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autacoids相关的网络例句

查询词典 autacoids

与 autacoids 相关的网络例句 [注:此内容来源于网络,仅供参考]

Cinnamomea, antrocamphin A was purified from previous ethanol extraction using bioactivity-guided fractionation. As results, the antrocamphin A could significantly inhibit NO and PGE2 autacoids production in LPS-induced RAW 264.7 macrophage cells. Meanwhile, the mRNA and protein expression levels of iNOS and COX-2 were inhibited by antrocamphin A in a dose-dependent manner. Antrocamphin A also reduced the translocation of NF-κB induced by LPS, which was associated with the prevention of the degradation of I-κB, and subsequently decreased p65/p50 proteins level in the nucleus. This is the first report demostrating the A.

接著并以活性为导向的分离策略,从樟芝子实体乙醇抽出物中分离出具抗发炎活性成分antrocamphin A,续利用LPS诱导小鼠巨噬细胞(RAW 264.7)产生发炎的模式,解析antrocamphin A之抗发炎机制,结果证实antrocamphin A确可有效抑制一氧化氮自由基和前列腺素的生成,透过蛋白质表现分析得知,antrocamphin A之抗发炎活性是经由抑制一氧化氮生成酵素和第二型环氧酵素的mRNA表现,进而抑制了一氧化氮生成酵素、第二型环氧酵素和核转录因子-κB等酵素之表现。

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