complement-binding
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Here we report that there is a dramatic decrease in the ability of a broadly neutralizing antibody to protect macaques against SHIV challenge when Fc receptor and complement-binding activities are engineered out of the antibody.
但一项新的研究表明,抗HIV抗体在以两种方式发挥作用时最有效:一种是通过中和,即直接杀死病毒,阻止其进入T-细胞;另一种是通过杀死感染的细胞。
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The immunoglobulin like anti AChR antibody without complement binding activity is successfully made from a pathogenic anti AChR antibody IgG 637 by site directed mutagenesis.Key words:receptor, cholinergic;myasthenia gravis;point mutation;complement-binding;antibodies
本研究利用定点突变技术,从完型抗乙酰胆碱受体抗体IgG 637制备了不能激活补体的突变型抗乙酰胆碱受体抗体IgG 637/K 322 A,为最终制备出可用于治疗重症肌无力的无补体激活功能的单价抗乙酰胆碱受体抗体提供依据。
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complement deviation:补体转向
补体,防御素 Complement ; Alexin ; Cytase ; End body | 补体转向 Complement deviation | 补体结合 Complement fixation ; Complement binding
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diminished radix complement:基数反码
05.07.05 对二的补码 twos complement | 基数反码 diminished radix complement | 05.07.07 对九的补码 nines complement, complement on nine
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twos complement:对二的补码
05.07.04 对十的补码 tens complement, complement on ten | 05.07.05 对二的补码 twos complement | 基数反码 diminished radix complement