查询词典 chaperone

The effect of guanidine hydrochloride concentration on the oxidative refolding of denatured-reduced lysozyme of high concentration in the presence of artificial chaperone , that is, cetyl trimethyl ammonium bromide and β-cyclodextrin,was studied.

研究了表面活性剂十六烷基三甲基溴化铵加β-环糊精和盐酸胍对高浓度变性-还原溶菌酶氧化复性的影响，利用基于二态复性模型的表观动力学模型分析了溶菌酶的复性过程。

The transparency is mainly related to the role of molecular chaperone in α-crystallin.

晶状体透明性与具有分子伴侣活性的α-晶体蛋白密切相关。

ObjectiveTo evaluate the effect of glycation on α-crystallin molecular chaperone activity.

目的 研究糖基化对α-晶状体蛋白分子伴侣活性的作用。

Signal peptide sequence was removed lest it couldnt be recognized by Bacillus subtilis, gene coding for mature peptide was ligated to downstream of sacB signal peptide sequence of pWB980 to form a new ORF and generate pWB980-LipA, gene coding for its chaperone was also amplified and ligated to the downstream of LipA to generate a secretion/expression vector pWB980-LipAB.thechaperone gene was sequenced and analyzed by multiple alignments, resulted showed that there were mutations of nucleotides(1～7) and amino acids (1～2) with the other reported genes.

为了防止枯草芽孢杆菌信号肽酶不能识别脂肪酶的信号肽，切除掉脂肪酶的信号肽编码序列，与枯草芽孢杆菌分泌表达质粒pWB980连接并与质粒上的SacB信号肽构成一个完整的开放式阅读框，获得重组质粒pWB980-LipA，因为该脂肪酶的活性表达需要一个特异性分子伴侣帮助折叠成有活性的构象，将脂肪酶分子伴侣基因串连到脂肪酶基因的下游，获得重组分泌表达载体pWB980-LipAB并且测序分析分子伴侣的基因序列和氨基酸序列并与其它报导的序列进行了比对，发现有1到7个碱基的差异和1到2个氨基酸残基的突变。

Molecular chaperone ORF1-ORF2 could enhance Cry11Aa expression amount to a certain extent with an unknown mechanism, but did not have an effect on high mosquitocidal toxicity of Cry11Aa protein.

推测晶体蛋白Cry11A能否成功表达与其使用启动子的类型和两者的协调配合有关。

Nevertheless, no homologues of typical molecular chaperones have so far been found in periplasm, and the recently reported chaperone activities of periplasmic protein disulfide isomerase and peptidyl pro-lyl isomerase seem to be too weak to satisfy such assumed needs.

虽然膜间质中的蛋白二硫键异构酶和脯氨酸顺反异构酶最近被报导具有分子伴侣活性，但是这种活性的检测使用的不是天然的膜间质蛋白，而且没有捕获到复合物的形成，因此看起来仍不能够满足前面分析的对膜间质蛋白保护的需求。

The study suggests that Sso7d has the chaperone ability and fusion with Sso7d is a practical way to engineer thermostable protein.

本研究暗示了Sso7d可能具有chaperone的功能，并且利用Sso7d融合蛋白去设计制造具耐热性的蛋白质是种可行的方法。

The team first determined that, in the presence of HDAC inhibitors, Hsp90 is acetylated and chaperone activity is inhibited.

该研究小组首先明确了，当HDAC抑制剂存在时，Hsp90是以乙酰化形式存在并且其伴侣活性被抑制。

The C-terminal tail of SecA occludes the groove and inhibits signal-peptide binding, but autoinhibition is relieved by the SecB chaperone.

SecA的C端尾巴封闭了沟，抑制信号肽的结合，但是自动泛素化作用被SecB伴侣分子阻止。

The chaperone activity of porcine kidney peptidyl-prolyl cis-trans isomerase was studied. The results showed that inactive or active PPIase was able to improve the refolding yields of creatine kinase , and inhibited aggregation. However, alkylated PPIase was not able to prevent CK aggregation.

研究猪肾脯氨酰顺反异构酶的伴侣功能时发现有活性和无活性PPIase能够提高肌酸激酶再折叠产量，抑制肌酸激酶聚沉，但是烷基化PPIase丧失防止肌酸激酶聚沉的能力。

Warden: That's a beautiful dog, but don't bring her again.

那是条漂亮的狗，但是不要再把她带来了。

You get up in the morning – no hangover!

你第二天早上起来的时候—不会宿醉！