查询词典 differentiation
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Though can not accurate induce neural stem cells specific orientation differentiation yet,to accompany the unceasing deepen recognize of convection mechanisms in cells' signal convection and discovery of new cell facter,new chemo-signal, Homo sapiens would solve the question of orientation differentiation from totipotential stem cell,multipotential stem cell to neural stem cell, orientation nerver ancestor cell then special tipe neural cell, implementation functional reconstruction betwen neural cell,for ultimate solve the proble of neural regeneration developing the way.
尽管目前尚不能准确有效的诱导神经干细胞特异性定向分化为某种特定的神经元,但随着人们对细胞间信号传递机制认识的不断加深和新的细胞因子、化学信号的不断发现,人类将能够解决从全能干细胞、多能干细胞到神经干细胞、定向神经祖细胞直至特异类型神经细胞的定向分化,完成神经元之间的功能重建,为最终解决中枢神经再生这一难题而开辟道路。
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The original alkalic series of basalic magma evolutes into trachybasalt through crystallization differentiation of olivine and pyroxene, and the trachybasalt is transformed into alkalic rhyolite with remarkable Eu, Sr, Ba, Ti, P nagetive abnormalities through strong crystallization differentiation of plagioclase and also pyroxene Ti Fe oxides and apatite, all together leading to the loss of neutral (SiO 2=57%~63%) andesite and trachyandesite in the volcanic rocks in this area and appearance of bimodal volcanic rock combination feature.
原始碱性系列玄武质岩浆经橄榄石、辉石的结晶分异,向粗面玄武岩演化;粗面玄武岩经斜长石强烈的结晶分离作用,还有辉石、钛铁氧化物和磷灰石的分离结晶作用形成具显著Eu、Sr、Ba、Ti、P负异常的碱性流纹岩,导致本区火山岩缺失中性(SiO2=57%~63%)的安山岩和粗安岩,呈现双峰式火山岩组合的特点。
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There is a positive relationship between the expression of hMSH2 mRNA and the grade of gastric cancer differentiation. hMSH2 may induce the cell differentiation and regulate the gastric cancer cells in transcriptive level.
hMSH2 mRNA表达与胃癌分化程度有关,胃癌细胞的分化程度愈低,其hMSH2 mRNA表达愈低。hMSH2可能对胃癌细胞存在分化诱导或转录水平调控。
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In this thesis, we find that dlg is indispensible in the establishment of anterior-posterior and dorsal-ventral polarity of drosophila oocyte. Removal of Dlg function from the posterior follicle cells using the FLP/FRT system leads to disruption of oocyte skeleton reconstruction that is elicited by the failure of those posterior cells to differentiate normally in mid-oogenesis. We demonstrate that abnormity of Notch, JAK-STAT and EGFR signal pathway in dlg mutants contributes to this aberrant differentiation. dlg null mutant also blocks the normal differentiation of two groups of anterior follicle cell-stretched cell and centripetal cell, but not border cell, with a lower penetrance. However unlike the result in posterior follicle cells, Notch and JAK-STAT signaling are both undisrupted in all mutant anterior follicle cells, implying other fate determinants may be involved.
我们的研究发现,后端滤泡细胞中的Dlg在果蝇卵子发生中期卵母细胞前后轴和背腹轴建立过程中也是必须的,PFC中dlg完全缺失型突变引起PFC的分化异常,导致卵子发生中期卵母细胞骨架重组异常,Stau、Grk等极性决定蛋白定位错误。dlg突变阻碍了Notch、JAK-STAT、EGFR等调节PFC分化的信号通路的激活。dlg突变的PFC也没有获得前端滤泡细胞命运。dlg突变不影响前端滤泡细胞群中边界细胞的分化,但是在一定程度上影响伸展细胞和向心细胞的分化,并且这种影响不依赖于前端滤泡细胞Notch或JAK-STAT信号激活的异常。
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In this study, We used longer DD primers in combination with a two-step PCR protocol to overcome these two problems in term of modified methods of Martin and Pardee.K562 erythroleukemia cell differentiation induced by HEMIN or PMA for 36 hours was used as erythriod or megakaryocytic differentiation model in vitro.Total RNAs were extracted from induced and uninduced K562 cells and were applied to mRNA differential display analysis.
为解决此问题,我们参照Martin和Pardee的改进方案[3],建立了一种使用长引物,进行二步PCR的改进DDRT-PCR方法,以氯高铁血红素和肉豆蔻佛波酯诱导K562细胞36小时作为体外红细胞和巨核细胞分化模型,取诱导前后的细胞总RNA进行mRNA差异显示分析。
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The effects of vacuolization on the differentiation of vascular endothelial cells were analyzed from a chemical biochemistry genetics perspective using the blastodisc cells differentiation model induced by FGF with the γ-butyrolactones derivative.
从化学遗传学的角度,利用γ-丁内酯衍生物研究了成纤维细胞生长因子(fibroblast growth factor, FGF)诱导鸡胚盘细胞向血管内皮细胞分化过程中,空泡化对血管内皮细胞分化的影响。
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Lithologies are mostly sand and carbonate rocks, caps are mud rock, shale and magmatite. Entrap types are anticline, fault block rebuilt by breaking and the screened entrap diapered rock mass. The composition is CO_2, N_2, CH_4, C_2H_6 and He etc. It is magma air source body and its geologic fashions are intrusion and buried volcanic conduit. The relations between gas reservoirs and gas source bodies have three types: magma intrusion-breaking-communicated gas reservoir, magma intrusion-contacted CO_2 reservoir and buried volcanic conduit-contacted gas reservoir. The CO_2 migration in magma intrusion is consisted of fusing and crystallizing phases;it in volcanic conduit is consisted of near-surface effusion and crystallizing phases.The buoyancy of CO_2 in water far more than migration resistance in breaking or chink, CO_2 is easy float upward, the floating can results in differentiation of different density gases and concentration of sealed gas. The gas in sand reservoir firstly migrate into the higher porosity and coefficient of permeability sand, and along with the pressure going up it migrate into the lower. In magma intrusion-breaking-reservoir migration, CO_2 firstly migrate into watered breaking, began gravity differentiation and concentrate, the gas pressure time and again go up, CO_2 migrate into reservoir and concentrate under expansibility as the pressure reach upward a given extend. The CO_2 in reservoir experience four breaking modes: chemistry deposition, dissolution, diffusion and mechanic breaking, the pressure balance can be broken by faulting and the CO_2 will further migrate and form new reservoir.
济阳坳陷已发现的八里泊、阳25、平方王、平南、高青、花17 CO_2气藏主要储集层位有奥陶系、中生界、沙四段、沙三段、沙一段、馆陶组和明化镇组,储集层岩性以砂岩和碳酸盐岩为主,盖层以泥质岩、页岩和岩浆岩为主。;圈闭类型主要为受断裂改造的背斜、断块及刺穿岩体遮挡圈闭。;气体成分主要有CO_2、N_2、CH_4、C_2H_6、He等。;主要气源体为岩浆气源体,气源体的主要地质形式为侵入体和埋藏的火山通道。;气藏和气源体的空间关系有岩浆侵入体一断裂一气藏沟通型、岩浆侵入体-CO_2气储集层接触型和埋藏火山通道-气储集层接触型三种类型。;岩浆侵入体CO_2气运移分为熔融运移阶段和结晶运移阶段,火山通道中CO_2气运移分成近地表喷发阶段和结晶运移阶段。;断裂中,CO_2在水中的浮力远大于运移阻力,CO_2气容易上浮,CO_2在断裂中的易浮性导致不同密度气体的分异和走向上封闭的断裂气体相对富集。;气体在砂岩储集层运移聚集具有选择性,会优先进入孔隙度和渗透率较高的砂岩,随着压力增加,才会进入孔隙度和渗透率较低的砂岩;在岩浆气源体-断裂-储集层空间输导格架下,CO_2气在膨胀力的驱动下,首先进入含水的断裂并重力分异而聚集,气体压力会不断增高,当压力增至一定程度,CO_2气会向高孔隙度、渗透率的储集层运移并聚集。;在岩浆气源体-储集层接触空间输导格架下,CO_2气受膨胀力的驱动直接向储集层运移并聚集。;成藏的CO_2气会经历化学沉淀、溶解、扩散和机械破坏四种破坏方式,会受断裂切割而打破压力平衡,沿断裂进一步运移和聚集成藏。
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The results showed as following: NMB was suitable for the callus induction, and MS for differentiation.500 mg/L of Glu or Arg redounded to the callus induction.All the cultures were kept under dark, 25-28 ℃, pH 5.8 for callus induction; and 25-28 ℃, 1 500-2 000 lx,12-14 h/d,pH 5.8 for differentiation.6-BA shows a significant result on the growth of callus;The optimal concentration of hygromycin is 50 mg/L.
结果表明:NMB培养基适合水稻成熟胚盾片愈伤组织诱导,MS培养基适合愈伤分化;500 mg/L谷氨酰胺或精氨酸有利于愈伤组织的形成;培养条件:愈伤组织诱导时温度25~28 ℃,暗培养,pH 5.8;分化时温度25~28 ℃,光照1 500~2 000 lx,12~14 h/d,pH 5.8;6-BA对继代过程中愈伤组织的生长有促进作用;潮霉素筛选的最佳浓度为50 mg/L。
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On one hand, farmland is a kind of security for farmers in the primary stage of professional differentiation. On the other hand, it makes farmers reluctant to completely leave their farmland, which universalizes the diversity of farmers'professions and hinders further development of professional differentiation.
一方面,土地是职业分化初级阶段农民的保障手段;另一方面,它又使得农民不愿彻底脱离农业和农村,导致农民的兼业化,进而阻碍农民进一步的职业分化。
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Only 10-day pretreatment of germinated seeds at 5℃ or 10℃ was enough to enhance the floral bud differentiation in the spring variety 'Duanye 13', whereas at least 20-day pretreatment was required for the promotion of floral bud differentiation in the winter variety 'Yidianhong'.
0.10一1.00mmol/l的5一azaC处理萝卜种子3一6d可以促进花芽分化和开花,这种促进效果在春性品种'短叶13'中更加明显。
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This paper designs the communication system of radio telescope FAST.
针对500m口径球面射电望远镜FAST分布式控制系统的特点完成了其通信系统的设计。
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Political sheep's step-by-step a large number of fossils unearthed in the county soil Ma Ali after rural village in the middle of sallow pelitic siltstone.
步氏和政羊化石大量出土于广河县阿力麻土乡后山村,产于灰黄色泥质粉砂岩中。
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If you start very rapidly with high dose you will have flatulence just as if you were to take a high fiber diet but if you start very slowly and low dose and titrate very slowly then you will avoid most of the dose symptoms.
如果您以高剂量快速开始,您会有如同摄入高纤维饮食似的肠胃气胀;但是,如果您以低剂量缓慢开始,并且缓慢滴定,您将可避免绝大多数剂量依赖性症状。