gene genealogy and species phylogeny Only 28 genes support the species phylogeny but there are 23 genes supports another major genealogy { lyrata} thaliana Based on the phylogenetic position change of A lyrata ssp kamchatica and Ks value for each species pair suggested the recent directional gene flow between A halleri ssp gemmifera and A lyrata ssp kamchatica

阿拉伯芥是第一个完成基因体定序的开花植物，其基因体资讯提供植物学研究的重要依据；在解析阿拉伯芥属物种的亲缘关系以及种化机制等重要的演化议题时，阿拉伯芥近缘的野生物种自然成了不可或缺的关键；跟阿拉伯芥近缘的物种包括A halleri及A lyrata，其中A halleri ssp gemmifera主要分布於中国东北、日本以及台湾，与近缘的A halleri ssp halleri其分布於欧洲隔著天山及大陆的障蔽，而A lyrata ssp kamchatica主要分布於东北亚及台湾，与分布於北美五大湖的A lyrata ssp lyrata被北极圈所分隔，这样的分布模式暗示异域种化的可能。藉由多基因分析比较祖先物种与现生物种遗传歧异度的相关可提供讯息探讨种化时期的族群遗传结构，本研究针对A halleri ssp gemmifera、A halleri ssp halleri及A lyrata ssp kamchatica、A lyrata ssp lyrata四个物种，两对互为亚种的姊妹群，以阿拉伯芥为外群进行研究，在四个物种完成98个同源基因的分子序列，利用套装软体MCMCcoal来估算祖先物种的遗传变异，亦估算现生物种的核苷酸歧异度，观察到？多物种配对中祖先物种遗传多型性大於现生物种DNA歧异度，显示异域种化模型并无法完全解释阿拉伯芥属物种的种化模式，在某些物种配对间邻域种化模式应比异域种化更为可能；在基因树与物种树的比较，98个基因片段的亲缘模式只有28个是与已知物种树一致的，有23个基因其树状图支持{ lyrata} thaliana的型式，藉由kamchatica位置的变化以及估算各物种配对间的平均同义置换率，推测在A halleri ssp gemmifera与A lyrata ssp kamchatica间具有近代的单方向基因交流。

Functional genomics, with emphasis on effects of auxin and brassinosteroid on development of plant

主要进行植物激素作用机理和植物种子发育功能基因组学研究。

The common key questions of industrial biotechnology are summarized as follows:(1)the pool of microbial resource and functional genomics of microbe;(2)effective methods for improving biocatalyst performance under industrial conditions;(3)metabolic engineering of important industrial microbes.

介绍了工业生物技术的关键问题是：（1）微生物资源库和微生物功能基因组学技术；（2）生物催化剂快速定向改造新技术；（3）重要工业微生物的代谢工程。

With the development of proteomic and genomics, the technology of molecular bionics has become the topic of biologic study in world.

随着基因组学和蛋白组学的研究进展，模拟活性蛋白合成仿生分子的研究越来越引起人们的关注。

The structure and organization of mitochondrial genomes of 14 marine bivalves and two freshwater bivalves were analyzed using comparative genomics and bioinformatics methods.

利用比较基因组学和生物信息学方法，比较分析了已登录到GenBank中的14种海产双壳贝类和2种淡水双壳贝类的线粒体基因组的结构特征。

The book focus on the development of molecular diagnostic tools and genetic evolution and its relationship to pathogenicity, and includes other topics such as Brucella comparative genomics and proteomics, analysis of the structure, biosynthesis and biology of glucans and lipopolysaccharides, pathogenicity, approaches to vaccine development, bacterium-host interactions, immune response, and much more.

该书聚焦于分子诊断工具的发展和遗传进化及其与病原性的关系，并且包括其他的主题，例如布鲁氏菌的比较基因组学和蛋白质组学，结构分析，葡聚糖和脂多糖的生物合成和生物学，病原性，疫苗生产的方法，细菌与宿主的关系，免疫反应，以及更多的内容。

The contraction of genetic map using marker information and mapping QTL are the core of Statistical Genomics.

利用群体的遗传标记信息构建动植物的遗传图谱和定位分析影响数量性状的基因位点是统计基因组学的核心内容。

The expressed protein concentrates were about 0.5-5mg/L. 3. Classification and functional annotation of kinases have been studied: according to the kinases Classification in PlantsP (http://plantsp.genomics.purdue.edu/), 27 kinases belong to 7 groups in the class 1 of Transmembrane Receptor Kinase and Related non-Transmembrane Kinases on PlantsP, namely Receptor like cytoplasmic kinaseⅦof group 1.2, CRPK1 Like Kinase of group 1.3, Crinkly 4_Like kinase of group 1.4, Plant Extemal Response Like Kinase of group 1.6, CRPK1 Like Kinase (Types 1 and ) and S-Domain Kinase (Type 2) of group 1.9, Legume Lectin Domain Kinase of group 1.11, Wall associate kinase of group 1.5, respectively. 4. 21 kinases expressed in S.

对获得的蛋白激酶进行了分类和功能预测：按照PlantsP网站(http：//plantsp.genomics.purdue.edu/)的激酶分类系统，本实验表达的激酶分别属于第一类跨膜受体激酶和无跨膜区的激酶中的7个不同组，即第2组的Receptor LikeCytoplasmic KinaseⅦ家族、第3组的CRPK1L(Type 1)家族、第4组的Crinkly 4_Likekinase家族、第6组的Plant External Response Like Kinase家族、第9组的CRPK1 LikeKinase(Types 1 and 2)和S-Domain Kinase(Type 2)家族、第11组的Legume LectinDomain Kinase家族和第17组的Wall Associated Kinase kinase家族； 4。

Much research related to this model species has been done, such as cytogenetics, genomics and genetic transformation.

在短短几年中人们对这一模式植物在细胞遗传学、基因组学以及遗传转化等方面进行了大量研究。

It's not quite as simple as that.

并没有那么容易。

It debuted in 1992 in Japan and the United Kingdom, and 1993 in the United States.

它首次亮相于1992年在日本和英国，在美国1993年。