查询词典 epi-

The growth inhibiting rate of T24 cell lines were detected by MTT methods, apoptosis of cells were detected by flow cytometry, the mechanism of apoptosis was analyzed by detecting the protein expression of Bcl-2, Bax, Caspase-9, Caspase-3 and cytoplastic protein Cytochrome C. 4 We injected live T24 cells into the subcutaneous space of nude mice and successfully built up the animal model of bladder carcinoma. The effect of CS-PAA-EPI polymer magnetic microspheres targeting chemotherapy was investigated by HE staining, TUNEL ,tumor weight and volume inhibition rate. Results: 1 TEM revealed that the CS-PAA polymer magnetic microspheres were regular spherical shape,the average diameter was 80nm in dry condition. By controlling the pH value of the medium,polymers had positive or negative zeta potential. VSM showed the CS-PAA polymer magnetic microspheres had superparamagnetic. The diameter of CS-PAA-EPI polymer magnetic microspheres were 200nm in solution by DLS examining,the embedding ratio was 20%,the EPI loading rate was 15%, which was higer than reported in other articles. 2 Raw eye observation found that the rat"s bladder of treatment group was brown color,which meaned the aggregation of iron particles, compared with the control group, iron stain found iron particles were assembled in rat"s bladder of the treatment group, the amount of iron particles in liver and spleen were less obviously.

研究结果：1合成的CS-PAA磁性聚合物微球呈球形，大小均一，TEM测定其干态下粒径为80nm左右，磁化曲线证实具有超顺磁性，具有一定的PH敏感性，固载表柔比星后，水溶液性状稳定，无沉淀物，DLS测定直径约200nm左右，测定载药率为15％，较文献报道高，包封率为20％。2肉眼观察试验组大鼠膀胱表面呈褐色，可见大量的Fe粒子聚集，普鲁士兰染色法显示，试验组大鼠膀胱壁内有大量的Fe粒子，分布至膀胱壁全层，与对照组大鼠相比，试验组大鼠的肝、脾内的Fe粒子聚集量明显降低；HPLC测定结果与Fe染色相同；高剂量磁性CS-PAA-EPI生理盐水组及单纯EPI生理盐水组均在给药后14天出现血肌酐和尿素氮的升高，其他组大鼠血生化指标没有明显变化。3MTT法发现，高、中、低剂量磁性CS-PAA-EPI生理盐水组在外加磁场的协同作用下杀伤T24细胞效应明显高于单纯的EPI生理盐水组，FCM发现试验药物组可引起明显的肿瘤细胞凋亡，试验药物治疗组细胞胞浆内出现了由线粒体释放出的细胞色素C，试验组细胞Bcl-2蛋白减少，Bax蛋白变化不明显，Caspase-3、Caspase-9蛋白受到了激活活化。4高、中、低剂量磁性CS-PAA-EPI生理盐水组的瘤重抑制率和瘤体积抑制率均明显高于单纯的EPI生理盐水组(P＜0.01)，其中高剂量组的抑制率最高。

The complexity of this idea is reflected in the variety of constructions used with the verb (a hoti clause, or accusative and infinitive, expressing truth believed; en and epi with the dative, denoting restful reliance on that to which, or him to whom, credit is given; eis and, occasionally, epi with the accusative, the most common, characteristic, and original NT usage, scarcely present in the LXX and not at all in classical Greek, conveying the thought of a move - ment of trust going out to, and laying hold of, the object of its confidence).

的复杂性，这一主张是反映在各种建筑用的动词（一霍蒂条款，或accusative和不定式，表示相信真理； EN和计划免疫与格组成，代表宁静的依赖，为这，还是他的人，信用是鉴于； EIS的，偶然计划免疫与accusative ，最常见的，特点，以及原新台币使用，目前几乎在lxx并没有这回事，在古典希腊语，传达思想的举动-m ent信托走出去，并铺设举行的，该物体的，其可信度）。

Containing many T cell epi-positions and neutralizing antibody epi-positions, the core protein region and envelope protein 2 of Hepatitis C virus structural protein may induce protective immunity responsion in body.

丙型肝炎病毒(hepatitis C virus，HCV)结构蛋白的核心蛋白和包膜蛋白2(E2)含有多个T细胞表位和中和抗体表位，可诱导机体产生保护性免疫应答。

ASES is 59% identical to Artemisia cyclase cDNA clone cASC125, 50% identical to epi-cedrol synthase from A. annua, 48% identical to amorpha-4, 11-diene synthase from A. Annua, 39% identical to the 5-epi-aristolechene synthase from tabacco, 38% identical to vetispiradiene synthase from H. Muticus, 41% identical to the δ-cadinene synthase from cotton. The coding region of cDNA was cloned into procaryotic expression vector pET30a and overexpressed in E. coli BL21 (DE3). The cyclase proteins extracted from bacterial culture were found largely in the insoluble protein fraction. The tissue specific expression patterns were analyzed by RT/PCR.

克隆的倍半萜合酶氨基酸序列与烟草马兜铃烯合酶、莨菪岩兰螺旋二烯合酶、棉花杜松烯合酶的一致性分别为39％，38％和41％；与青蒿柏木脑合酶、紫穗槐二烯合酶和一个推测的倍半萜合酶克隆cASC125的一致性为50％，48％和59％。cDNA编码区序列被克隆进原核表达载体pET-30a，并在大肠杆菌BL21（DE3）中诱导表达，但过量表达的蛋白主要是以不溶性蛋白形式存在。

At last,a convergent and general protocol to marine natural product,as demonstrated by the enantioselective total synthesis of malyngamides O,P,Q,R, 5"-epi-Q and 5"-epi-R bearing terminal vinylic chloride structure,was developed in detail.E,(7S)-7-methoxytetradec-4-enoic acid was prepared using the above described Johnson-Clainsen rearrangement,the terminal vinyl chloride was constructed using Wittig reaction as key step,the pyrrolidone derivative was constructed using L-serine as natural chiral pool.Starting from the synthesis of malyngamides O and P to explore the general route,an aldol reaction of methyl acetate with the vinyl chloride part in the presence of LDA gave the skeleton of amine portion,followed by amidation with the fatty acid finished the synthesis of malyngamide P.

先以malyngamides O和P为试点探索通用合成路线，将乙酸甲酯和烯氯部分在LDA存在下进行aldol反应得到氨部分的骨架，再将手性不饱和脂肪酸和氨部分进行酰胺化反应完成了malyngamide P的合成，将P在碱性条件下进行烯醇甲基化反应完成了malyngamide O的全合成。

The complexity of this idea is reflected in the variety of constructions used with the verb (a hoti clause, or accusative and infinitive, expressing truth believed; en and epi with the dative, denoting restful reliance on that to which, or him to whom, credit is given; eis and, occasionally, epi with the accusative, the most common, characteristic, and original NT usage, scarcely present in the LXX and not at all in classical Greek, conveying the thought of a move - ment of trust going out to, and laying hold of, the object of its confidence).

的复杂性，这一主张是反映在各种建筑用的动词（一霍蒂条款，或accusative和不定式，表示相信真理； EN和计划免疫与格组成，代表宁静的依赖，为这，还是他的人，信用是鉴於； EIS的，偶然计划免疫与accusative ，最常见的，特点，以及原新台币使用，目前几乎在lxx并没有这回事，在古典希腊语，传达思想的举动-m ent信托走出去，并铺设举行的，该物体的，其可信度）。

Materials and Methods:236 pathology-confirmed breast lesions(155 malignanty,81 benignancy) and 221 disease-free contralateral breast tissues were examined using EPI-DWIb values=0,1000 s/mm~2TR/TE=8400ms/93.8ms; FOV=30×30cm;matrix=128×128;ASSET=2,slice thickness=4mm.DCE-MR imaging was also performed for accurate location of the lesion using VIBRANT sequence.The mean ADC values of malignant and benign lesions and the disease-flee contralateral breast tissues were calculated from the ADC map for each patient.One-way analysis of variance was applied to compare the mean ADCs of malignant lesions with benign lesions and disease-flee contralateral breast tissues.The threshold ADC value for malignant lesion was determined using a receiver operating characteristic(ROC curve analysis.Each lesion was classified into two major types:mass and non-mass lesion.The diagnostic performance of DWI was compared in breast mass and non-mass lesions.Results:155 malignant and 81 benign lesions were confirmed in 236 lesions.

材料与方法：搜集术前行乳腺MR检查并经穿刺或手术病理证实的236例乳腺病变，以对侧正常乳腺腺体作为正常对照，采用横轴位的平面回波-扩散加权成像序列，TR=8400ms，TE=93.8ms，层厚=4mm，激励次数=2：视野=30×30cm，矩阵=128×128，ASSET=2，b值=0和1000s/mm~2；参考动态增强图像准确定位，测量病变区和对侧正常乳腺腺体的ADC值，应用t检验比较良、恶性病变及正常腺体ADC值的差异，采用接收者工作特征曲线(receiver operating characteristic curve，ROC)确定良恶性病变的ADC界值；根据BI-RADS MRI将乳腺病变按照形态学表现分为肿块性病变和非肿块性病变两组，比较ADC值在肿块和非肿块性病变中定性诊断的效能。

They have investments in thisLouis Vuitton Epi Leather Porte Billets Billfold or that or the otherChanel Medium Tote here there and everywhere.

他们向这方面投资，又向那方面投资；在这里投资，在那里投资，到处都投资。

In this thesis, with special concerns focused on the effects on the EPI by field in the non-equilibrium transport through a single-molecular quantum dot, non-equilibrium Green function technique and canonical transformation method under the adiabatic approximation for the local electron-phonon system have been applied.

在对哈密顿量进行有效等价的基础上，采用非平衡格林函数方法处理外加偏压所导致的非平衡输运，系统地研究了耦合在两电极间的量子点。

Results］ After implementing EPI, 24270 cases in Polio, measles, diphtheria, whooping cough, encephalitis B and epidemic cerebrospinal meningitis, as well as 365 cases dead and 70 cases handicapped were reduced annually.

结果］ 实施计划免疫后，年均减少脊髓灰质炎、麻疹、白喉、百日咳、乙脑和流脑等6种传染病共24 270例，减少死亡365例，减少残疾70例。

His female bullfighter Lydia gradually Health love, but she was in a vegetative state after the Bulls Zhuangcheng away from her, just because Lydia's ex-boyfriend showed more affectionate than he is like love.

他对女斗牛士莉迪亚渐生爱意，却在她被公牛撞成植物人后离她而去，仅仅因为莉迪亚的前男友表现出好似比他更深情的爱。

I know of none which are not easy to answer, but what I am trying to do now is only by a series of hints to throw some light on the narrow path of legal doctrine, and upon two pitfalls which, as it seems to me, lie perilously near to it.

我不认为有什么难以回答的问题，但我现在要做的仅仅是通过一系列线索，来给法律理论的狭窄路径以及在我看来离它近得危险的两个陷阱提供一些启示。