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The 20S catalytic core of the 26S proteasome has the shape of a barrel made of four rings which are composed of seven differentαsubunitsα_1-α_7 at two outer rings and seven differentβsubunitsβ_1-β_7 at two inner rings at which the catalytic sites locate. Three of theβsubunits contain proteolyses sites, which are sequestered in the hollow interior of the 20S particle. Substrates enter the 20S through a narrow channel formed by theβsubunits, whose N-termini, depending on their conformation, can either obstruct or allow substrate entry and thus function as a gate. This entry channel is narrow and only permits passage of unfolded, linearized polypeptides.

哺乳动物26S蛋白酶体是由一个20S催化颗粒(catalytic particle，CP)和两个19S调节颗粒(regulatory particle，RP)组成的ATP(adenosine-triphosphate，ATP)依赖性蛋白水解酶复合体。20S CP是26S蛋白酶体的催化核心，它是由4个圆环堆叠形成的桶状复合物，其中两侧外环每个环是由α_1-α_7亚基组成，两个内环每个环是由β_1-β_7亚基组成，4个环的中央形成一个狭窄的内腔。2个β内环形成了20S CP的催化中心空腔，其内壁为催化活性位点所在地；外侧α环中心的孔道是底物到达催化中心空腔的通道，一般被α亚基上的N末端所封闭，阻止胞内非目的靶蛋白进入20S CP内被降解破坏。

The beautiful young singer describes herself as a country girl and as such, is more interested in rural styles like the funana, bataku and the European, colonial-based mazurka than in the more urban morna, a barroom blues associated with the elder diva. Her songs, many of them self-composed, deal with small-town realities like a mother's advice to her son in hard times, an unplanned pregnancy, uninhibited holiday celebrations and other tales that might well be discussed on a neighbor's door-step.

出生葡萄牙里斯本、既是歌手也是舞者的露拉，虽不是土生土长的维德角人，但自幼於里斯本领受欧洲与南美文化交界、多元文化混杂的影响，再加上父亲偏好融合葡萄牙Fado、拉丁曲调和非洲节奏的维德角传统民谣Morna、Coladera等，使得露拉的音乐不但有南美热情奔放的特性，也兼容了维德角抒情民谣Morna甜美感伤的情绪。

The Pisan Bartolommeo of San Concordio has left us a "Summa Casuum" composed in 1338, in which the matter is arranged in alphabetical order.

该pisan bartolommeo圣孔科尔迪奥给我们留下了一个"总结casuum "组成，在1338年，在这件事是安排在字母顺序排列。

Girolamo de Fornariis subjected to examination the polemic of Pomponazzi with Augustin Nifi (Bologna, 1519); Bartolommeo de Spina attacked Cajetan on one article, and Pomponazzi in two others (Venice, 1519); Isidore of Isolanis also wrote on the immortality of the soul (Milan, 1520); Lucas Bettini took up the same theme, and Pico della Mirandola published his treatise (Bologna, 1523); finally Chrysostom Javelli himself, in 1523, composed a treatise on immortality in which he refuted the point of view of Cajetan and of Pomponazzi Chrysostomi Javelli,"Opera", Venice, 1577, I-III, p.

吉罗拉莫德fornariis受到考试论战的蓬波纳齐与奥古斯丁nifi （博洛尼亚， 1519 ）； bartolommeo德脊柱攻击cajetan对一的文章，和蓬波纳齐在另外两个（威尼斯， 1519 ）；伊西多尔的isolanis也写就了不朽的灵魂（米兰， 1520 ）；卢卡斯bettini了同样的主题，和微微的梅兰多拉发表论文（博洛尼亚， 1523 ）；终於金口javelli自己，在1523年，组成一伤寒论神仙在他反驳的角度来看， cajetan和蓬波纳齐（ chrysostomi javelli ，"戏曲"，威尼斯， 1577年，我第三次，第52页）。

All the volcanic rocks present younger K-Ar age (less than 5Ma), which can be termed as Cenozoic rocks. In general speaking, volcansim can be dividied into two eruptive stages. In the first stage, volcanic rocks for Pliocene epoch (4. 4-5Ma) consist of basanite and tephrite, which distributed on Mt. Crater, Cape Bird, and southern bank of Bonney Lake; In the second stage, volcanic rocks for Quaternary (less than 1 Ma) are mainly composed of latite, which are distributed on Cape Rodeys and Cape Evens.On the basis of geochemical data such as major elements, trace elements , rare earth elements, isotope, microprobe analysis, combined with main achievement taken by previous researcher in this area, conclusions are drawn basically as follows

所喷发的火山岩K-Ar年龄值均小于5Ma，为新生代火山岩，大体上可以分为两个喷发阶段，第一个阶段为上新世火山岩(年龄值为4.4-5.0Ma)，主要由碧玄岩和碱玄岩组成，分布于罗斯岛上的克雷克特山、鸟角和泰勒谷的博尼湖南岸；第二阶段为第四纪火山岩(年龄值均小于1Ma)，主要由安粗岩组成，分布于罗斯岛上的罗德角和伊万思角，通过主要元素、微量元素、同位素结合电子探针以及前人的研究成果，我们大体上可以得出如下认识

Most of salesman's salary is composed by base pay and one percent deduct.

大多数销售人员的工作报酬是基本工资外加一个百分比提成。

"In literature, Basho developed poetic forms later called haiku, and Ihara Saikaku composed virtuoso comic linked-verse and humorous novel s."

在文学方面，江户时代见证了松尾芭蕉手中俳句的发展，还有匠心独具的喜剧式连环诗作及井原西鹤的幽默小说。

"In literature, Basho developed poetic forms later called haiku, and Ihara Saikaku composed virtuoso comic linked-verse and humorous novels."

在文学方面，江户时代见证了松尾芭蕉手中俳句的发展，还有匠心独具的喜剧式连环诗作及井原西鹤的幽默小说。

Most of the rest of the poem is composed of Basil's account of his deeds, given to his friends over dinner.

其它的诗歌大多数都是描述瓦西里的事迹，以及为他的朋友们举行的盛宴。

Basing on this thought, this paper is composed of four chapters.

根据这个思路，本文共分为四个部分。

This paper designs the communication system of radio telescope FAST.

针对500m口径球面射电望远镜FAST分布式控制系统的特点完成了其通信系统的设计。

Political sheep's step-by-step a large number of fossils unearthed in the county soil Ma Ali after rural village in the middle of sallow pelitic siltstone.

步氏和政羊化石大量出土于广河县阿力麻土乡后山村，产于灰黄色泥质粉砂岩中。